The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Genome Sequence of Aedes aegypti , a Major Arbovirus Vector
Open accessAbstract
We present a draft sequence of the genome of Aedes aegypti , the primary vector for yellow fever and dengue fever, which at ∼1376 million base pairs is about 5 times the size of the genome of the malaria vector Anopheles gambiae . Nearly 50% of the Ae. aegypti genome consists of transposable elements. These contribute to a factor of ∼4 to 6 increase in average gene length and in sizes of intergenic regions relative to An. gambiae and Drosophila melanogaster . Nonetheless, chromosomal synteny is generally maintained among all three insects, although conservation of orthologous gene order is higher (by a factor of ∼2) between the mosquito species than between either of them and the fruit fly. An increase in genes encoding odorant binding, cytochrome P450, and cuticle domains relative to An. gambiae suggests that members of these protein families underpin some of the biological differences between the two mosquito species.
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Cites
Comparative Genome and Proteome Analysis of Anopheles gambiae and Drosophila melanogaster
Zdobnov, E. M., von Mering, C., Letunic, I., Torrents, D., Suyama, M., Copley, R. R., Christophides, G. K., Thomasova, D., Holt, R. A., Subramanian, G. M., et al. (2002) · Science · doi:10.1126/science.1077061 · Cited by 553
Self-citation
Cited by
Global Spread and Persistence of Dengue
Kyle, J. L., & Harris, E. (2008) · Annual Review of Microbiology · doi:10.1146/annurev.micro.62.081307.163005 · Cited by 916
Malaria: progress, perils, and prospects for eradication
Greenwood, B. M., Fidock, D. A., Kyle, D. E., Kappe, S. H. I., Alonso, P. L., Collins, F. H., & Duffy, P. E. (2008) · Journal of Clinical Investigation · doi:10.1172/jci33996 · Cited by 709
Self-citationIntegration of mapped RNA-Seq reads into automatic training of eukaryotic gene finding algorithm
Lomsadze, A., Burns, P. D., & Borodovsky, M. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku557 · Cited by 612
Zdobnov, E. M., Tegenfeldt, F., Kuznetsov, D., Waterhouse, R. M., Simão, F. A., Ioannidis, P., Seppey, M., Loetscher, A., & Kriventseva, E. V. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkw1119 · Cited by 438
Self-citationOptimization of de novo transcriptome assembly from next-generation sequencing data
Surget-Groba, Y., & Montoya-Burgos, J. I. (2010) · Genome Research · doi:10.1101/gr.103846.109 · Cited by 339
Metadata
- Authors
- Nene, V., Wortman, J. R., Lawson, D., Haas, B., Kodira, C., Tu, Z. (., Loftus, B., Xi, Z., Megy, K., Grabherr, M., Ren, Q., Zdobnov, E. M., Lobo, N. F., Campbell, K. S., Brown, S. E., Bonaldo, M. F., Zhu, J., Sinkins, S. P., Hogenkamp, D. G., Amedeo, P., Arensburger, P., Atkinson, P. W., Bidwell, S., Biedler, J., Birney, E., Bruggner, R. V., Costas, J., Coy, M. R., Crabtree, J., Crawford, M., deBruyn, B., DeCaprio, D., Eiglmeier, K., Eisenstadt, E., El-Dorry, H., Gelbart, W. M., Gomes, S. L., Hammond, M., Hannick, L. I., Hogan, J. R., Holmes, M. H., Jaffe, D., Johnston, J. S., Kennedy, R. C., Koo, H., Kravitz, S., Kriventseva, E. V., Kulp, D., LaButti, K., Lee, E., Li, S., Lovin, D. D., Mao, C., Mauceli, E., Menck, C. F. M., Miller, J. R., Montgomery, P., Mori, A., Nascimento, A. L., Naveira, H. F., Nusbaum, C., O'Leary, S., Orvis, J., Pertea, M., Quesneville, H., Reidenbach, K. R., Rogers, Y.-H., Roth, C. W., Schneider, J. R., Schatz, M., Shumway, M., Stanke, M., Stinson, E. O., Tubio, J. M. C., VanZee, J. P., Verjovski-Almeida, S., Werner, D., White, O., Wyder, S., Zeng, Q., Zhao, Q., Zhao, Y., Hill, C. A., Raikhel, A. S., Soares, M. B., Knudson, D. L., Lee, N. H., Galagan, J., Salzberg, S. L., Paulsen, I. T., Dimopoulos, G., Collins, F. H., Birren, B., Fraser-Liggett, C. M., & Severson, D. W.
- Venue
- Science
- Published
- 2007-06-22
- Volume
- 316
- Issue
- 5832
- Pages
- 1718-1723
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2171158206
- Cited by
- 1,080
- References
- 1
- FWCI
- 78.75
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: Genome Sequence of Aedes aegypti , a Major Arbovirus Vector. https://app.cochat.ai/papers/10.1126/science.1138878
- The paper
- Nene, V., Wortman, J. R., Lawson, D., Haas, B., Kodira, C., Tu, Z. (., Loftus, B., Xi, Z., Megy, K., Grabherr, M., Ren, Q., Zdobnov, E. M., Lobo, N. F., Campbell, K. S., Brown, S. E., Bonaldo, M. F., Zhu, J., Sinkins, S. P., Hogenkamp, D. G., . . . Severson, D. W. (2007). Genome Sequence of Aedes aegypti , a Major Arbovirus Vector. Science. https://doi.org/10.1126/science.1138878
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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