The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Multiscale Mechanics of Fibrin Polymer: Gel Stretching with Protein Unfolding and Loss of Water
Open accessAbstract
<< Focusing on Fibrin: Vascular injury initiates biochemical reactions that cause the blood protein, fibrin, to polymerize and help to stop bleeding and support wound healing. Fibrin can also be a scaffold for thrombi that lead to cardiovascular diseases. To maintain homeostasis, fibrin clots must be stiff, plastic, and, so that the network can be decompsed, permeable. Brown et al. (p. 741 ) investigated the behavior of fibrin clots at the macroscopic, single-fiber, and molecular scale. At relatively low strains, fibers aligned and formed bundles, and at higher strains, protein unfolding occurred. An integrated model provides a molecular basis for fibrin elasticity and extensibility.
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Citations
Cites
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
Discher, D. E., Janmey, P., & Wang, Y.-L. (2005) · Science · doi:10.1126/science.1116995 · Cited by 6,382
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Cited by
Effects of extracellular matrix viscoelasticity on cellular behaviour
Chaudhuri, O., Cooper-White, J., Janmey, P. A., Mooney, D. J., & Shenoy, V. B. (2020) · Nature · doi:10.1038/s41586-020-2612-2 · Cited by 2,224
Cines, D. B., Lebedeva, T., Nagaswami, C., Hayes, V., Massefski, W., Litvinov, R. I., Rauova, L., Lowery, T. J., & Weisel, J. W. (2014) · Blood · doi:10.1182/blood-2013-08-523860 · Cited by 420
Self-citationZhang, K., Feng, Q., Fang, Z., Gu, L., & Bian, L. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00071 · Cited by 394
Design and applications of man-made biomimetic fibrillar hydrogels
Prince, E., & Kumacheva, E. (2019) · Nature Reviews Materials · doi:10.1038/s41578-018-0077-9 · Cited by 379
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Metadata
- Authors
- Brown, A. E. X., Litvinov, R. I., Discher, D. E., Purohit, P. K., & Weisel, J. W.
- Venue
- Science
- Published
- 2009-08-07
- Volume
- 325
- Issue
- 5941
- Pages
- 741-744
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2146012199
- Cited by
- 416
- References
- 1
- FWCI
- 17.79
- Type
- journal article
- Language
- en
- Open access
- green
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- Brown, A. E. X., Litvinov, R. I., Discher, D. E., Purohit, P. K., & Weisel, J. W. (2009). Multiscale Mechanics of Fibrin Polymer: Gel Stretching with Protein Unfolding and Loss of Water. Science. https://doi.org/10.1126/science.1172484
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
