The DOI matches its Crossref record; 34 of the 34 references it cites were found in a registry or an index.
Cloning of an Interleukin-3 Receptor Gene: a Member of a Distinct Receptor Gene Family
Abstract
Interleukin-3 (IL-3) binds to its receptor with high and low affinities, induces tyrosine phosphorylation, an d promotes the proliferation and differentiation of hematopoietic cells. A binding component of the IL-3 receptor was cloned. Fibroblasts transfected with the complementary DNA bound IL-3 with a low affinity [dissociation constant ( K d ) of 17.9 ± 3.6 n M ]. No consensus sequence for a tyrosine kinase was present in the cytoplasmic domain. Thus, additional components are required for a functional high affinity IL-3 receptor. A sequence comparison of the IL-3 receptor with other cytokine receptors (erythropoietin, IL-4, IL-6, and the β chain IL-2 receptor) revealed a common motif of a distinct receptor gene family.
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Citations
Cites
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Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
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Self-citationCloning and Expression of the Human Interleukin-6 (BSF-2/IFNβ 2) Receptor
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cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily
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Cited by
Molecular cloning and expression of an IL-6 signal transducer, gp130
Hibi, M., Murakami, M., Saito, M., Hirano, T., Taga, T., & Kishimoto, T. (1990) · Cell · doi:10.1016/0092-8674(90)90411-7 · Cited by 1,039
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Krantz, S. (1991) · Blood · doi:10.1182/blood.v77.3.419.419 · Cited by 855
Interleukin-6 and its receptor: a paradigm for cytokines
Kishimoto, T., Akira, S., & Taga, T. (1992) · Science · doi:10.1126/science.1411569 · Cited by 665
Kuroda, S., Fukata, M., Nakagawa, M., Fujii, K., Nakamura, T., Ookubo, T., Izawa, I., Nagase, T., Nomura, N., Tani, H., et al. (1998) · Science · doi:10.1126/science.281.5378.832 · Cited by 499
Self-citation
Metadata
- Authors
- Itoh, N., Yonehara, S., Schreurs, J., Gorman, D. M., Maruyama, K., Ishii, A., Yahara, I., Arai, K.-I., & Miyajima, A.
- Venue
- Science
- Published
- 1990-01-19
- Volume
- 247
- Issue
- 4940
- Pages
- 324-327
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2084424583
- Cited by
- 401
- References
- 34
- FWCI
- 37.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- Itoh, N., Yonehara, S., Schreurs, J., Gorman, D. M., Maruyama, K., Ishii, A., Yahara, I., Arai, K.-I., & Miyajima, A. (1990). Cloning of an Interleukin-3 Receptor Gene: a Member of a Distinct Receptor Gene Family. Science. https://doi.org/10.1126/science.2404337
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
