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Cited by 979

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus

Like, Arthur A., Rossini, Aldo A.·1976·Science
DOI 10.1126/science.180605
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Abstract

Multiple small injections of streptozotocin in mice produce pancreatic insulitis, with progression to nearly complete beta cell destruction and diabetes mellitus. The timing and appearance of the inflammatory islet lesions suggest but do not prove that streptozotocin acts by initiating a cell-mediated immune reaction. Ultrastructural evidence of abundant type C viruses within beta cells of treated mice suggests that streptozotocin may activate murine leukemia virus in vivo in susceptible hosts.

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Crossref · 10.1126/science.180605

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Metadata

Authors
Like, A. A., & Rossini, A. A.
Venue
Science
Publisher
American Association for the Advancement of Science (AAAS)
Published
1976-07-30
Volume
193
Issue
4251
Pages
415-417
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
DOI
10.1126/science.180605
OpenAlex
W2010357177
Cited by
979
References
1
FWCI
7.58
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus. https://app.cochat.ai/papers/10.1126/science.180605
The paper
Like, A. A., & Rossini, A. A. (1976). Streptozotocin-Induced Pancreatic Insulitis: New Model of Diabetes Mellitus. Science. https://doi.org/10.1126/science.180605

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.