The DOI matches its Crossref record; 40 of the 40 references it cites were found in a registry or an index.
Calcium-Regulated Phosphorylation Within the Leucine Zipper of C/EBPβ
Abstract
Alterations in intracellular calcium levels activate several signal transduction pathways resulting in distinct patterns of gene expression. Here, a pathway for calcium-mediated signals is demonstrated that involves C/EBPβ, a member of the bZip family of transcription factors. In pituitary cells C/EBPβ was phosphorylated in response to increased intracellular calcium concentrations as a consequence of the activation of a calcium-calmodulin— dependent protein kinase. Phosphorylation of serine at position 276 within the leucine zipper of C/EBPβ appeared to confer calcium-regulated transcriptional stimulation of a promoter that contained binding sites for C/EBPβ.
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Cites
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A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family.
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Cited by
Transcription Factors, Normal Myeloid Development, and Leukemia
Tenen, D. G., Hromas, R., Licht, J. D., & Zhang, D.-E. (1997) · Blood · doi:10.1182/blood.v90.2.489 · Cited by 735
The Role of C/EBP Isoforms in the Control of Inflammatory and Native Immunity Functions
Poli, V. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.45.29279 · Cited by 677
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
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Ca2+/CaM-Dependent Kinases: From Activation to Function
Hook, S. S., & Means, A. R. (2001) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev.pharmtox.41.1.471 · Cited by 482
Tsukada, J., Yoshida, Y., Kominato, Y., & Auron, P. E. (2011) · Cytokine · doi:10.1016/j.cyto.2010.12.019 · Cited by 317
Metadata
- Authors
- Wegner, M., Cao, Z., & Rosenfeld, M. G.
- Venue
- Science
- Published
- 1992-04-17
- Volume
- 256
- Issue
- 5055
- Pages
- 370-373
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2034856894
- Cited by
- 391
- References
- 40
- FWCI
- 15.91
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wegner, M., Cao, Z., & Rosenfeld, M. G. (1992). Calcium-Regulated Phosphorylation Within the Leucine Zipper of C/EBPβ. Science. https://doi.org/10.1126/science.256.5055.370
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
