The DOI matches its Crossref record.
Diabetes Mellitus: Induction in Mice by Encephalomyocarditis Virus
Abstract
Hyperglycemia and lesions of the pancreatic islets of Langerhans developed in some, but not all, adult mice infected with a variant of the encephalomyocarditis virus. Large amounts of virus were recovered from the pancreas during acute stages of infection. At this time blood glucose concentrations were markedly elevated and the islets of Langerhans exhibited focal necrosis and degranulation of beta cells. Evidence of abnormal glucose metabolism persisted for varying periods after recovery from the infection. The islets of Langerhans of chronically hyperglycemic mice were distorted and decreased in size, and the beta cells were degranulated. Encephalomyocarditis virus appears to cause diabetes mellitus by reducing the mass of functional beta cells of the islets of Langerhans.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
The use of animal models in diabetes research
King, A. J. (2012) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2012.01911.x · Cited by 1,303
Type 1 Diabetes: Etiology, Immunology, and Therapeutic Strategies
Van Belle, T. L., Coppieters, K. T., & Von Herrath, M. G. (2011) · Physiological Reviews · doi:10.1152/physrev.00003.2010 · Cited by 1,022
RUBELLA INFECTION AND DIABETES MELLITUS
Menser, M., Forrest, J., & Bransby, R. (1978) · The Lancet · doi:10.1016/s0140-6736(78)90001-6 · Cited by 351
The Discovery of Type 1 Diabetes
Gale, E. A. M. (2001) · Diabetes · doi:10.2337/diabetes.50.2.217 · Cited by 157
HL-A ANTIGENS AND DIABETES MELLITUS
Cudworth, A. G., & Woodrow, J. C. (1974) · The Lancet · doi:10.1016/s0140-6736(74)90930-1 · Cited by 141
Metadata
- Authors
- Craighead, J. E., & McLane, M. F.
- Venue
- Science
- Published
- 1968-11-22
- Volume
- 162
- Issue
- 3856
- Pages
- 913-914
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2004228512
- Cited by
- 298
- References
- 0
- FWCI
- 5.39
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Diabetes Mellitus: Induction in Mice by Encephalomyocarditis Virus. https://app.cochat.ai/papers/10.1126/science.162.3856.913
- The paper
- Craighead, J. E., & McLane, M. F. (1968). Diabetes Mellitus: Induction in Mice by Encephalomyocarditis Virus. Science. https://doi.org/10.1126/science.162.3856.913
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
