The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
A Synthetic Maternal-Effect Selfish Genetic Element Drives Population Replacement in Drosophila
Abstract
One proposed strategy for controlling the transmission of insect-borne pathogens uses a drive mechanism to ensure the rapid spread of transgenes conferring disease refractoriness throughout wild populations. Here, we report the creation of maternal-effect selfish genetic elements in Drosophila that drive population replacement and are resistant to recombination-mediated dissociation of drive and disease refractoriness functions. These selfish elements use microRNA-mediated silencing of a maternally expressed gene essential for embryogenesis, which is coupled with early zygotic expression of a rescuing transgene.
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Cites
Mosquito behavior and vector control
Pates, H., & Curtis, C. (2005) · Annual Review of Entomology · doi:10.1146/annurev.ento.50.071803.130439 · Cited by 403
Speciation Within Anopheles gambiae -- the Glass Is Half Full
della Torre, A., Costantini, C., Besansky, N. J., Caccone, A., Petrarca, V., Powell, J. R., & Coluzzi, M. (2002) · Science · doi:10.1126/science.1078170 · Cited by 229
Cited by
Malaria: progress, perils, and prospects for eradication
Greenwood, B. M., Fidock, D. A., Kyle, D. E., Kappe, S. H. I., Alonso, P. L., Collins, F. H., & Duffy, P. E. (2008) · Journal of Clinical Investigation · doi:10.1172/jci33996 · Cited by 709
Selfish genetic elements, genetic conflict, and evolutionary innovation
Werren, J. H. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1102343108 · Cited by 444
Mosquito ecology and control of malaria
Godfray, H. C. J. (2013) · Journal of Animal Ecology · doi:10.1111/1365-2656.12003 · Cited by 84
Loss of Fis1 impairs proteostasis during skeletal muscle aging in Drosophila
Lee, T., Chen, P., Su, M. P., Li, J., Chang, Y., Liu, R., Juan, H., Yang, J., Chan, S., Tsai, Y., et al. (2021) · Aging Cell · doi:10.1111/acel.13379 · Cited by 27
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Metadata
- Authors
- Chen, C.-H., Huang, H., Ward, C. M., Su, J. T., Schaeffer, L. V., Guo, M., & Hay, B. A.
- Venue
- Science
- Published
- 2007-04-27
- Volume
- 316
- Issue
- 5824
- Pages
- 597-600
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2004868096
- Cited by
- 318
- References
- 2
- FWCI
- 6.94
- Type
- journal article
- Language
- en
- Open access
- closed
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- Chen, C.-H., Huang, H., Ward, C. M., Su, J. T., Schaeffer, L. V., Guo, M., & Hay, B. A. (2007). A Synthetic Maternal-Effect Selfish Genetic Element Drives Population Replacement in Drosophila. Science. https://doi.org/10.1126/science.1138595
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
