The DOI matches its Crossref record; 6 of the 6 references it cites were found in a registry or an index.
The Galvanization of Biology: A Growing Appreciation for the Roles of Zinc
Abstract
Zinc ions are key structural components of a large number of proteins. The binding of zinc stabilizes the folded conformations of domains so that they may facilitate interactions between the proteins and other macromolecules such as DNA. The modular nature of some of these zinc-containing proteins has allowed the rational design of site-specific DNA binding proteins. The ability of zinc to be bound specifically within a range of tetrahedral sites appears to be responsible for the evolution of the wide range of zinc-stabilized structural domains now known to exist. The lack of redox activity for the zinc ion and its binding and exchange kinetics also may be important in the use of zinc for specific functional roles.
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Cites
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
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Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
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Regulating the fate of mRNA: the control of cellular iron metabolism
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Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers
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In vivo repression by a site-specific DNA-binding protein designed against an oncogenic sequence
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Iron metabolism-new perspectives in view
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Cited by
Femtomolar Sensitivity of Metalloregulatory Proteins Controlling Zinc Homeostasis
Outten, C. E., & O'Halloran, A. T. V. (2001) · Science · doi:10.1126/science.1060331 · Cited by 1,489
The ZIP family of metal transporters
Guerinot, M. L. (2000) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/s0005-2736(00)00138-3 · Cited by 1,200
Kambe, T., Tsuji, T., Hashimoto, A., & Itsumura, N. (2015) · Physiological Reviews · doi:10.1152/physrev.00035.2014 · Cited by 1,158
DNA Recognition by Cys2His2 Zinc Finger Proteins
Wolfe, S. A., Nekludova, L., & Pabo, C. O. (2000) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.29.1.183 · Cited by 1,053
Hambidge, M. (2000) · The Journal of Nutrition · doi:10.1093/jn/130.5.1344s · Cited by 773
Metadata
- Authors
- Berg, J. M., & Shi, Y.
- Venue
- Science
- Published
- 1996-02-23
- Volume
- 271
- Issue
- 5252
- Pages
- 1081-1085
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1992661805
- Cited by
- 1,929
- References
- 6
- FWCI
- 23.01
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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