The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity
Abstract
The role of major histocompatibility complex (MHC) class I expression in natural killer (NK) cell target recognition is controversial. Normal T cell blasts from MHC class I-deficient mutant mice were found to serve as target cells for NK cells in vitro, which suggests that MHC class I molecules are directly involved in NK cell recognition. Spleen cells from the mutant mice were deficient in their ability to lyse MHC class I-deficient target cells or NK-susceptible tumor targets, and mutant mice could not reject allogeneic bone marrow. Thus, class I molecules may participate in the positive selection or tolerance induction of NK cells.
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Cites
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Cited by
Innate or adaptive immunity? The example of natural killer cells
Vivier, E., Raulet, D. H., Moretta, A., Caligiuri, M. A., Zitvogel, L., Lanier, L. L., Yokoyama, W. M., & Ugolini, S. (2011) · Science · doi:10.1126/science.1198687 · Cited by 2,824
Self-citationRoles of the immune system in cancer: From tumor initiation to metastatic progression
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Rae1 and H60 ligands of the NKG2D receptor stimulate tumour immunity
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Self-citationHLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells
Gornalusse, G. G., Hirata, R. K., Funk, S. E., Riolobos, L., Lopes, V. S., Manske, G., Prunkard, D., Colunga, A. G., Hanafi, L.-A., Clegg, D. O., et al. (2017) · Nature Biotechnology · doi:10.1038/nbt.3860 · Cited by 639
Metadata
- Authors
- Liao, N.-S., Bix, M., Zijlstra, M., Jaenisch, R., & Raulet, D.
- Venue
- Science
- Published
- 1991-07-12
- Volume
- 253
- Issue
- 5016
- Pages
- 199-202
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2054726996
- Cited by
- 490
- References
- 25
- FWCI
- 9.01
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity. https://app.cochat.ai/papers/10.1126/science.1853205
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- Liao, N.-S., Bix, M., Zijlstra, M., Jaenisch, R., & Raulet, D. (1991). MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK Activity. Science. https://doi.org/10.1126/science.1853205
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
