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Cited by 428

The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.

Induction of Salmonella Stress Proteins Upon Infection of Macrophages

Buchmeier, Nancy A., Heffron, Fred·1990·Science

Abstract

Regulated expression of bacterial genes allows a pathogen to adapt to new environmental conditions within the host. The synthesis of over 30 Salmonella proteins is selectively induced during infection of macrophages. Two proteins induced by Salmonella are the heat shock proteins GroEL and DnaK. Two avirulent, macrophage-sensitive mutants of Salmonella synthesize GroEL and DnaK but fail to synthesize different subsets of proteins normally induced within the macrophage. Enhanced expression of selected Salmonella proteins contributes to bacterial survival within macrophages and may also contribute to the apparent immunodominance of heat shock proteins.

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Metadata

Authors
Buchmeier, N. A., & Heffron, F.
Venue
Science
Published
1990-05-11
Volume
248
Issue
4956
Pages
730-732
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2162559297
Cited by
428
References
21
FWCI
14.45
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Induction of Salmonella Stress Proteins Upon Infection of Macrophages. https://app.cochat.ai/papers/10.1126/science.1970672
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Buchmeier, N. A., & Heffron, F. (1990). Induction of Salmonella Stress Proteins Upon Infection of Macrophages. Science. https://doi.org/10.1126/science.1970672

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.