The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet?
Open accessAbstract
A Shift in Cancer's Inflammatory Balance: One of the many factors that contribute to the initiation and progression of cancer is inflammation. Inflammation can support tumor development, both directly and indirectly, and tumors can promote a chronic inflammatory environment that results in immunosuppression, which benefits the tumor. Coussens et al. (p. 286 ) review the components of the immune system that contribute to the chronic inflammation seen in tumors. Potential therapies might shift this inflammatory environment toward one more characteristic of an acute, resolving inflammation, similar to what is observed during a pathogenic infection. Such a shift would relieve immunosuppression and drive antitumor immunity that, when combined with other therapies, may ultimately result in tumor cell clearance.
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Cites
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Cited by
Robust enumeration of cell subsets from tissue expression profiles
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Tumor-Associated Macrophages: From Mechanisms to Therapy
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“Several recent studies suggest that such an approach is feasible and therapeutic (Coussens et al., 2013; De Palma and Lewis, 2013).”
BackgroundInfluentialThe immune contexture in cancer prognosis and treatment
Fridman, W. H., Zitvogel, L., Sautès–Fridman, C., & Kroemer, G. (2017) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2017.101 · Cited by 2,263
Self-citationDiversity, Mechanisms, and Significance of Macrophage Plasticity
Locati, M., Curtale, G., & Mantovani, A. (2020) · Annual Review of Pathology: Mechanisms of Disease · doi:10.1146/annurev-pathmechdis-012418-012718 · Cited by 2,199
Metadata
- Authors
- Coussens, L. M., Zitvogel, L., & Palucka, A. K.
- Venue
- Science
- Published
- 2013-01-18
- Volume
- 339
- Issue
- 6117
- Pages
- 286-291
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2101327682
- Cited by
- 1,079
- References
- 73
- FWCI
- 58.21
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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