The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Dopamine Activation of an Orphan of the Steroid Receptor Superfamily
Abstract
The chicken ovalbumin upstream promoter transcription factor (COUP-TF) is a member of the steroid receptor superfamily and participates in the regulation of several genes. While a number of functions have been ascribed to COUP-TF, no ligand or activator molecule has been identified, and thus it is classified as one of a group of orphan receptors. Activation of COUP-TF by physiological concentrations of the neurotransmitter dopamine was observed in transient transfection assays. Treatment of transfected cells with the dopamine receptor agonist α-ergocryptine also activated COUP-dependent expression of a reporter gene. COUP-TF that contained a deletion in the COOH-terminal domain was not activated by these compounds. These observations suggest that dopamine may be a physiological activator of COUP-TF.
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Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Mlodzik, M., Hiromi, Y., Weber, U., Goodman, C. S., & Rubin, G. M. (1990) · Cell · doi:10.1016/0092-8674(90)90737-y · Cited by 457
Cited by
Unconventional Methods for Fabricating and Patterning Nanostructures
Xia, Y., Rogers, J. A., Paul, K. E., & Whitesides, G. M. (1999) · Chemical Reviews · doi:10.1021/cr980002q · Cited by 1,538
Schoonjans, K., Staels, B., & Auwerx, J. (1996) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)42003-6 · Cited by 1,216
Dopaminergic and Ligand-Independent Activation of Steroid Hormone Receptors
Power, R. F., Mani, S. K., Codina, J., Conneely, O. M., & O'Malley, B. W. (1991) · Science · doi:10.1126/science.1749936 · Cited by 567
Self-citationLaudet, V (1997) · Journal of Molecular Endocrinology · doi:10.1677/jme.0.0190207 · Cited by 557
Roles of steroid hormones and their receptors in structural organization in the nervous system
Kawata, M. (1995) · Neuroscience Research · doi:10.1016/0168-0102(96)81278-8 · Cited by 332
Metadata
- Authors
- Power, R. F., Lydon, J. P., Conneely, O. M., & O'Malley, B. W.
- Venue
- Science
- Published
- 1991-06-14
- Volume
- 252
- Issue
- 5012
- Pages
- 1546-1548
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2068025089
- Cited by
- 208
- References
- 2
- FWCI
- 9.12
- Type
- journal article
- Language
- en
- Open access
- closed
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- Power, R. F., Lydon, J. P., Conneely, O. M., & O'Malley, B. W. (1991). Dopamine Activation of an Orphan of the Steroid Receptor Superfamily. Science. https://doi.org/10.1126/science.2047861
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
