The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
Synchronous and Stochastic Patterns of Gene Activation in the Drosophila Embryo
Open accessAbstract
Stalled Development?: Most developmental control genes that pattern the Drosophila embryo appear to have stalled RNA polymerase II (Pol II) bound to them prior to their activation. Classical studies on the Drosophila heat shock genes have shown that stalled Pol II renders these genes “poised” for rapid induction by stress. Boettiger and Levine (p. 471 ) now provide evidence for another potential function of stalled Pol II: Stalled genes exhibit synchronous patterns of gene activation in the early Drosophila embryo so that most or all cells in an embryonic tissue display nascent transcripts at the onset of expression. This synchrony might promote transcriptional precision during development.
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Cites
Stochastic mRNA Synthesis in Mammalian Cells
Raj, A., Peskin, C. S., Tranchina, D., Vargas, D. Y., & Tyagi, S. (2006) · PLoS Biology · doi:10.1371/journal.pbio.0040309 · Cited by 1,737
Control of Stochasticity in Eukaryotic Gene Expression
Raser, J. M., & O'Shea, E. K. (2004) · Science · doi:10.1126/science.1098641 · Cited by 1,425
Shadow enhancers as a source of evolutionary novelty
Hong, J.-W., Hendrix, D. A., & Levine, M. S. (2008) · Science · doi:10.1126/science.1160631 · Cited by 474
Self-citationFrancois, V, Solloway, M., O'Neill, J. W., Emery, J., & Bier, E. (1994) · Genes & Development · doi:10.1101/gad.8.21.2602 · Cited by 308
González-Crespo, S., & Levine, M. (1993) · Genes & Development · doi:10.1101/gad.7.9.1703 · Cited by 79
Self-citationAn anteroposterior Dorsal gradient in the Drosophila embryo
Huang, A. M., Rusch, J., & Levine, M. (1997) · Genes & Development · doi:10.1101/gad.11.15.1963 · Cited by 59
Self-citation
Cited by
Mammalian genes are transcribed with widely different bursting kinetics
Suter, D. M., Molina, N., Gatfield, D., Schneider, K., Schibler, U., & Naef, F. (2011) · Science · doi:10.1126/science.1198817 · Cited by 927
Eukaryotic core promoters and the functional basis of transcription initiation
Haberle, V., & Stark, A. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0028-8 · Cited by 774
Defining mechanisms that regulate RNA polymerase II transcription in vivo
Fuda, N. J., Ardehali, M. B., & Lis, J. T. (2009) · Nature · doi:10.1038/nature08449 · Cited by 576
Phenotypic robustness conferred by apparently redundant transcriptional enhancers
Frankel, N., Davis, G. K., Vargas, D., Wang, S., Payre, F., & Stern, D. L. (2010) · Nature · doi:10.1038/nature09158 · Cited by 510
Hah, N., Danko, C. G., Core, L., Waterfall, J. J., Siepel, A., Lis, J. T., & Kraus, W. L. (2011) · Cell · doi:10.1016/j.cell.2011.03.042 · Cited by 490
Metadata
- Authors
- Boettiger, A. N., & Levine, M.
- Venue
- Science
- Published
- 2009-07-24
- Volume
- 325
- Issue
- 5939
- Pages
- 471-473
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2043562679
- Cited by
- 257
- References
- 6
- FWCI
- 9.72
- Type
- journal article
- Language
- en
- Open access
- green
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