The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
Containing Pandemic Influenza at the Source
Abstract
Highly pathogenic avian influenza A (subtype H5N1) is threatening to cause a human pandemic of potentially devastating proportions. We used a stochastic influenza simulation model for rural Southeast Asia to investigate the effectiveness of targeted antiviral prophylaxis, quarantine, and pre-vaccination in containing an emerging influenza strain at the source. If the basic reproductive number ( R 0 ) was below 1.60, our simulations showed that a prepared response with targeted antivirals would have a high probability of containing the disease. In that case, an antiviral agent stockpile on the order of 100,000 to 1 million courses for treatment and prophylaxis would be sufficient. If pre-vaccination occurred, then targeted antiviral prophylaxis could be effective for containing strains with an R 0 as high as 2.1. Combinations of targeted antiviral prophylaxis, pre-vaccination, and quarantine could contain strains with an R 0 as high as 2.4.
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Cites
Probable Person-to-Person Transmission of Avian Influenza A (H5N1)
Ungchusak, K., Auewarakul, P., Dowell, S. F., Kitphati, R., Auwanit, W., Puthavathana, P., Uiprasertkul, M., Boonnak, K., Pittayawonganon, C., Cox, N. J., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa044021 · Cited by 869
Self-citationTransmissibility of 1918 pandemic influenza
Mills, C. E., Robins, J. M., & Lipsitch, M. (2004) · Nature · doi:10.1038/nature03063 · Cited by 796
Containing Pandemic Influenza with Antiviral Agents
Longini, I. M. (2004) · American Journal of Epidemiology · doi:10.1093/aje/kwh092 · Cited by 705
Self-citationAre We Ready for Pandemic Influenza?
Webby, R. J., & Webster, R. G. (2003) · Science · doi:10.1126/science.1090350 · Cited by 655
A mathematical model for the global spread of influenza
A. Rvachev, L., & Longini, I. M. (1985) · Mathematical Biosciences · doi:10.1016/0025-5564(85)90064-1 · Cited by 524
Self-citationThe role of evolution in the emergence of infectious diseases
Antia, R., Regoes, R. R., Koella, J. C., & Bergstrom, C. T. (2003) · Nature · doi:10.1038/nature02104 · Cited by 515
Welliver, R. (2001) · JAMA · doi:10.1001/jama.285.6.748 · Cited by 463
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Inhaled Zanamivir for the Prevention of Influenza in Families
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Zanamivir in the Prevention of Influenza Among Healthy Adults: A Randomized Controlled Trial
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Cited by
Detecting influenza epidemics using search engine query data
Ginsberg, J., Mohebbi, M. H., Patel, R. S., Brammer, L., Smolinski, M. S., & Brilliant, L. (2009) · Nature · doi:10.1038/nature07634 · Cited by 4,295
Epidemic processes in complex networks
Pastor-Satorras, R., Castellano, C., Van Mieghem, P., & Vespignani, A. (2015) · Reviews of Modern Physics · doi:10.1103/revmodphys.87.925 · Cited by 3,697
Social Contacts and Mixing Patterns Relevant to the Spread of Infectious Diseases
Mossong, J., Hens, N., Jit, M., Beutels, P., Auranen, K., Mikolajczyk, R., Massari, M., Salmaso, S., Tomba, G. S., Wallinga, J., et al. (2008) · PLoS Medicine · doi:10.1371/journal.pmed.0050074 · Cited by 2,900
“Preparing for outbreaks of directly transmitted pathogens such as pandemic influenza [1] [2] [3] and SARS [4] [5] [6] [7] [8] [9] , and controlling endemic diseases such as tuberculosis and meningococcal diseases, are major public health priorities.”
BackgroundMultiscale mobility networks and the spatial spreading of infectious diseases
Balcan, D., Colizza, V., Gonçalves, B., Hu, H., Ramasco, J. J., & Vespignani, A. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0906910106 · Cited by 1,380
Quantifying the Impact of Human Mobility on Malaria
Wesolowski, A., Eagle, N., Tatem, A. J., Smith, D. L., Noor, A. M., Snow, R. W., & Buckee, C. O. (2012) · Science · doi:10.1126/science.1223467 · Cited by 992
Metadata
- Authors
- Longini, I. M., Nizam, A., Xu, S., Ungchusak, K., Hanshaoworakul, W., Cummings, D. A. T., & Halloran, M. E.
- Venue
- Science
- Published
- 2005-08-12
- Volume
- 309
- Issue
- 5737
- Pages
- 1083-1087
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2162707016
- Cited by
- 1,163
- References
- 25
- FWCI
- 60.20
- Type
- journal article
- Language
- en
- Open access
- closed
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- Longini, I. M., Nizam, A., Xu, S., Ungchusak, K., Hanshaoworakul, W., Cummings, D. A. T., & Halloran, M. E. (2005). Containing Pandemic Influenza at the Source. Science. https://doi.org/10.1126/science.1115717
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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