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Programming DNA Tube Circumferences
Abstract
Synthesizing molecular tubes with monodisperse, programmable circumferences is an important goal shared by nanotechnology, materials science, and supermolecular chemistry. We program molecular tube circumferences by specifying the complementarity relationships between modular domains in a 42-base single-stranded DNA motif. Single-step annealing results in the self-assembly of long tubes displaying monodisperse circumferences of 4, 5, 6, 7, 8, 10, or 20 DNA helices.
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“Robust, rigid DNA tiles with programmable “sticky ends” have been made using double-crossover (DX),141 triple-crossover (TX),142 and single-stranded tile (SST)143 motifs and used for a variety of algorithmic self-assembly experiments.”
From Emerging Approaches to DNA Data Storage: Challenges and Prospects (2022) · cites this paper as [143]
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Metadata
- Authors
- Yin, P., Hariadi, R. F., Sahu, S., Choi, H. M. T., Park, S. H., LaBean, T. H., & Reif, J. H.
- Affiliations
- California Institute of Technology (US)
- Corresponding author
- Yin, Peng
- Park, Sung Ha
- Venue
- Science
- Published
- 2008-08-08
- Volume
- 321
- Issue
- 5890
- Pages
- 824-826
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2122742537
- Cited by
- 486
- References
- 26
- Citations by year
- 2026: 8 · 2025: 18 · 2024: 18 · 2023: 24 · 2022: 33 · 2021: 25 · 2020: 35 · 2019: 29 · 2018: 34 · 2017: 37 · 2016: 37 · 2015: 40 · 2014: 31 · 2013: 33 · 2012: 19
- FWCI
- 8.88
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Advanced biosensing and bioanalysis techniques
- Physical Sciences › Materials Science › Biomaterials › Supramolecular Self-Assembly in Materials
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › DNA and Nucleic Acid Chemistry
- Keywords
- DNA nanotechnology, molecular tubes, single-stranded DNA, DNA self-assembly, annealing
- MeSH terms
- DNA, DNA, Single-Stranded, Nucleic Acid Conformation, Microscopy, Atomic Force, Nanotechnology, Nanotubes
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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