The DOI matches its Crossref record; 189 of the 189 references it cites were found in a registry or an index.
Ca2+/CaM-Dependent Kinases: From Activation to Function
Abstract
Calmodulin (CaM) is an essential protein that serves as a ubiquitous intracellular receptor for Ca 2+. The Ca 2+/CaM complex initiates a plethora of signaling cascades that culminate in alteration of cellular functions. Among the many Ca 2+/CaM-binding proteins to be discovered, the multifunctional protein kinases CaMKI, II, and IV play pivotal roles. Our review focuses on this class of CaM kinases to illustrate the structural and biochemical basis for Ca 2+/CaM interaction with and regulation of its target enzymes. Gene transcription has been chosen as the functional endpoint to illustrate the recent advances in Ca 2+/CaM-mediated signal transduction mechanisms.
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Cites
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Global Analysis of Protein Activities Using Proteome Chips
Zhu, H., Bilgin, M., Bangham, R., Hall, D., Casamayor, A., Bertone, P., Lan, N., Jansen, R., Bidlingmaier, S., Houfek, T., et al. (2001) · Science · doi:10.1126/science.1062191 · Cited by 1,884
Structure–function of the multifunctional Ca2+/calmodulin-dependent protein kinase II
HUDMON, A., & SCHULMAN, H. (2002) · Biochemical Journal · doi:10.1042/bj20020228 · Cited by 615
Predominant α2/β2/γ3 AMPK activation during exercise in human skeletal muscle
Birk, J. B., & Wojtaszewski, J. F. P. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.120972 · Cited by 293
Hall, D. A., Ptacek, J., & Snyder, M. (2007) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2006.11.021 · Cited by 286
Rose, A. J., Kiens, B., & Richter, E. A. (2006) · The Journal of Physiology · doi:10.1113/jphysiol.2006.111757 · Cited by 247
Metadata
- Authors
- Hook, S. S., & Means, A. R.
- Venue
- Annual Review of Pharmacology and Toxicology
- Publisher
- Annual Reviews
- Published
- 2001-04
- Volume
- 41
- Issue
- 1
- Pages
- 471-505
- ISSN
- 0362-1642 (ISSN-L)
- 1545-4304
- OpenAlex
- W2165104370
- Cited by
- 482
- References
- 189
- FWCI
- 1.19
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
