Promoting Axon Regeneration in the Adult CNS by Modulation of the PTEN/mTOR Pathway

Park, Kevin Kyungsuk, Liu, Kai, Hu, Yang, Smith, Patrice D., Wang, Chen, Cai, Bin, Xu, Bengang, Connolly, Lauren, Kramvis, Ioannis, Sahin, Mustafa, He, Zhigang·2008·Science

DOI 10.1126/science.1161566

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Florence Cordier, Alain F. Chaffotte, Elouan Terrien, Christophe J. N. Prehaud, François‐Xavier Theillet, Muriel Delepierre, Monique Lafon, Henri C. BUC, Nicolas Wolff · 2012 · Journal of the American Chemical Society
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Aruni S. Arachchige Don, Chi Kwan Tsang, Tatiana M. Kazdoba, Gabriella D’Arcangelo, Wise Young, Xi Zheng · 2012 · Drug Discovery Today
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Ping Yang, Zhong Yang · 2011 · Journal of the Neurological Sciences
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Saloni T. Mehta, Xueting Luo, Kevin Kyungsuk Park, John L. Bixby, Vance Lemmon · 2016 · Experimental Neurology
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Camila Marques Freria, Erna A. van Niekerk, Armin Blesch, Paul Lu · 2021 · Cells
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Jaewon Park, Sun-Ja Kim, Su Inn Park, Yoonsuck Choe, Jianrong Li, Arum Han · 2013 · Journal of Neuroscience Methods
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Dongsheng Wu, Michelle C. Klaw, Theresa M. Connors, Nikolai G. Kholodilov, Robert E. Burke, Veronica J. Tom · 2015 · Journal of Neuroscience
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Kimberly J. Christie, Douglas William Zochodne · 2013 · Neuroscience
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Arul Duraikannu, Anand Krishnan, Ambika Chandrasekhar, Douglas William Zochodne · 2019 · Frontiers in Cellular Neuroscience
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Morquette, B, Morquette, P, Agostinone, J, Feinstein, E, McKinney, R A, Kolta, A, Di Polo, A · 2015 · Cell Death & Differentiation
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Ohtake, Yosuke, Wong, Daniella, Abdul-Muneer, P. M., Selzer, Michael E., Li, Shuxin · 2016 · Scientific Reports
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Caitlin E. Hill · 2016 · Neuroscience Letters
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Kimberly Kinga Gokoffski, Micalla G. Peng, Basheer F. Alas, Phillip Lam · 2019 · Current Opinion in Neurology
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Steven J. Jacques, Zubair Ahmed, Anna Forbes, Michael R. Douglas, Vasanthy Vigenswara, Martin Berry, Ann Logan · 2012 · Molecular and Cellular Neuroscience
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Haoliang Huang, Linqing Miao, Feisi Liang, Xiaodong Liu, Lin Xu, Xiuyin Teng, Wang Qizhao, William H. Ridder, Kenneth S. Shindler, Yang Sun et al. · 2017 · Cell Death and Disease
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Jörg Ruschel, Frank Bradke · 2017 · Experimental Neurology
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Fatima M. Nathan, Yosuke Ohtake, Shuo Wang, Xinpei Jiang, Armin Sami, Hua Guo, Feng‐Quan Zhou, Shuxin Li · 2020 · Molecular Therapy
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Xiaojun Li, Angelika Doetzlhofer · 2020 · Proceedings of the National Academy of Sciences
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Kevin Yang Zhang, Caitlyn Tuffy, Joseph L. Mertz, Sarah E. Quillen, Laurence Wechsler, Harry A. Quigley, Donald J. Zack, Thomas V. Johnson · 2020 · Stem Cell Reports
Rapamycin suppresses axon sprouting by somatostatin interneurons in a mouse model of temporal lobe epilepsy
Paul S. Buckmaster, Xiling Wen · 2011 · Epilepsia
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Xuewei Wang, Shu-Guang Yang, Chi Zhang, Ming-Wen Hu, Jiang X. Qian, Jinjin Ma, Yingchi Zhang, Bin-Bin Yang, Yi‐Lan Weng, Guo‐li Ming et al. · 2020 · Cell Reports
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Yunsong Zhang, Qian Zhao, Qianqian Chen, Lingchi Xu, Sheng Yi · 2022 · Molecular Neurobiology
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Lynn Usher, Andrea L. Johnstone, Ali Ertürk, Ying Jia Hu, Dinara Strikis, Ina B. Wanner, Sanne Moorman, Jae-Wook Lee, Jaeki Min, Hyung‐Ho Ha et al. · 2010 · Journal of Neuroscience
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Martín Roffé, Glaucia N. M. Hajj, Hatylas F. Z de Azevedo, Viviane S. Alves, Beatriz A. Castilho · 2013 · Journal of Biological Chemistry
Molecular targets for axon regeneration: focus on the intrinsic pathways
Simone Di Giovanni · 2009 · Expert Opinion on Therapeutic Targets
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Yuichi Sekine, Alexander T. Lin-Moore, Devon M. Chenette, Xingxing Wang, Zhaoxin Jiang, William B.J. Cafferty, Marc Hammarlund, Stephen M. Strittmatter · 2018 · Cell Reports
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Kai Zhou, Wei Wei, Dan Yang, Hui Zhang, Wei Yang, Yunpeng Zhang, Yingnan Nie, Mingming Hao, Peng‐Cheng Wang, Hang Ruan et al. · 2024 · Nature Communications
Genome-wide gene expression and promoter binding analysis identifies NFIL3 as a repressor of C/EBP target genes in neuronal outgrowth
Harold D. MacGillavry, Jochem Cornelis, Loek R. van der Kallen, Marion J.M. Bergamin-Sassen, Joost Verhaagen, August Benjamin Smit, Ronald E. van Kesteren · 2010 · Molecular and Cellular Neuroscience
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Rafael Pulido · 2015 · Methods
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Weitao Chen, Na Lu, Yue Ding, Yuan Wang, Leung Ting Chan, Xu Wang, Xin Gao, Songshan Jiang, Kai Liu · 2016 · eNeuro
Determinants of Axon Growth, Plasticity, and Regeneration in the Context of Spinal Cord Injury
Angela R. Filous, Jan Markus Schwab · 2017 · American Journal Of Pathology
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Chenying Guo, Kin‐Sang Cho, Yingqian Li, K. T. Tchedre, Christian Antolik, Jie Ma, Justin Chew, Tor Paaske Utheim, Xizhong Huang, Honghua Yu et al. · 2018 · Scientific Reports
Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model
Jinghuan Wang, Dong Wan, Guoran Wan, Jianghong Wang, Junhui Zhang, Huifeng Zhu · 2019 · Annals of Translational Medicine
Retinal Ganglion Cell Gene Therapy and Visual System Repair
Mats Hellström, Alan R. Harvey · 2011 · Current Gene Therapy
Scaffolds and stem cells: delivery of cell transplants for retinal degenerations
Karl E. Kador, Jeffrey Louis Goldberg · 2012 · Expert Review of Ophthalmology
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Annemarie Heskamp, Marco Leibinger, Anastasia Andreadaki, Philipp Gobrecht, Heike Diekmann, Dietmar Fischer · 2013 · Neurobiology of Disease
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Meifan Chen, Binhai Zheng · 2014 · Trends in Neurosciences
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Hai Li, Takaaki Kuwajima, Derek H. Oakley, Elena Nikulina, Jianwei Hou, Wan Seok Yang, Emily R. Lowry, Nuno Jorge Lamas, Mackenzie Weygandt Mathis, Gist F. Croft et al. · 2016 · Cell Reports
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Meital Oren‐Suissa, Tamar Gattegno, Veronika Kravtsov, Benjamin Podbilewicz · 2017 · Genetics
Stimulation-dependent remodeling of the corticospinal tract requires reactivation of growth-promoting developmental signaling pathways
Neela Zareen, Shahid Dodson, Kristine Armada, Rahma Awad, Nadia Sultana, Erina Hara, Heather Alexander, John H. Martin · 2018 · Experimental Neurology
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Yuanquan Song, David W. Sretavan, Ernesto A. Salegio, Jim Berg, Xi Huang, Tong Cheng, Xin Xiong, Shan Meltzer, Chun Han, Trong-Tuong Nguyen et al. · 2015 · Nature Neuroscience
Crystallins in Retinal Ganglion Cell Survival and Regeneration
Natik Piri, Jacky M. K. Kwong, Joseph Caprioli · 2013 · Molecular Neurobiology
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Pooja Teotia, Matthew J. Van Hook, Christopher Wichman, R. Rand Allingham, Michael A. Hauser, Iqbal Ahmad · 2017 · Stem Cells
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Joana Galvão, Keiichiro Iwao, Akintomide Apara, Yan Wang, Masoumeh Ashouri, Tejas Nimish Shah, Murray G. Blackmore, Noelia J. Kunzevitzky, Darcie L. Moore, Jeffrey Louis Goldberg · 2018 · Investigative Ophthalmology & Visual Science
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Bart Nieuwenhuis, Amanda C. Barber, Rachel S Evans, Craig S. Pearson, Joachim Fuchs, Amy R MacQueen, Susan van Erp, Barbara Haenzi, Lianne A. Hulshof, Andrew Osborne et al. · 2020 · EMBO Molecular Medicine
Axon Regeneration in C. elegans
Marc Hammarlund, Yi-Shi Jin · 2014 · Current Opinion in Neurobiology
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Patrick Cooke, Haley N. Janowitz, Sarah Dougherty · 2022 · Frontiers in Cellular Neuroscience
Transcriptional profiling of intrinsic PNS factors in the postnatal mouse
Robin P. Smith, Jessica K. Lerch, José R. Pardinas, William Buchser, John L. Bixby, Vance Lemmon · 2010 · Molecular and Cellular Neuroscience
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Marc A. DePaul, Ching‐Yi Lin, Jerry Silver, Yu‐Shang Lee · 2017 · Scientific Reports
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Theresa C. Sutherland, Cédric G. Geoffroy · 2020 · Frontiers in Cell and Developmental Biology
PTEN inhibition enhances neurite outgrowth in human embryonic stem cell–derived neuronal progenitor cells
Lindsey A. Wyatt, Marie T. Filbin, Hans S. Keirstead · 2014 · The Journal of Comparative Neurology
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Billy Y. B. Lau, Stephanie M. Fogerson, Rylie B. Walsh, Jennifer R. Morgan · 2013 · Experimental Neurology
In vitro models of axon regeneration
Hassan Al‐Ali, Samuel R. Beckerman, John L. Bixby, Vance Lemmon · 2016 · Experimental Neurology
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Jung Eun Shin, Yongcheol Cho · 2017 · Molecules and Cells
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Almir Jordão da Silva‐Junior, Louise Alessandra Mesentier-Louro, Gabriel Nascimento‐dos‐Santos, Leandro Coelho Teixeira‐Pinheiro, Juliana Ferreira Vasques, Luiza Chimeli-Ormonde, Victor Bodart‐Santos, Luiza Rachel Pinheiro de Carvalho, Marcelo F. Santiago, Rosalia Méndez‐Otero · 2021 · Stem Cell Research & Therapy
Retinal Ganglion Cell Transplantation: Approaches for Overcoming Challenges to Functional Integration
Kevin Yang Zhang, Erika A. Aguzzi, Thomas V. Johnson · 2021 · Cells
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Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization
J. Wu, Sarah E. McCallum, S.D. Glick, Y. Huang · 2010 · Neuroscience