The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Identification of a Platelet Membrane Glycoprotein as a Falciparum Malaria Sequestration Receptor
Abstract
Infections with the human malaria parasite Plasmodium falciparum are characterized by sequestration of erythrocytes infected with mature forms of the parasite. Sequestration of infected erythrocytes appears to be critical for survival of the parasite and to mediate immunopathological abnormalities in severe malaria. A leukocyte differentiation antigen (CD36) was previously suggested to have a role in sequestration of malaria-infected erythrocytes. CD36 was purified from platelets, where it is known as GPIV, and was shown to be a receptor for binding of infected erythrocytes. Infected erythrocytes adhered to CD36 immobilized on plastic; purified CD36 exhibited saturable, specific binding to infected erythrocytes; and purified CD36 or antibodies to CD36 inhibited and reversed binding of infected erythrocytes to cultured endothelial cells and melanoma cells in vitro. The portion of the CD36 molecule that reverses cytoadherence may be useful therapeutically for rapid reversal of sequestration in cerebral malaria.
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Thrombospondin binds falciparum malaria parasitized erythrocytes and may mediate cytoadherence
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Plasmodium falciparum Maturation Abolishes Physiologic Red Cell Deformability
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Cited by
Su, X.-Z., Heatwole, V. M., Wertheimer, S. P., Guinet, F., Herrfeldt, J. A., Peterson, D. S., Ravetch, J. A., & Wellems, T. E. (1995) · Cell · doi:10.1016/0092-8674(95)90055-1 · Cited by 1,219
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Rapid switching to multiple antigenic and adhesive phenotypes in malaria
Roberts, D. J., Craig, Berendt, A. R., Pinches, R., Nash, G., Marsh, K., & Newbold, C. I. (1992) · Nature · doi:10.1038/357689a0 · Cited by 619
Biomechanics approaches to studying human diseases
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Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway.
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Metadata
- Authors
- Ockenhouse, C. F., Tandon, N. N., Magowan, C., Jamieson, G. A., & Chulay, J. D.
- Venue
- Science
- Published
- 1989-03-17
- Volume
- 243
- Issue
- 4897
- Pages
- 1469-1471
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2059917880
- Cited by
- 310
- References
- 13
- FWCI
- 30.80
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Identification of a Platelet Membrane Glycoprotein as a Falciparum Malaria Sequestration Receptor. https://app.cochat.ai/papers/10.1126/science.2467377
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- Ockenhouse, C. F., Tandon, N. N., Magowan, C., Jamieson, G. A., & Chulay, J. D. (1989). Identification of a Platelet Membrane Glycoprotein as a Falciparum Malaria Sequestration Receptor. Science. https://doi.org/10.1126/science.2467377
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
