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Cited by 524

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Functional Organization of Primate Visual Cortex Revealed by High Resolution Optical Imaging

Ts'o, Daniel Y., Frostig, Ron D., Lieke, Edmund E., Grinvald, Amiram·1990·Science

Abstract

A high spatial resolution optical imaging system was developed to visualize cerebral cortical activity in vivo. This method is based on activity-dependent intrinsic signals and does not use voltage-sensitive dyes. Images of the living monkey striate (VI) and extrastriate (V2) visual cortex, taken during visual stimulation, were analyzed to yield maps of the distribution of cells with various functional properties. The cytochrome oxidase-rich blobs of V1 and the stripes of V2 were imaged in the living brain. In V2, no ocular dominance organization was seen, while regions of poor orientation tuning colocalized to every other cytochrome oxidase stripe. The orientation tuning of other regions of V2 appeared organized as modules that are larger and more uniform than those in V1.

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Crossref · 10.1126/science.2165630

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Metadata

Authors
Ts'o, D. Y., Frostig, R. D., Lieke, E. E., & Grinvald, A.
Venue
Science
Published
1990-07-27
Volume
249
Issue
4967
Pages
417-420
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2066057233
Cited by
524
References
1
FWCI
8.92
Type
journal article
Language
en
Open access
closed

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