The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Ca 2+ -Induced Ca 2+ Release in Sea Urchin Egg Homogenates: Modulation by Cyclic ADP-Ribose
Abstract
Calcium-induced calcium release (CICR) may function widely in calcium-mediated cell signaling, but has been most thoroughly characterized in muscle cells. In a homogenate of sea urchin eggs, which display transients in the intracellular free calcium concentration ([Ca 2+ ] i ) during fertilization and anaphase, addition of Ca 2+ triggered CICR. Ca 2+ release was also induced by the CICR modulators ryanodine and caffeine. Responses to both Ca 2+ and CICR modulators (but not Ca 2+ release mediated by inositol 1,4,5-trisphosphate) were inhibited by procaine and ruthenium red, inhibitors of CICR. Intact eggs also displayed transients of [Ca 2+ ] i when microinjected with ryanodine. Cyclic ADP-ribose, a metabolite with potent Ca 2+ -releasing properties, appears to act by way of the CICR mechanism and may thus be an endogenous modulator of CICR. A CICR mechanism is present in these nonmuscle cells as is assumed in various models of intracellular Ca 2+ wave propagation.
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Cites
Glutamate Induces Calcium Waves in Cultured Astrocytes: Long-Range Glial Signaling
Cornell-Bell, A. H., Finkbeiner, S. M., Cooper, M. S., & Smith, S. J. (1990) · Science · doi:10.1126/science.1967852 · Cited by 1,846
Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor
Takeshima, H., Nishimura, S., Matsumoto, T., Ishida, H., Kangawa, K., Minamino, N., Matsuo, H., Ueda, M., Hanaoka, M., Hirose, T., et al. (1989) · Nature · doi:10.1038/339439a0 · Cited by 1,146
Cited by
Inositol trisphosphate and calcium signalling
Berridge, M. J. (1993) · Nature · doi:10.1038/361315a0 · Cited by 6,545
Partida-Sánchez, S., Cockayne, D. A., Monard, S., Jacobson, E. L., Oppenheimer, N., Garvy, B., Kusser, K., Goodrich, S., Howard, M., Harmsen, A., et al. (2001) · Nature Medicine · doi:10.1038/nm1101-1209 · Cited by 450
Cyclic ADP-Ribose in Insulin Secretion from Pancreatic βCells
Takasawa, S., Nata, K., Yonekura, H., & Okamoto, H. (1993) · Science · doi:10.1126/science.8420005 · Cited by 441
Physiological functions of cyclic ADP-ribose and NAADP as calcium messengers
Lee, H. C. (2001) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.41.1.317 · Cited by 433
Self-citationNew functions of a long‐known molecule: Emerging roles of NAD in cellular signaling
Ziegler, M. (2000) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.2000.01187.x · Cited by 289
Metadata
- Authors
- Galione, A., Lee, H. C., & Busa, W. B.
- Venue
- Science
- Published
- 1991-09-06
- Volume
- 253
- Issue
- 5024
- Pages
- 1143-1146
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2026571586
- Cited by
- 618
- References
- 2
- FWCI
- 17.18
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Ca 2+ -Induced Ca 2+ Release in Sea Urchin Egg Homogenates: Modulation by Cyclic ADP-Ribose. https://app.cochat.ai/papers/10.1126/science.1909457
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- Galione, A., Lee, H. C., & Busa, W. B. (1991). Ca 2+ -Induced Ca 2+ Release in Sea Urchin Egg Homogenates: Modulation by Cyclic ADP-Ribose. Science. https://doi.org/10.1126/science.1909457
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