Viscoelastic hydrogels for 3D cell culture

Atomic Force Microscope

Binnig, G. K., Quate, C. F., & Gerber, C. (1986) · Physical Review Letters · doi:10.1103/physrevlett.56.930 · Cited by 14,795 · see citing works

Matrix elasticity directs stem cell lineage specification

Engler, A. J., Sen, S., Sweeney, H. L., & Discher, D. E. (2006) · Cell · doi:10.1016/j.cell.2006.06.044 · Cited by 13,915 · see citing works

The Theory of Polymer Dynamics

Marrucci, G. (1987) · Journal of Non-Newtonian Fluid Mechanics · doi:10.1016/0377-0257(87)85036-x · Cited by 10,050 · see citing works

The theory of polymer dynamics

Doi, M., & Edwards, S. F. (1986) · Cited by 8,964 · see citing works

Tissue Cells Feel and Respond to the Stiffness of Their Substrate

Discher, D. E., Janmey, P., & Wang, Y.-L. (2005) · Science · doi:10.1126/science.1116995 · Cited by 6,382 · see citing works

Biomechanics. Mechanical Properties of Living Tissues

Fung, Y. C., & Skalak, R. (1982) · Journal of Applied Mechanics · doi:10.1115/1.3162171 · Cited by 6,045 · see citing works

Hydrogels for Tissue Engineering

Lee, K. Y., & Mooney, D. J. (2001) · Chemical Reviews · doi:10.1021/cr000108x · Cited by 5,295 · see citing works

Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering

Lutolf, M. P., & Hubbell, J. A. (2005) · Nature Biotechnology · doi:10.1038/nbt1055 · Cited by 4,551 · see citing works

Tensional homeostasis and the malignant phenotype

Paszek, M. J., Zahir, N., Johnson, K. R., Lakins, J. N., Rozenberg, G. I., Gefen, A., Reinhart-King, C. A., Margulies, S. S., Dembo, M., Boettiger, D., et al. (2005) · Cancer Cell · doi:10.1016/j.ccr.2005.08.010 · Cited by 3,941 · see citing works

Force measurements with the atomic force microscope: Technique, interpretation and applications

Butt, H., Cappella, B., & Kappl, M. (2005) · Surface Science Reports · doi:10.1016/j.surfrep.2005.08.003 · Cited by 3,706 · see citing works

Cell locomotion and focal adhesions are regulated by substrate flexibility.

Pelham, R., & Wang, Y.-L. (1997) · Proceedings of the National Academy of Sciences of the United States of America · doi:10.1073/pnas.94.25.13661 · Cited by 3,156 · see citing works

Taking Cell-Matrix Adhesions to the Third Dimension

Cukierman, E., Pankov, R., Stevens, D. R., & Yamada, K. M. (2001) · Science · doi:10.1126/science.1064829 · Cited by 3,027 · see citing works

Hydrogels with tunable stress relaxation regulate stem cell fate and activity

Chaudhuri, O., Gu, L., Klumpers, D., Darnell, M., Bencherif, S. A., Weaver, J. C., Huebsch, N., Lee, H.-P., Lippens, E., Duda, G. N., et al. (2016) · Nature Materials · doi:10.1038/nmat4489 · Cited by 2,443 · see citing works

Alginate hydrogels as synthetic extracellular matrix materials

Rowley, J. A., Madlambayan, G., & Mooney, D. J. (1999) · Biomaterials · doi:10.1016/s0142-9612(98)00107-0 · Cited by 2,342 · see citing works

Local force and geometry sensing regulate cell functions

Vogel, V., & Sheetz, M. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1890 · Cited by 2,328 · see citing works

Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion

Yeung, T., Georges, P. C., Flanagan, L. A., Marg, B., Ortiz, M., Funaki, M., Zahir, N., Ming, W., Weaver, V., & Janmey, P. A. (2005) · Cell Motility and the Cytoskeleton · doi:10.1002/cm.20041 · Cited by 2,325 · see citing works

Hyaluronic Acid Hydrogels for Biomedical Applications

Burdick, J. A., & Prestwich, G. D. (2011) · Advanced Materials · doi:10.1002/adma.201003963 · Cited by 2,150 · see citing works

A practical guide to hydrogels for cell culture

Caliari, S. R., & Burdick, J. A. (2016) · Nature Methods · doi:10.1038/nmeth.3839 · Cited by 2,075 · see citing works

Biomechanics

Fung, Y. C. (1993) · Springer eBooks · doi:10.1007/978-1-4757-2257-4 · Cited by 2,052 · see citing works

Nuclear Lamin-A Scales with Tissue Stiffness and Enhances Matrix-Directed Differentiation

Swift, J., Ivanovska, I. L., Buxboim, A., Harada, T., Dingal, P. C. D. P., Pinter, J., Pajerowski, J. D., Spinler, K. R., Shin, J., Tewari, M., et al. (2013) · Science · doi:10.1126/science.1240104 · Cited by 1,998 · see citing works

Mechanotransduction at a distance: mechanically coupling the extracellular matrix with the nucleus

Wang, N., Tytell, J. D., & Ingber, D. E. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2594 · Cited by 1,768 · see citing works

Myotubes differentiate optimally on substrates with tissue-like stiffness

Engler, A. J., Griffin, M. A., Sen, S., Bönnemann, C. G., Sweeney, H. L., & Discher, D. E. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200405004 · Cited by 1,743 · see citing works

Integrin ligands at a glance

Humphries, J. D., Byron, A., & Humphries, M. J. (2006) · Journal of Cell Science · doi:10.1242/jcs.03098 · Cited by 1,711 · see citing works

Nonlinear elasticity in biological gels

Storm, C., Pastore, J. J., MacKintosh, F. C., Lubensky, T. C., & Janmey, P. A. (2005) · Nature · doi:10.1038/nature03521 · Cited by 1,707 · see citing works

Optical Measurements of Frequency-Dependent Linear Viscoelastic Moduli of Complex Fluids

Mason, T. G., & Weitz, D. A. (1995) · Physical Review Letters · doi:10.1103/physrevlett.74.1250 · Cited by 1,699 · see citing works

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

Gilbert, P. M., Havenstrite, K. L., Magnusson, K. E. G., Sacco, A., Leonardi, N. A., Kraft, P., Nguyen, N. K., Thrun, S., Lutolf, M. P., & Blau, H. M. (2010) · Science · doi:10.1126/science.1191035 · Cited by 1,587 · see citing works

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

Huebsch, N., Arany, P. R., Mao, A. S., Shvartsman, D. E., Ali, O. A., Bencherif, S. A., Rivera‐Feliciano, J., & Mooney, D. J. (2010) · Nature Materials · doi:10.1038/nmat2732 · Cited by 1,572 · see citing works

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics

Grashoff, C., Hoffman, B. D., Brenner, M. D., Zhou, R., Parsons, M., Yang, M. T., McLean, M. A., Sligar, S. G., Chen, C. S., Ha, T., et al. (2010) · Nature · doi:10.1038/nature09198 · Cited by 1,549 · see citing works

COLLAGEN SUBSTRATA FOR STUDIES ON CELL BEHAVIOR

Elsdale, T., & Bard, J. (1972) · The Journal of Cell Biology · doi:10.1083/jcb.54.3.626 · Cited by 1,529 · see citing works

Stretching Single Talin Rod Molecules Activates Vinculin Binding

Hernández, A. E. D. R., Pérez‐Jiménez, R., Liu, R., Roca‐Cusachs, P., Fernández, J. M., & Sheetz, M. P. (2009) · Science · doi:10.1126/science.1162912 · Cited by 1,492 · see citing works

Stresses at the Cell-to-Substrate Interface during Locomotion of Fibroblasts

Dembo, M., & Wang, Y. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77386-8 · Cited by 1,273 · see citing works

Elastic Behavior of Cross-Linked and Bundled Actin Networks

Gardel, M. L., Shin, J. H., MacKintosh, F. C., Mahadevan, L., Matsudaira, P. T., & Weitz, D. A. (2004) · Science · doi:10.1126/science.1095087 · Cited by 1,256 · see citing works

Multi-scale multi-mechanism design of tough hydrogels: building dissipation into stretchy networks

Zhao, X. (2013) · Soft Matter · doi:10.1039/c3sm52272e · Cited by 1,254 · see citing works

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

Khetan, S., Güvendiren, M., Legant, W. R., Cohen, D. M., Chen, C. S., & Burdick, J. A. (2013) · Nature Materials · doi:10.1038/nmat3586 · Cited by 1,171 · see citing works

Activation of Integrin Function by Nanopatterned Adhesive Interfaces

Arnold, M., Cavalcanti‐Adam, E. A., Glass, R., Blümmel, J., Eck, W., Kantlehner, M., Kessler, H., & Spatz, J. P. (2004) · ChemPhysChem · doi:10.1002/cphc.200301014 · Cited by 1,165 · see citing works

Substrate Compliance versus Ligand Density in Cell on Gel Responses

Engler, A. J., Bačáková, L., Newman, C., Hategan, A. P., Griffin, M. A., & Discher, D. E. (2004) · Biophysical Journal · doi:10.1016/s0006-3495(04)74140-5 · Cited by 1,127 · see citing works

Of Extracellular Matrix, Scaffolds, and Signaling: Tissue Architecture Regulates Development, Homeostasis, and Cancer

Nelson, C. M., & Bissell, M. J. (2006) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.22.010305.104315 · Cited by 1,121 · see citing works

Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.

PETERSEN, O. W., Rønnov‐Jessen, L., Howlett, A. R., & Bissell, M. J. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.19.9064 · Cited by 1,096 · see citing works

Fibroblast Adaptation and Stiffness Matching to Soft Elastic Substrates

Solon, J., Levental, I., Sengupta, K., Georges, P. C., & Janmey, P. A. (2007) · Biophysical Journal · doi:10.1529/biophysj.106.101386 · Cited by 1,026 · see citing works

Cell adhesion and motility depend on nanoscale RGD clustering

Maheshwari, G., Brown, G., Lauffenburger, D. A., Wells, A. H., & Griffith, L. G. (2000) · Journal of Cell Science · doi:10.1242/jcs.113.10.1677 · Cited by 951 · see citing works

Traction Dynamics of Filopodia on Compliant Substrates

Chan, C. E., & Odde, D. J. (2008) · Science · doi:10.1126/science.1163595 · Cited by 942 · see citing works

Mechanics, malignancy, and metastasis: The force journey of a tumor cell

Kumar, S., & Weaver, V. M. (2009) · Cancer and Metastasis Reviews · doi:10.1007/s10555-008-9173-4 · Cited by 930 · see citing works

Soft biological materials and their impact on cell function

Levental, I., Georges, P. C., & Janmey, P. A. (2006) · Soft Matter · doi:10.1039/b610522j · Cited by 908 · see citing works

Substrate stress relaxation regulates cell spreading

Chaudhuri, O., Gu, L., Darnell, M., Klumpers, D. D., Bencherif, S. A., Weaver, J. C., Huebsch, N., & Mooney, D. J. (2015) · Nature Communications · doi:10.1038/ncomms7365 · Cited by 887 · see citing works

Particle Tracking Microrheology of Complex Fluids

Mason, T. G., Ganesan, K., van Zanten, J. H., Wirtz, D., & Kuo, S. C. (1997) · Physical Review Letters · doi:10.1103/physrevlett.79.3282 · Cited by 872 · see citing works

Solid stress inhibits the growth of multicellular tumor spheroids

Helmlinger, G., Netti, P. A., Lichtenbeld, H. C., Melder, R. J., & Jain, R. K. (1997) · Nature Biotechnology · doi:10.1038/nbt0897-778 · Cited by 859 · see citing works

Hydrogel properties influence ECM production by chondrocytes photoencapsulated in poly(ethylene glycol) hydrogels

Bryant, S. J., & Anseth, K. S. (2002) · Journal of Biomedical Materials Research · doi:10.1002/jbm.1217 · Cited by 845 · see citing works

Measuring the viscoelastic properties of human platelets with the atomic force microscope

Radmacher, M., Fritz, M., Kacher, C. M., Cleveland, J. P., & Hansma, P. K. (1996) · Biophysical Journal · doi:10.1016/s0006-3495(96)79602-9 · Cited by 839 · see citing works

Mechanotransduction in development: a growing role for contractility

Wozniak, M. A., & Chen, C. S. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2592 · Cited by 821 · see citing works

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

Chaudhuri, O., Koshy, S. T., Branco da Cunha, C., Shin, J.-W., Verbeke, C. S., Allison, K. H., & Mooney, D. J. (2014) · Nature Materials · doi:10.1038/nmat4009 · Cited by 820 · see citing works

Measurement of Local Viscoelasticity and Forces in Living Cells by Magnetic Tweezers

Bausch, A. R., Möller, W., & Sackmann, E. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77225-5 · Cited by 808 · see citing works

The design of reversible hydrogels to capture extracellular matrix dynamics

Rosales, A. M., & Anseth, K. S. (2016) · Nature Reviews Materials · doi:10.1038/natrevmats.2015.12 · Cited by 770 · see citing works

Neurite branching on deformable substrates

Flanagan, L. A., Ju, Y. S., Marg, B., Osterfield, M., & Janmey, P. A. (2002) · Neuroreport · doi:10.1097/00001756-200212200-00007 · Cited by 759 · see citing works

Microrheology of Human Lung Epithelial Cells Measured by Atomic Force Microscopy

Alcaraz, J., Buscemi, L., Grabulosa, M., Trepat, X., Fabry, B., Farré, R., & Navajas, D. (2003) · Biophysical Journal · doi:10.1016/s0006-3495(03)75014-0 · Cited by 745 · see citing works

Adaptable Hydrogel Networks with Reversible Linkages for Tissue Engineering

Wang, H., & Heilshorn, S. C. (2015) · Advanced Materials · doi:10.1002/adma.201501558 · Cited by 723 · see citing works

Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering

Mann, B. K., Gobin, A. S., Tsai, A. T., Schmedlen, R. H., & West, J. L. (2001) · Biomaterials · doi:10.1016/s0142-9612(01)00051-5 · Cited by 705 · see citing works

Cell-mediated fibre recruitment drives extracellular matrix mechanosensing in engineered fibrillar microenvironments

Baker, B. M., Trappmann, B., Wang, W. Y., Sakar, M. S., Kim, I. L., Shenoy, V. B., Burdick, J. A., & Chen, C. S. (2015) · Nature Materials · doi:10.1038/nmat4444 · Cited by 556 · see citing works

Cell‐Responsive Synthetic Hydrogels

Lütolf, M. P., Raeber, G. P., Zisch, A. H., Tirelli, N., & Hubbell, J. A. (2003) · Advanced Materials · doi:10.1002/adma.200304621 · Cited by 526 · see citing works

Mammary Gland ECM Remodeling, Stiffness, and Mechanosignaling in Normal Development and Tumor ProgressionPreprint

Schedin, P. S., & Keely, P. J. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003228 · Cited by 523 · see citing works

Scanning Probe-Based Frequency-Dependent Microrheology of Polymer Gels and Biological Cells

Mahaffy, R. E., Shih, C.-K. K., MacKintosh, F. C., & Käs, J. A. (2000) · Physical Review Letters · doi:10.1103/physrevlett.85.880 · Cited by 509 · see citing works

Mimicking biological functionality with polymers for biomedical applications

Green, J. J., & Elisseeff, J. H. (2016) · Nature · doi:10.1038/nature21005 · Cited by 494 · see citing works

Viscoelastic Properties of Living Embryonic Tissues: a Quantitative Study

Forgács, G., Foty, R. A., Shafrir, Y., & Steinberg, M. S. (1998) · Biophysical Journal · doi:10.1016/s0006-3495(98)77932-9 · Cited by 485 · see citing works

Mechanical Properties of Cellularly Responsive Hydrogels and Their Experimental Determination

Kloxin, A. M., Kloxin, C. J., Bowman, C. N., & Anseth, K. S. (2010) · Advanced Materials · doi:10.1002/adma.200904179 · Cited by 477 · see citing works

The influence of substrate creep on mesenchymal stem cell behaviour and phenotype

Cameron, A. R., Frith, J. E., & Cooper-White, J. J. (2011) · Biomaterials · doi:10.1016/j.biomaterials.2011.04.003 · Cited by 428 · see citing works

Two-dimensional mechanical properties of rabbit skin—I. Experimental system

Lanir, Y., & Fung, Y. C. (1974) · Journal of Biomechanics · doi:10.1016/0021-9290(74)90067-0 · Cited by 425 · see citing works

Cell-Cycle Control by Physiological Matrix Elasticity and In Vivo Tissue Stiffening

Klein, E. A., Yin, L., Kothapalli, D., Castagnino, P. A., Byfield, F. J., Xu, T., Levental, I., Hawthorne, E. A., Janmey, P. A., & Assoian, R. K. (2009) · Current Biology · doi:10.1016/j.cub.2009.07.069 · Cited by 421 · see citing works

Biophysically Defined and Cytocompatible Covalently Adaptable Networks as Viscoelastic 3D Cell Culture Systems

McKinnon, D. D., Domaille, D. W., Cha, J. N., & Anseth, K. S. (2013) · Advanced Materials · doi:10.1002/adma.201303680 · Cited by 417 · see citing works

Multiscale Mechanics of Fibrin Polymer: Gel Stretching with Protein Unfolding and Loss of Water

Brown, A. E., Игоревич, Л. Р., Discher, D. E., Purohit, P. K., & Weisel, J. W. (2009) · Science · doi:10.1126/science.1172484 · Cited by 416 · see citing works

Reversible stress softening of actin networks

Chaudhuri, O., Parekh, S. H., & Fletcher, D. A. (2007) · Nature · doi:10.1038/nature05459 · Cited by 407 · see citing works

Biomaterials and emerging anticancer therapeutics: engineering the microenvironment

Gu, L., & Mooney, D. J. (2016) · Nature Reviews Cancer · doi:10.1038/nrc.2015.3 · Cited by 407 · see citing works

Stress-stiffening-mediated stem-cell commitment switch in soft responsive hydrogels

Das, R. K., Gocheva, V., Hammink, R., Zouani, O. F., & Rowan, A. E. (2015) · Nature Materials · doi:10.1038/nmat4483 · Cited by 407 · see citing works

Three-dimensional growth and function of neural tissue in degradable polyethylene glycol hydrogels

Mahoney, M. J., & Anseth, K. S. (2005) · Biomaterials · doi:10.1016/j.biomaterials.2005.11.007 · Cited by 377 · see citing works

Stress-relaxation behavior in gels with ionic and covalent crosslinks

Zhao, X., Huebsch, N., Mooney, D. J., & Suo, Z. (2010) · Journal of Applied Physics · doi:10.1063/1.3343265 · Cited by 375 · see citing works

Determining Microscopic Viscoelasticity in Flexible and Semiflexible Polymer Networks from Thermal Fluctuations

Schnurr, B., Gittes, F., MacKintosh, F. C., & Schmidt, C. F. (1997) · Macromolecules · doi:10.1021/ma970555n · Cited by 371 · see citing works

In vivo quantification of spatially varying mechanical properties in developing tissues

Serwane, F., Mongera, A., Rowghanian, P., Kealhofer, D., Lucio, A. A., Hockenbery, Z. M., & Campàs, O. (2016) · Nature Methods · doi:10.1038/nmeth.4101 · Cited by 368 · see citing works

The use of poly(ethylene glycol) hydrogels to investigate the impact of ECM chemistry and mechanics on smooth muscle cells

Peyton, S. R., Raub, C. B., Keschrumrus, V., & Putnam, A. J. (2006) · Biomaterials · doi:10.1016/j.biomaterials.2006.05.012 · Cited by 357 · see citing works

Two-dimensional mechanical properties of rabbit skin—II. Experimental results

Lanir, Y., & Fung, Y. C. (1974) · Journal of Biomechanics · doi:10.1016/0021-9290(74)90058-x · Cited by 354 · see citing works

Creep and relaxation of nonlinear viscoelastic materials

Saunders, D. W. (1978) · Polymer · doi:10.1016/0032-3861(78)90187-8 · Cited by 340 · see citing works

Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels

Nam, S., Hu, K. H., Butte, M. J., & Chaudhuri, O. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1523906113 · Cited by 336 · see citing works

MR elastography of breast lesions: Understanding the solid/liquid duality can improve the specificity of contrast‐enhanced MR mammography

Sinkus, R., Siegmann, K., Xydeas, T., Tanter, M., Claussen, C. D., & Fink, M. (2007) · Magnetic Resonance in Medicine · doi:10.1002/mrm.21404 · Cited by 332 · see citing works

Cancer cell angiogenic capability is regulated by 3D culture and integrin engagement

Fischbach, C., Kong, H. J., Hsiong, S. X., Evangelista, M. B., Yuen, W. W., & Mooney, D. J. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808932106 · Cited by 312 · see citing works

FRET measurements of cell-traction forces and nano-scale clustering of adhesion ligands varied by substrate stiffness

Kong, H. J., Polte, T. R., Alsberg, E., & Mooney, D. J. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0405873102 · Cited by 308 · see citing works

Strain history dependence of the nonlinear stress response of fibrin and collagen networks

Münster, S., Jawerth, L. M., Leslie, B. A., Weitz, J. I., Fabry, B., & Weitz, D. A. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1222787110 · Cited by 281 · see citing works

Linear viscoelastic behavior of subcutaneous adipose tissue

Geerligs, M., Peters, G. G., Ackermans, P. A. J., Oomens, C. W. J., & Baaijens, F. F. (2008) · Biorheology · doi:10.3233/bir-2008-0517 · Cited by 221 · see citing works

Diffusing Wave Spectroscopy Microrheology of Actin Filament Networks

Palmer, A. F., Mason, T. G., Xu, J., Kuo, S. C., & Wirtz, D. (1999) · Biophysical Journal · doi:10.1016/s0006-3495(99)77271-1 · Cited by 220 · see citing works

Measuring dynamic cell–material interactions and remodeling during 3D human mesenchymal stem cell migration in hydrogels

Schultz, K. M., Kyburz, K. A., & Anseth, K. S. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1511304112 · Cited by 216 · see citing works

Viscoplasticity Enables Mechanical Remodeling of Matrix by Cells

Nam, S., Lee, J. Y., Brownfield, D., & Chaudhuri, O. (2016) · Biophysical Journal · doi:10.1016/j.bpj.2016.10.002 · Cited by 200 · see citing works

Roles of Mechanical Forces and Collagen Failure in the Development of Elastase-induced Emphysema

KONONOV, S., Brewer, K. K., Sakai, H., Cavalcante, F. S. Á., SABAYANAGAM, C. R., Ingenito, E. P., & Suki, B. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.10.2101083 · Cited by 191 · see citing works

On the viscoelastic character of liver tissue: experiments and modelling of the linear behaviour

Liu, Z., & Bilston, L. E. (2000) · Biorheology · doi:10.1177/0006355x2000037003002 · Cited by 188 · see citing works

Passive and active microrheology with optical tweezers

Brau, R. R., Ferrer, J. M., Lee, H., Castro, C. E., Tam, B. K., Tarsa, P. B., Matsudaira, P. T., Boyce, M. C., Kamm, R. D., & Lang, M. J. (2007) · Journal of Optics A Pure and Applied Optics · doi:10.1088/1464-4258/9/8/s01 · Cited by 175 · see citing works

Modulus-driven differentiation of marrow stromal cells in 3D scaffolds that is independent of myosin-based cytoskeletal tension

Parekh, S. H., Chatterjee, K., Lin‐Gibson, S., Moore, N. M., Cicerone, M. T., Young, M. F., & Simon, C. G. (2010) · Biomaterials · doi:10.1016/j.biomaterials.2010.11.065 · Cited by 126 · see citing works

A simple indentation device for measuring micrometer-scale tissue stiffness

Levental, I., Levental, K. R., Klein, E. A., Assoian, R. K., Miller, R. T., Wells, R. G., & Janmey, P. A. (2010) · Journal of Physics Condensed Matter · doi:10.1088/0953-8984/22/19/194120 · Cited by 120 · see citing works

Rheology of fibrin clots. I.

Roberts, W. W., Kramer, O., Rosser, R. W., Nestler, F. H. M., & Ferry, J. D. (1974) · Biophysical Chemistry · doi:10.1016/0301-4622(74)80002-5 · Cited by 118 · see citing works

Gelation of Covalently Cross-Linked PEG−Heparin Hydrogels

Schultz, K. M., Baldwin, A. D., Kiick, K. L., & Furst, E. M. (2009) · Macromolecules · doi:10.1021/ma900766u · Cited by 103 · see citing works

Programming Molecular Association and Viscoelastic Behavior in Protein Networks

Dooling, L. J., Buck, M. E., Zhang, W., & Tirrell, D. A. (2016) · Advanced Materials · doi:10.1002/adma.201506216 · Cited by 103 · see citing works

Cellular Dynamics

Weiss, P. A. (1959) · Reviews of Modern Physics · doi:10.1103/revmodphys.31.11 · Cited by 85 · see citing works

New advances in probing cell–extracellular matrix interactions

Liu, A. P., Chaudhuri, O., & Parekh, S. H. (2017) · Integrative Biology · doi:10.1039/c6ib00251j · Cited by 75 · see citing works

Inelastic behaviour of collagen networks in cell–matrix interactions and mechanosensation

Mohammadi, H., Arora, P. D., Simmons, C. A., Janmey, P. A., & McCulloch, C. A. (2014) · Journal of The Royal Society Interface · doi:10.1098/rsif.2014.1074 · Cited by 65 · see citing works

Mechanical Properties of the Tumor Stromal Microenvironment Probed In Vitro and Ex Vivo by In Situ-Calibrated Optical Trap-Based Active Microrheology

Staunton, J. R., Vieira, W. D., Fung, K. L., Lake, R. G., Devine, A., & Tanner, K. (2016) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-016-0460-9 · Cited by 63 · see citing works

Characterization of hydrogel microstructure using laser tweezers particle tracking and confocal reflection imaging

Kotlarchyk, M. A., Botvinick, E. L., & Putnam, A. J. (2010) · Journal of Physics Condensed Matter · doi:10.1088/0953-8984/22/19/194121 · Cited by 40 · see citing works

Early fracture callus displays smooth muscle‐like viscoelastic properties ex vivo: Implications for fracture healing

McDonald, S. J., Dooley, P. C., McDonald, A. C., Schuijers, J. A., Ward, A. R., & Grills, B. L. (2009) · Journal of Orthopaedic Research® · doi:10.1002/jor.20923 · Cited by 19 · see citing works

Why do phospholipid polymers reduce protein adsorption?

Ishihara, K., Nomura, H., Mihara, T., Kurita, K., Iwasaki, Y., & Nakabayashi, N. (1998) · Journal of Biomedical Materials Research · doi:10.1002/(sici)1097-4636(199802)39:2

Polymeric tissue adhesives

Nam, S., & Mooney, D. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c00798 · Cited by 764 · see citing works

Towards organoid culture without Matrigel

Kozlowski, M. T., Crook, C. J., & Ku, H. T. (2021) · Communications Biology · doi:10.1038/s42003-021-02910-8 · Cited by 409 · see citing works

Structurally Dynamic Hydrogels for Biomedical Applications: Pursuing a Fine Balance between Macroscopic Stability and Microscopic Dynamics

Zhang, K., Feng, Q., Fang, Z., Gu, L., & Bian, L. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00071 · Cited by 397 · see citing works

Carbohydrate-Based Macromolecular Biomaterials

Su, L., Feng, Y., Wei, K., Xu, X., Liu, R., & Chen, G. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.0c01338 · Cited by 336 · see citing works

Varying PEG density to control stress relaxation in alginate-PEG hydrogels for 3D cell culture studies

Nam, S., Stowers, R. S., Lou, J., Xia, Y., & Chaudhuri, O. (2019) · Biomaterials · doi:10.1016/j.biomaterials.2019.02.004 · Cited by 293 · see citing works

Natural Hydrogel-Based Bio-Inks for 3D Bioprinting in Tissue Engineering: A Review

Fatimi, A., Okoro, O. V., Podstawczyk, D., Siminska-Stanny, J., & Shavandi, A. (2022) · Gels · doi:10.3390/gels8030179 · Cited by 276 · see citing works

The Overview of Porous, Bioactive Scaffolds as Instructive Biomaterials for Tissue Regeneration and Their Clinical Translation

Lutzweiler, G., Halili, A. N., & Vrana, N. E. (2020) · Pharmaceutics · doi:10.3390/pharmaceutics12070602 · Cited by 274 · see citing works

Dynamic covalent hydrogels as biomaterials to mimic the viscoelasticity of soft tissues

Tang, S., Richardson, B. M., & Anseth, K. S. (2020) · Progress in Materials Science · doi:10.1016/j.pmatsci.2020.100738 · Cited by 267 · see citing works

Synthetic dynamic hydrogels promote degradation-independent in vitro organogenesis

Chrisnandy, A., Blondel, D., Rezakhani, S., Broguiere, N., & Lutolf, M. P. (2022) · Nature Materials · doi:10.1038/s41563-021-01136-7 · Cited by 237 · see citing works

Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids

Capeling, M. M., Czerwinski, M., Huang, S., Tsai, Y.-H., Wu, A., Nagy, M. S., Juliar, B., Sundaram, N., Song, Y., Han, W. M., et al. (2019) · Stem Cell Reports · doi:10.1016/j.stemcr.2018.12.001 · Cited by 226 · see citing works

A Rapidly Self‐Healing Host–Guest Supramolecular Hydrogel with High Mechanical Strength and Excellent Biocompatibility

Wang, Z., Ren, Y., Zhu, Y., Hao, L., Chen, Y., An, G., Wu, H., Shi, X., & Mao, C. (2018) · Angewandte Chemie International Edition · doi:10.1002/anie.201804400 · Cited by 226 · see citing works

Dynamic Bioinks to Advance Bioprinting

Morgan, F. L. C., Moroni, L., & Baker, M. B. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.201901798 · Cited by 228 · see citing works

3D-printable self-healing and mechanically reinforced hydrogels with host–guest non-covalent interactions integrated into covalently linked networks

Wang, Z., An, G., Zhu, Y., Liu, X., Chen, Y., Wu, H., Wang, Y., Shi, X., & Mao, C. (2019) · Materials Horizons · doi:10.1039/c8mh01208c · Cited by 219 · see citing works

Viscoelastic Cell Microenvironment: Hydrogel‐Based Strategy for Recapitulating Dynamic ECM Mechanics

Ma, Y., Han, T., Yang, Q., Wang, J., Feng, B., Jia, Y., Zhao, W., & Xu, F. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202100848 · Cited by 211 · see citing works

Advanced Bottom‐Up Engineering of Living Architectures

Gaspar, V. M., Lavrador, P., Borges, J., Oliveira, M. B., & Mano, J. F. (2019) · Advanced Materials · doi:10.1002/adma.201903975 · Cited by 204 · see citing works

Boronate Ester Hydrogels for Biomedical Applications: Challenges and Opportunities

Terriac, L., Hélesbeux, J., Maugars, Y., Guicheux, J., Tibbitt, M. W., & Delplace, V. (2024) · Chemistry of Materials · doi:10.1021/acs.chemmater.4c00507 · Cited by 198 · see citing works

Mechanics of 3D Cell–Hydrogel Interactions: Experiments, Models, and Mechanisms

Vernerey, F. J., Sridhar, S. L., Muralidharan, A., & Bryant, S. J. (2021) · Chemical Reviews · doi:10.1021/acs.chemrev.1c00046 · Cited by 183 · see citing works

The extracellular matrix viscoelasticity as a regulator of cell and tissue dynamics

Elosegui-Artola, A. (2021) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2021.04.002 · Cited by 170 · see citing works

Designer biomaterials for mechanobiology

Li, L., Eyckmans, J., & Chen, C. S. (2017) · Nature Materials · doi:10.1038/nmat5049 · Cited by 175 · see citing works

Recent Development of Alginate-Based Materials and Their Versatile Functions in Biomedicine, Flexible Electronics, and Environmental Uses

Teng, K., An, Q., Chen, Y., Zhang, Y., & Zhao, Y. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00116 · Cited by 173 · see citing works

Viscoelasticity in natural tissues and engineered scaffolds for tissue reconstruction

Huang, D., Huang, Y. X., Xiao, Y., Yang, X., Lin, H., Feng, G., Zhu, X., & Zhang, X. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.08.013 · Cited by 169 · see citing works

Designing Hydrogels for 3D Cell Culture Using Dynamic Covalent Crosslinking

Rizwan, M., Baker, A. E. G., & Shoichet, M. S. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202100234 · Cited by 171 · see citing works

Engineering of Hydrogel Materials with Perfusable Microchannels for Building Vascularized Tissues

Xie, R., Zheng, W.-C., Guan, L., Ai, Y., & Liang, Q. (2019) · Small · doi:10.1002/smll.201902838 · Cited by 168 · see citing works

Ideal reversible polymer networks

Parada, G. A., & Zhao, X. (2018) · Soft Matter · doi:10.1039/c8sm00646f · Cited by 164 · see citing works

3D bioprinting of gellan gum and poly (ethylene glycol) diacrylate based hydrogels to produce human-scale constructs with high-fidelity

Wu, D., Yu, Y., Tan, J., Huang, L., Luo, B., Lu, L., & Zhou, C. (2018) · Materials & Design · doi:10.1016/j.matdes.2018.09.040 · Cited by 159 · see citing works

Human lung extracellular matrix hydrogels resemble the stiffness and viscoelasticity of native lung tissue

de Hilster, R. H. J., Sharma, P. K., Jonker, M. R., White, E. S., Gercama, E. A., Roobeek, M., Timens, W., Harmsen, M. C., Hylkema, M. N., & Burgess, J. K. (2020) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00451.2019 · Cited by 155 · see citing works

Synthetic peptide hydrogels as 3D scaffolds for tissue engineering

Ding, X., Zhao, H., Li, Y., Lee, A. L., Li, Z., Fu, M., Li, C., Yang, Y. Y., & Yuan, P. (2020) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2020.10.005 · Cited by 140 · see citing works

Hydrogels and Hydrogel Nanocomposites: Enhancing Healthcare through Human and Environmental Treatment

Gutiérrez, Á. M., Frazar, E. M., Klaus, M. V. X., Paul, P., & Hilt, J. Z. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202101820 · Cited by 139 · see citing works

Engineering multifunctional dynamic hydrogel for biomedical and tissue regenerative applications

Yin, B., Gosecka, M., Bodaghi, M., Crespy, D., Youssef, G., Dodda, J. M., Wong, S. H. D., Imran, A. B., Gosecki, M., Jobdeedamrong, A., et al. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.150403 · Cited by 140 · see citing works

Hydrazone covalent adaptable networks modulate extracellular matrix deposition for cartilage tissue engineering

Richardson, B. M., Wilcox, D. G., Randolph, M. A., & Anseth, K. S. (2018) · Acta Biomaterialia · doi:10.1016/j.actbio.2018.11.014 · Cited by 134 · see citing works

Applications and multidisciplinary perspective on 3D printing techniques: Recent developments and future trends

hadad, A. A. E., Rosa-Sainz, A., Cañete, R., Peralta, E., Begines, B., Balbuena, M., Alcudia, A., & Torres, Y. (2023) · Materials Science and Engineering R Reports · doi:10.1016/j.mser.2023.100760 · Cited by 140 · see citing works

Advances in Gelatin Bioinks to Optimize Bioprinted Cell Functions

Asim, S., Tabish, T. A., Liaqat, U., Ozbolat, I. T., & Rizwan, M. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202203148 · Cited by 135 · see citing works

Assessing cell migration in hydrogels: An overview of relevant materials and methods

Solbu, A. A., Caballero, D., Damigos, S., Kundu, S. C., Reis, R. L., Halaas, Ø., Chahal, A. S., & Strand, B. L. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100537 · Cited by 126 · see citing works

Dynamic matrices with DNA-encoded viscoelasticity for cell and organoid culture

Peng, Y., Hsiao, S., Gupta, K., Ruland, A., Auernhammer, G. K., Maitz, M. F., Boye, S., Lattner, J., Gerri, C., Honigmann, A., et al. (2023) · Nature Nanotechnology · doi:10.1038/s41565-023-01483-3 · Cited by 130 · see citing works

Progress in biomaterials inspired by the extracellular matrix

Chen, Z., Du, C., Liu, S., Liu, J., Yang, Y., Dong, L., Zhao, W., Huang, W., & Lei, Y. (2024) · Giant · doi:10.1016/j.giant.2024.100323 · Cited by 132 · see citing works

Integrating Biomaterials and Food Biopolymers for Cultured Meat Production

Ng, S., & Kurisawa, M. (2020) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.01.017 · Cited by 121 · see citing works

Advancing models of neural development with biomaterials

Roth, J. G., Huang, M. S., Li, T. L., Feig, V. R., Jiang, Y., Cui, B., Greely, H. T., Bao, Z., Pașca, S. P., & Heilshorn, S. C. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00496-y · Cited by 120 · see citing works

Tunable hydrogel viscoelasticity modulates human neural maturation

Roth, J. G., Huang, M. S., Navarro, R. S., Akram, J., LeSavage, B. L., & Heilshorn, S. C. (2023) · Science Advances · doi:10.1126/sciadv.adh8313 · Cited by 121 · see citing works

Viscoelastic Biomaterials for Tissue Regeneration

Wu, D. T. S., Jeffreys, N. C., Diba, M., & Mooney, D. J. (2022) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2022.0040 · Cited by 121 · see citing works

The Plot Thickens: The Emerging Role of Matrix Viscosity in Cell Mechanotransduction

Cantini, M., Donnelly, H., Dalby, M. J., & Salmerón‐Sánchez, M. (2019) · Advanced Healthcare Materials · doi:10.1002/adhm.201901259 · Cited by 116 · see citing works

Recent advances in bio-orthogonal and dynamic crosslinking of biomimetic hydrogels

Arkenberg, M. R., Nguyen, H. D., & Lin, C. (2020) · Journal of Materials Chemistry B · doi:10.1039/d0tb01429j · Cited by 113 · see citing works

Engineering the viscoelasticity of gelatin methacryloyl (GelMA) hydrogels via small “dynamic bridges” to regulate BMSC behaviors for osteochondral regeneration

Liu, C., Yu, Q., Yuan, Z., Guo, Q., Liao, X., Han, F., Feng, T., Liu, G., Zhao, R., Zhu, Z., et al. (2022) · Bioactive Materials · doi:10.1016/j.bioactmat.2022.07.031 · Cited by 109 · see citing works

Hydrogels and Bioprinting in Bone Tissue Engineering: Creating Artificial Stem‐Cell Niches for In Vitro Models

Lewns, F. K., Tsigkou, O., Cox, L. R., Wildman, R. D., Grover, L. M., & Poologasundarampillai, G. (2023) · Advanced Materials · doi:10.1002/adma.202301670 · Cited by 108 · see citing works

Spatiotemporally Controlled Photoresponsive Hydrogels: Design and Predictive Modeling from Processing through Application

Zhu, H., Yang, H., Ma, Y., Lu, T. J., Xu, F., Genin, G. M., & Lin, M. (2020) · Advanced Functional Materials · doi:10.1002/adfm.202000639 · Cited by 106 · see citing works

Soft overcomes the hard: Flexible materials adapt to cell adhesion to promote cell mechanotransduction

Sun, Q., Hou, Y. X., Chu, Z., & Wei, Q. (2021) · Bioactive Materials · doi:10.1016/j.bioactmat.2021.08.026 · Cited by 105 · see citing works

Rational design of hydrogels for immunomodulation

Bu, W., Wu, Y., Ghaemmaghami, A. M., Sun, H., & Mata, Á. (2022) · Regenerative Biomaterials · doi:10.1093/rb/rbac009 · Cited by 106 · see citing works

Extracellular matrix requirements for gastrointestinal organoid cultures

Rezakhani, S., Gjorevski, N., & Lutolf, M. P. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121020 · Cited by 100 · see citing works

Tuning Viscoelasticity in Alginate Hydrogels for 3D Cell Culture Studies

Charbonier, F. W., Indana, D., & Chaudhuri, O. (2021) · Current Protocols · doi:10.1002/cpz1.124 · Cited by 99 · see citing works

Interpenetrating polymer network hydrogels as bioactive scaffolds for tissue engineering

Crosby, C. O., Stern, B., Kalkunte, N., Pedahzur, S., Ramesh, S., & Zoldan, J. (2020) · Reviews in Chemical Engineering · doi:10.1515/revce-2020-0039 · Cited by 86 · see citing works

Diatom Frustule Silica Exhibits Superhydrophilicity and Superhemophilicity

Lee, J., Lee, H. A., Shin, M., Juang, L. J., Kastrup, C. J., Go, G. M., & Lee, H. (2020) · ACS Nano · doi:10.1021/acsnano.0c00621 · Cited by 84 · see citing works

Mechanical reinforcement of granular hydrogels

Charlet, A., Bono, F., & Amstad, E. (2022) · Chemical Science · doi:10.1039/d1sc06231j · Cited by 84 · see citing works

Materials control of the epigenetics underlying cell plasticity

Nemec, S. R., & Kilian, K. A. (2020) · Nature Reviews Materials · doi:10.1038/s41578-020-00238-z · Cited by 83 · see citing works

Injectable liposome-based supramolecular hydrogels for the programmable release of multiple protein drugs

Correa, S., Grosskopf, A. K., Klich, J. H., Hernandez, H. L., & Appel, E. A. (2022) · Matter · doi:10.1016/j.matt.2022.03.001 · Cited by 80 · see citing works

Viscoelasticity Acts as a Marker for Tumor Extracellular Matrix Characteristics

Mierke, C. T. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.785138 · Cited by 77 · see citing works

Traction force microscopy of engineered cardiac tissues

Pasqualini, F. S., Agarwal, A., O’Connor, B. B., Liu, Q., Sheehy, S. P., & Parker, K. K. (2018) · PLoS ONE · doi:10.1371/journal.pone.0194706 · Cited by 77 · see citing works

Force Modulation and Adaptability of 3D‐Bioprinted Biological Actuators Based on Skeletal Muscle Tissue

Mestre, R., Patiño, T., Barceló, X., Anand, S., Perez‐Jiménez, A., & Sánchez, S. (2018) · Advanced Materials Technologies · doi:10.1002/admt.201800631 · Cited by 76 · see citing works

Hydrogels and conductive hydrogels for implantable bioelectronics

Sagdic, K., Lavado, E. F., Mariello, M., Akouissi, O., & Lacour, S. P. (2023) · MRS Bulletin · doi:10.1557/s43577-023-00536-1 · Cited by 76 · see citing works

Cell engineering: Biophysical regulation of the nucleus

Song, Y., Soto, J., Chen, B., Yang, L., & Li, S. (2020) · Biomaterials · doi:10.1016/j.biomaterials.2019.119743 · Cited by 68 · see citing works

Recent Advances in Three-Dimensional Stem Cell Culture Systems and Applications

Wu, X., Su, J., Wei, J., Jiang, N., & Ge, X. (2021) · Stem Cells International · doi:10.1155/2021/9477332 · Cited by 71 · see citing works

Natural Origin Biomaterials for 4D Bioprinting Tissue‐Like Constructs

Costa, P. D. C., Costa, D. C. S., Correia, T. R., Gaspar, V. M., & Mano, J. F. (2021) · Advanced Materials Technologies · doi:10.1002/admt.202100168 · Cited by 68 · see citing works

Digital light processing-based 3D bioprinting of κ-carrageenan hydrogels for engineering cell-loaded tissue scaffolds

Kumari, S., Mondal, P., & Chatterjee, K. (2022) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2022.119508 · Cited by 69 · see citing works

Stress-relaxing double-network hydrogel for chondrogenic differentiation of stem cells

Li, W., Wu, D., Hu, D., Zhu, S., Pan, C., Jiao, Y., Li, L., Luo, B., Zhou, C., & Lu, L. (2019) · Materials Science and Engineering C · doi:10.1016/j.msec.2019.110333 · Cited by 69 · see citing works

Oxime Cross-Linked Alginate Hydrogels with Tunable Stress Relaxation

Sánchez-Morán, H., Ahmadi, A., Vogler, B., & Roh, K. (2019) · Biomacromolecules · doi:10.1021/acs.biomac.9b01100 · Cited by 68 · see citing works

Progress in the mechanical modulation of cell functions in tissue engineering

Dey, K., Roca, E., Ramorino, G., & Sartore, L. (2020) · Biomaterials Science · doi:10.1039/d0bm01255f · Cited by 64 · see citing works

Dynamic Hydrogels with Viscoelasticity and Tunable Stiffness for the Regulation of Cell Behavior and Fate

Zhang, Y., Wang, Z., Sun, Q., Li, Q., Li, S., & Li, X. (2023) · Materials · doi:10.3390/ma16145161 · Cited by 65 · see citing works

Biomaterials to enhance adoptive cell therapy

Eckman, N., Nejatfard, A., Cavet, R., Grosskopf, A. K., & Appel, E. A. (2024) · Nature Reviews Bioengineering · doi:10.1038/s44222-023-00148-z · Cited by 65 · see citing works

Consideration of the Mechanical Properties of Hydrogels for Brain Tissue Engineering and Brain-on-a-chip

Kim, H. N., & Choi, N. (2019) · BioChip Journal · doi:10.1007/s13206-018-3101-7 · Cited by 65 · see citing works

Polyacrylamide Hydrogels as Versatile Biomimetic Platforms to Study Cell‐Materials Interactions

Miloš, F., & del Campo, A. (2024) · Advanced Materials Interfaces · doi:10.1002/admi.202400404 · Cited by 67 · see citing works

Biomechanical factors in three-dimensional tissue bioprinting

Ning, L., Gil, C. J., Hwang, B., Theus, A. S., Perez, L., Tomov, M. L., Bauser‐Heaton, H. D., & Serpooshan, V. (2020) · Applied Physics Reviews · doi:10.1063/5.0023206 · Cited by 62 · see citing works

Mass Spectrometry-Based Atlas of Extracellular Matrix Proteins across 25 Mouse Organs

McCabe, M. C., Saviola, A. J., & Hansen, K. C. (2023) · Journal of Proteome Research · doi:10.1021/acs.jproteome.2c00526 · Cited by 62 · see citing works

Tissue engineering the cancer microenvironment—challenges and opportunities

Papalazarou, V., Salmerón‐Sánchez, M., & Machesky, L. M. (2018) · Biophysical Reviews · doi:10.1007/s12551-018-0466-8 · Cited by 61 · see citing works

Lose the Stress: Viscoelastic Materials for Cell Engineering

Carvalho, E. M., & Kumar, S. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2022.03.058 · Cited by 60 · see citing works

Recapitulating hypoxic metabolism in cartilaginous organoids via adaptive cell-matrix interactions enhances histone lactylation and cartilage regeneration

Yang, B., Li, Z., Yang, Z., Zhao, P., Lin, S., Wu, J., Liu, W., Yang, X., Xie, X., Zong, Z., et al. (2025) · Nature Communications · doi:10.1038/s41467-025-57779-6 · Cited by 58 · see citing works

Brain-on-a-Chip: Characterizing the next generation of advanced in vitro platforms for modeling the central nervous system

Maoz, B. M. (2021) · APL Bioengineering · doi:10.1063/5.0055812 · Cited by 57 · see citing works

Schiff base crosslinked hyaluronic acid hydrogels with tunable and cell instructive time-dependent mechanical properties

Kohlan, T. B., Wen, Y., Mini, C., & Finne‐Wistrand, A. (2024) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2024.122173 · Cited by 57 · see citing works

Colloidal hydrogels made of gelatin nanoparticles exhibit fast stress relaxation at strains relevant for cell activity

Bertsch, P., Andrée, L., Besheli, N. H., & Leeuwenburgh, S. C. G. (2021) · Acta Biomaterialia · doi:10.1016/j.actbio.2021.10.053 · Cited by 56 · see citing works

Recent advances in 3D hydrogel culture systems for mesenchymal stem cell-based therapy and cell behavior regulation

Hu, X., Xia, Z., & Cai, K. (2022) · Journal of Materials Chemistry B · doi:10.1039/d1tb02537f · Cited by 57 · see citing works

Tailoring supramolecular guest–host hydrogel viscoelasticity with covalent fibrinogen double networks

Loebel, C., Ayoub, A., Galarraga, J. H., Kossover, O., Yameen, H. S., Seliktar, D., & Burdick, J. A. (2019) · Journal of Materials Chemistry B · doi:10.1039/c8tb02593b · Cited by 56 · see citing works

Hydrogel Mechanics Influence the Growth and Development of Embedded Brain Organoids

Cassel de Camps, C., Aslani, S., Stylianesis, N., Nami, H., Mohamed, N.-V., Durcan, T. M., & Moraes, C. (2022) · ACS Applied Bio Materials · doi:10.1021/acsabm.1c01047 · Cited by 55 · see citing works

Mechanochemical Patternable ECM‐Mimetic Hydrogels for Programmed Cell Orientation

Lavrador, P., Gaspar, V. M., & Mano, J. F. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.201901860 · Cited by 55 · see citing works

Electrical Programming of Soft Matter: Using Temporally Varying Electrical Inputs To Spatially Control Self Assembly

Yan, K., Liu, Y., Zhang, J., Correa, S. O., Shang, W., Tsai, C., Bentley, W. E., Shen, J., Scarcelli, G., Raub, C. B., et al. (2017) · Biomacromolecules · doi:10.1021/acs.biomac.7b01464 · Cited by 54 · see citing works

Dynamic freedom: substrate stress relaxation stimulates cell responses

Dey, K., Agnelli, S., & Sartore, L. (2018) · Biomaterials Science · doi:10.1039/c8bm01305e · Cited by 54 · see citing works

Catechol-Functionalized Elastin-like Polypeptides as Tissue Adhesives

Desai, M. S., Chen, M., Hong, F. H. J., Lee, J. H., Wu, Y., & Lee, S. (2020) · Biomacromolecules · doi:10.1021/acs.biomac.0c00740 · Cited by 54 · see citing works

Autonomous self-healing hydrogel with anti-drying properties and applications in soft robotics

Naranjo, A., Martín, C., López‐Díaz, A., Martín‐Pacheco, A., Rodríguez, A. M., Patiño, F. J., Herrero, M. A., Vázquez, A. S., & Vázquez, E. (2020) · Applied Materials Today · doi:10.1016/j.apmt.2020.100806 · Cited by 53 · see citing works

Translational mechanobiology: Designing synthetic hydrogel matrices for improved in vitro models and cell-based therapies

Huebsch, N. (2019) · Acta Biomaterialia · doi:10.1016/j.actbio.2019.05.055 · Cited by 52 · see citing works

Cell‐Instructive Multiphasic Gel‐in‐Gel Materials

Kühn, S., Sievers, J., Stoppa, A., Träber, N., Zimmermann, R., Welzel, P. B., & Werner, C. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201908857 · Cited by 53 · see citing works

Covalent cross-linking of basement membrane-like matrices physically restricts invasive protrusions in breast cancer cells

Wisdom, K. M., Indana, D., Chou, P.-E., Desai, R. M., Kim, T., & Chaudhuri, O. (2019) · Matrix Biology · doi:10.1016/j.matbio.2019.05.006 · Cited by 51 · see citing works

Solution viscosity regulates chondrocyte proliferation and phenotype during 3D culture

Lee, K., Chen, Y., Li, X., Wang, Y.-T., Kawazoe, N., Yang, Y., & Chen, G. (2019) · Journal of Materials Chemistry B · doi:10.1039/c9tb02204j · Cited by 50 · see citing works

Mechanical Characterization for Cellular Mechanobiology: Current Trends and Future Prospects

Narasimhan, B. N., Ting, M. S., Kollmetz, T., Horrocks, M. S., Chalard, A. E., & Malmström, J. (2020) · Frontiers in Bioengineering and Biotechnology · doi:10.3389/fbioe.2020.595978 · Cited by 50 · see citing works

Electrophysiology Read-Out Tools for Brain-on-Chip Biotechnology

Forró, C., Caron, D., Angotzi, G. N., Gallo, V., Berdondini, L., Santoro, F., Palazzolo, G., & Panuccio, G. (2021) · Micromachines · doi:10.3390/mi12020124 · Cited by 50 · see citing works

Mind the Viscous Modulus: The Mechanotransductive Response to the Viscous Nature of Isoelastic Matrices Regulates Stem Cell Chondrogenesis

Walker, M., Pringle, E. W., Ciccone, G., Oliver‐Cervelló, L., Tassieri, M., Gourdon, D., & Cantini, M. (2023) · Advanced Healthcare Materials · doi:10.1002/adhm.202302571 · Cited by 48 · see citing works

Pillar[5]arene-Based Resilient Supramolecular Gel with Dual-Stimuli Responses and Self-Healing Properties

Chen, J.-F., & Chen, P. (2019) · ACS Applied Polymer Materials · doi:10.1021/acsapm.9b00516 · Cited by 47 · see citing works

Viscoelastic properties of microgel thin films control fibroblast modes of migration and pro-fibrotic responses

Chester, D., Kathard, R., Nortey, J. N., Nellenbach, K. A., & Brown, A. C. (2018) · Biomaterials · doi:10.1016/j.biomaterials.2018.09.012 · Cited by 46 · see citing works

Phototunable Viscoelasticity in Hydrogels Through Thioester Exchange

Carberry, B. J., Rao, V. V., & Anseth, K. S. (2020) · Annals of Biomedical Engineering · doi:10.1007/s10439-020-02460-w · Cited by 45 · see citing works

Characterizing and Engineering Biomimetic Materials for Viscoelastic Mechanotransduction Studies

Cacopardo, L., Guazzelli, N., & Ahluwalia, A. (2021) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2021.0151 · Cited by 45 · see citing works

Facile strategy involving low-temperature chemical cross-linking to enhance the physical and biological properties of hyaluronic acid hydrogel

Baek, J., Fan, Y., Jeong, S., Lee, H.-Y., Jung, H., Kim, H., Kim, S., & Jang, T. (2018) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2018.09.014 · Cited by 44 · see citing works

Magneto-diffusion-viscohyperelasticity for magneto-active hydrogels: Rate dependences across time scales

Garcia‐Gonzalez, D., & Landis, C. M. (2020) · Journal of the Mechanics and Physics of Solids · doi:10.1016/j.jmps.2020.103934 · Cited by 43 · see citing works

Hydrogels to engineer tumor microenvironments in vitro

Fernando, K., Kwang, L. G., Lim, J. T. C., & Fong, E. L. S. (2021) · Biomaterials Science · doi:10.1039/d0bm01943g · Cited by 43 · see citing works

Hydrogel Coatings of Implants for Pathological Bone Repair

Li, M., Fan, Y., Ran, M., Chen, H., Han, J., Zhai, J., Wang, Z., Ning, C., Shi, Z., & Yu, P. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202401296 · Cited by 43 · see citing works

Chitosan-based high-strength supramolecular hydrogels for 3D bioprinting

Xu, J., Zhang, M., Du, W., Zhao, J., Ling, G., & Zhang, P. (2022) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2022.07.206 · Cited by 43 · see citing works

Viscoelastic Cell Microenvironment: Hydrogel‐Based Strategy for Recapitulating Dynamic ECM Mechanics

Ma, Y., Han, T., Yang, Q., Wang, J., Feng, B., Jia, Y., Zhao, W., & Xu, F. (2021) · Advanced Functional Materials · doi:10.1002/adfm.202100848 · Cited by 211 · see citing works

Hydrogels mimicking the viscoelasticity of extracellular matrix for regenerative medicine: Design, application, and molecular mechanism

Li, L., Wang, S., Chen, Y., Dong, S., Zhang, C., Liao, L., & Zhang, W. (2024) · Chemical Engineering Journal · doi:10.1016/j.cej.2024.155206 · Cited by 37 · see citing works

Dynamic Hydrogels with Viscoelasticity and Tunable Stiffness for the Regulation of Cell Behavior and Fate

Zhang, Y., Wang, Z., Sun, Q., Li, Q., Li, S., & Li, X. (2023) · Materials · doi:10.3390/ma16145161 · Cited by 65 · see citing works

Effects of extracellular matrix viscoelasticity on cellular behaviour

Chaudhuri, O., Cooper-White, J., Janmey, P. A., Mooney, D. J., & Shenoy, V. B. (2020) · Nature · doi:10.1038/s41586-020-2612-2 · Cited by 2,224 · see citing works

Stress relaxing hyaluronic acid-collagen hydrogels promote cell spreading, fiber remodeling, and focal adhesion formation in 3D cell culture

Lou, J., Stowers, R. S., Nam, S., Xia, Y., & Chaudhuri, O. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.11.004 · Cited by 524 · see citing works