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Cited by 965

The DOI matches its Crossref record; 57 of the 57 references it cites were found in a registry or an index.

The Genetic Basis for Bacterial Mercury Methylation

Parks, Jerry M., Johs, Alexander, Podar, Mircea, Bridou, Romain, Hurt, Richard A., Smith, Steven D., Tomanicek, Stephen J., Qian, Yun, Brown, Steven D., Brandt, Craig C., Palumbo, Anthony V., Smith, Jeremy C., Wall, Judy D., Elias, Dwayne A., Liang, Liyuan·2013·Science

Abstract

Mercury Methylating Microbes: Mercury (Hg) most commonly becomes bioavailable and enters the food web as the organic form methylmercury, where it induces acute toxicity effects that can be magnified up the food chain. But most natural and anthropogenic Hg exists as inorganic Hg 2+ and is only transformed into methylmercury by anaerobic microorganisms—typically sulfur-reducing bacteria. Using comparative genomics, Parks et al. (p. 1332 , published online 7 February; see the Perspective by Poulain and Barkay ) identified two genes that encode a corrinoid and iron-sulfur proteins in six known Hg-methylating bacteria but were absent in nonmethylating bacteria. In two distantly related model Hg-methylating bacteria, deletion of either gene—or both genes simultaneously—reduced the ability for the bacteria to produce methylmercury but did not impair cellular growth. The presence of this two-gene cluster in several other bacterial and lineages for which genome sequences are available suggests the ability to produce methylmercury may be more broadly distributed in the microbial world than previously recognized.

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Metadata

Authors
Parks, J. M., Johs, A., Podar, M., Bridou, R., Hurt, R. A., Smith, S. D., Tomanicek, S. J., Qian, Y., Brown, S. D., Brandt, C. C., Palumbo, A. V., Smith, J. C., Wall, J. D., Elias, D. A., & Liang, L.
Venue
Science
Published
2013-03-15
Volume
339
Issue
6125
Pages
1332-1335
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2004999616
Cited by
965
References
57
FWCI
47.42
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: The Genetic Basis for Bacterial Mercury Methylation. https://app.cochat.ai/papers/10.1126/science.1230667
The paper
Parks, J. M., Johs, A., Podar, M., Bridou, R., Hurt, R. A., Smith, S. D., Tomanicek, S. J., Qian, Y., Brown, S. D., Brandt, C. C., Palumbo, A. V., Smith, J. C., Wall, J. D., Elias, D. A., & Liang, L. (2013). The Genetic Basis for Bacterial Mercury Methylation. Science. https://doi.org/10.1126/science.1230667

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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