The DOI matches its Crossref record.
Mapping of Functional Neural Pathways by Autoradiographic Survey of Local Metabolic Rate with [ 14 C]Deoxyglucose
Abstract
If sufficient time has elapsed following an intravenous pulse of [ 14 C]deoxyglucose, the carbon-14 contents of the tissues of the central nervous system represent mainly the accumulated phosphorylated derivative of [ 14 C]deoxyglucose and reflect the rates of glucose consumption of the tissues. Altered functional activity alters metabolic activity and the uptake of [ 14 C]deoxyglucose in the tissues. By autoradiographic survey of sections of the central nervous system it is then possible to map all the regions with altered functional and metabolic activities in response to experimentally induced changes in functional state.
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Cited by
Sokoloff, L., Reivich, M., Kennedy, C., Rosiers, M. H. D., Patlak, C. S., Pettigrew, K. D., Sakurada, O., & Shinohara, M. (1977) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1977.tb10649.x · Cited by 6,000
Self-citationRELATION BETWEEN PHYSIOLOGICAL FUNCTION AND ENERGY METABOLISM IN THE CENTRAL NERVOUS SYSTEM
Sokoloff, L. (1977) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1977.tb03919.x · Cited by 807
Self-citationChance, B., Schoener, B., Oshino, R., Itshak, F., & Nakase, Y. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)30079-0 · Cited by 676
CNS energy metabolism as related to function
Ames, A. (2000) · Brain Research Reviews · doi:10.1016/s0165-0173(00)00038-2 · Cited by 663
Sokoloff, L. (1981) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.1981.4 · Cited by 580
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Metadata
- Authors
- Kennedy, C., Des Rosiers, M. H., Jehle, J. W., Reivich, M., Sharpe, F., & Sokoloff, L.
- Venue
- Science
- Published
- 1975-03-07
- Volume
- 187
- Issue
- 4179
- Pages
- 850-853
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1994625228
- Cited by
- 436
- References
- 0
- FWCI
- 8.92
- Type
- journal article
- Language
- en
- Open access
- closed
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- Kennedy, C., Des Rosiers, M. H., Jehle, J. W., Reivich, M., Sharpe, F., & Sokoloff, L. (1975). Mapping of Functional Neural Pathways by Autoradiographic Survey of Local Metabolic Rate with [ 14 C]Deoxyglucose. Science. https://doi.org/10.1126/science.1114332
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
