The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Plasmodium falciparum Maturation Abolishes Physiologic Red Cell Deformability
Abstract
Normal red cells deform markedly as they pass through the spleen and the peripheral capillaries. In these studies, the effects of Plasmodium falciparum infection and maturation on the deformability of parasitized red cells exposed to fluid shear stress in vitro were examined by means of a rheoscope. Red cells containing the early (ring) erythrocytic stage of the parasite have impaired deformability at physiologic shear stresses, and recover their normal shape more slowly. Red cells containing more mature parasites (trophozoites or schizonts) exhibit no deformation under the same conditions. These results provide a mechanism to explain the ability of the spleen to remove parasitized red cells from the circulation of both immune and nonimmune hosts.
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Cites
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Cited by
World Health Organization (2000) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(00)90300-6 · Cited by 1,085
Biomechanics approaches to studying human diseases
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Diffraction phase microscopy: principles and applications in materials and life sciences
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Identification of a Platelet Membrane Glycoprotein as a Falciparum Malaria Sequestration Receptor
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Metadata
- Authors
- Cranston, H. A., Boylan, C. W., Carroll, G. L., Sutera, S. P., Williamson, J. R., Gluzman, I. Y., & Krogstad, D. J.
- Venue
- Science
- Published
- 1984-01-27
- Volume
- 223
- Issue
- 4634
- Pages
- 400-403
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2053758185
- Cited by
- 301
- References
- 21
- FWCI
- 8.96
- Type
- journal article
- Language
- en
- Open access
- closed
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- Cranston, H. A., Boylan, C. W., Carroll, G. L., Sutera, S. P., Williamson, J. R., Gluzman, I. Y., & Krogstad, D. J. (1984). Plasmodium falciparum Maturation Abolishes Physiologic Red Cell Deformability. Science. https://doi.org/10.1126/science.6362007
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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