The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Amplification of a Gene Related to Mammalian mdr Genes in Drug-Resistant Plasmodium falciparum
Abstract
The malaria parasite Plasmodium falciparum contains at least two genes related to the mammalian multiple drug resistance genes, and at least one of the P. falciparum genes is expressed at a higher level and is present in higher copy number in a strain that is resistant to multiple drugs than in a strain that is sensitive to the drugs.
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Citations
Cites
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Cited by
Contribution of the pfmdr1 gene to antimalarial drug-resistance
Duraisingh, M. T., & Cowman, A. F. (2005) · Acta Tropica · doi:10.1016/j.actatropica.2005.04.008 · Cited by 300
Genomic organization of the human multidrug resistance (MDR1) gene and origin of P-glycoproteins.
Chen, C. J., Clark, D., Ueda, K., Pastan, I., Gottesman, M. M., & Roninson, I. B. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)40260-3 · Cited by 269
The Plasmodium digestive Vacuole: Metabolic Headquarters and Choice Drug Target
Olliaro, P. L., & Goldberg, D. E. (1995) · Parasitology Today · doi:10.1016/0169-4758(95)80042-5 · Cited by 139
Metadata
- Authors
- Wilson, C. M., Serrano, A. E., Wasley, A., Bogenschutz, M. P., Shankar, A. H., & Wirth, D. F.
- Venue
- Science
- Published
- 1989-06-09
- Volume
- 244
- Issue
- 4909
- Pages
- 1184-1186
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2016102145
- Cited by
- 444
- References
- 1
- FWCI
- 45.69
- Type
- journal article
- Language
- en
- Open access
- closed
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- Wilson, C. M., Serrano, A. E., Wasley, A., Bogenschutz, M. P., Shankar, A. H., & Wirth, D. F. (1989). Amplification of a Gene Related to Mammalian mdr Genes in Drug-Resistant Plasmodium falciparum. Science. https://doi.org/10.1126/science.2658061
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
