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Networks of bZIP Protein-Protein Interactions Diversified Over a Billion Years of Evolution
Open accessAbstract
bZIPping Through Evolution: The basic region-leucine zipper (bZIP) transcription factors are found in many species and can form complexes that bind to DNA and affect transcription. Reinke et al. (p. 730 ) analyzed interactions for over 3000 bZIPs within and among five metazoan and two unicellular species. The results reveal differences within bZIP interactive networks that have accumulated over time and identify plasticity among interactions and changes in binding specificity that relate to specific amino acid residue changes.
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Metadata
- Authors
- Reinke, A. W., Baek, J., Ashenberg, O., & Keating, A. E.
- Venue
- Science
- Published
- 2013-05-10
- Volume
- 340
- Issue
- 6133
- Pages
- 730-734
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1965021143
- Cited by
- 206
- References
- 2
- FWCI
- 6.05
- Type
- journal article
- Language
- en
- Open access
- green
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