The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Type 2C protein phosphatases directly regulate abscisic acid-activated protein kinases in Arabidopsis
Open accessAbstract
Abscisic acid (ABA) signaling is important for stress responses and developmental processes in plants. A subgroup of protein phosphatase 2C (group A PP2C) or SNF1-related protein kinase 2 (subclass III SnRK2) have been known as major negative or positive regulators of ABA signaling, respectively. Here, we demonstrate the physical and functional linkage between these two major signaling factors. Group A PP2Cs interacted physically with SnRK2s in various combinations, and efficiently inactivated ABA-activated SnRK2s via dephosphorylation of multiple Ser/Thr residues in the activation loop. This step was suppressed by the RCAR/PYR ABA receptors in response to ABA. However the abi1–1 mutated PP2C did not respond to the receptors and constitutively inactivated SnRK2. Our results demonstrate that group A PP2Cs act as ‘gatekeepers’ of subclass III SnRK2s, unraveling an important regulatory mechanism of ABA signaling.
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Cites
Arabidopsis mesophyll protoplasts: a versatile cell system for transient gene expression analysis
Yoo, S.-D., Cho, Y.-H., & Sheen, J. (2007) · Nature Protocols · doi:10.1038/nprot.2007.199 · Cited by 5,083
Abscisic Acid Inhibits Type 2C Protein Phosphatases via the PYR/PYL Family of START Proteins
Park, S.-Y., Fung, P., Nishimura, N., Jensen, D. R., Fujii, H., Zhao, Y., Lumba, S., Santiago, J., Rodrigues, A., Chow, T.-F. F., et al. (2009) · Science · doi:10.1126/science.1173041 · Cited by 2,974
Yamaguchi-Shinozaki, K., & Shinozaki, K. (2006) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105444 · Cited by 2,950
Self-citationRegulators of PP2C Phosphatase Activity Function as Abscisic Acid Sensors
Ma, Y., Szostkiewicz, I., Korte, A., Moes, D., Yang, Y., Christmann, A., & Grill, E. (2009) · Science · doi:10.1126/science.1172408 · Cited by 2,459
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Rensing, S. A., Lang, D., Zimmer, A. D., Terry, A., Salamov, A., Shapiro, H., Nishiyama, T., Perroud, P.-F., Lindquist, E. A., Kamisugi, Y., et al. (2008) · Science · doi:10.1126/science.1150646 · Cited by 1,852
Walter, M., Chaban, C., Schütze, K., Batistic, O., Weckermann, K., Näke, C., Blazevic, D., Grefen, C., Schumacher, K., Oecking, C., et al. (2004) · The Plant Journal · doi:10.1111/j.1365-313x.2004.02219.x · Cited by 1,728
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Hellens, R. P., Edwards, E. A., Leyland, N. R., Bean, S., & Mullineaux, P. M. (2000) · Plant Molecular Biology · doi:10.1023/a:1006496308160 · Cited by 1,562
THE AMP-ACTIVATED/SNF1 PROTEIN KINASE SUBFAMILY: Metabolic Sensors of the Eukaryotic Cell?
Hardie, D. G., Carling, D., & Carlson, M. (1998) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.67.1.821 · Cited by 1,435
Molecular Aspects of Seed Dormancy
Finkelstein, R., Reeves, W., Ariizumi, T., & Steber, C. (2008) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.59.032607.092740 · Cited by 1,379
Mustilli, A.-C., Merlot, S., Vavasseur, A., Fenzi, F., & Giraudat, J. (2002) · The Plant Cell · doi:10.1105/tpc.007906 · Cited by 1,231
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Hsu, P., Dubeaux, G., Takahashi, Y., & Schroeder, J. I. (2021) · The Plant Journal · doi:10.1111/tpj.15067 · Cited by 546
MicroRNA156 improves drought stress tolerance in alfalfa ( Medicago sativa ) by silencing SPL13
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Metadata
- Authors
- Umezawa, T., Sugiyama, N., Mizoguchi, M., Hayashi, S., Myouga, F., Yamaguchi-Shinozaki, K., Ishihama, Y., Hirayama, T., & Shinozaki, K.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2009-10-13
- Volume
- 106
- Issue
- 41
- Pages
- 17588-17593
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2106396116
- Cited by
- 1,123
- References
- 34
- FWCI
- 55.92
- Type
- journal article
- Language
- en
- Open access
- green
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- Umezawa, T., Sugiyama, N., Mizoguchi, M., Hayashi, S., Myouga, F., Yamaguchi-Shinozaki, K., Ishihama, Y., Hirayama, T., & Shinozaki, K. (2009). Type 2C protein phosphatases directly regulate abscisic acid-activated protein kinases in Arabidopsis. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.0907095106
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