The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Conserved Regulation of Cardiac Calcium Uptake by Peptides Encoded in Small Open Reading Frames
Open accessAbstract
smORFing for Calcium: Genomes contain thousands of small open reading frames (smORFs), short DNA sequences coding for peptides of less than 100 amino acids. Magny et al. (p. 1116 , published on 22 August) describe two smORF-encoded peptides of less than 30 amino acids regulating calcium transport and, hence, regular heart contraction, in the fruit fly Drosophila . These peptides seem to have been conserved for more than 550 million years in a range of species from flies to humans, where they have been implicated in severe heart diseases. Such conservation suggests that smORFs might be an ancient part of our functional genome.
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Pervasive functional translation of noncanonical human open reading frames
Chen, J., Brunner, A.-D., Cogan, J. Z., Nuñez, J. K., Fields, A. P., Adamson, B., Itzhak, D. N., Li, J. Y., Mann, M., Leonetti, M. D., et al. (2020) · Science · doi:10.1126/science.aay0262 · Cited by 655
Metadata
- Authors
- Magny, E. G., Pueyo, J. I., Pearl, F. M. G., Cespedes, M. A., Niven, J. E., Bishop, S. A., & Couso, J. P.
- Venue
- Science
- Published
- 2013-09-06
- Volume
- 341
- Issue
- 6150
- Pages
- 1116-1120
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1970569349
- Cited by
- 366
- References
- 27
- FWCI
- 18.64
- Type
- journal article
- Language
- en
- Open access
- green
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- Magny, E. G., Pueyo, J. I., Pearl, F. M. G., Cespedes, M. A., Niven, J. E., Bishop, S. A., & Couso, J. P. (2013). Conserved Regulation of Cardiac Calcium Uptake by Peptides Encoded in Small Open Reading Frames. Science. https://doi.org/10.1126/science.1238802
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