The Physiological, Biochemical, and Molecular Roles of Zinc Transporters in Zinc Homeostasis and Metabolism

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Zinc at the crossroads of exercise and proteostasis

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The ZIP8/SIRT1 axis regulates alveolar progenitor cell renewal in aging and idiopathic pulmonary fibrosis

Liang, J., Huang, G., Liu, X., Taghavifar, F., Liu, N., Wang, Y., Deng, N., Yao, C., Xie, T., Kulur, V., et al. (2022) · Journal of Clinical Investigation · doi:10.1172/jci157338 · Cited by 98 · see citing works

Enhancing crop resilience by harnessing the synergistic effects of biostimulants against abiotic stress

Asif, A., Ali, M., Qadir, M., Karthikeyan, R., Singh, Z., Khangura, R. K., Gioia, F. D., & Ahmed, Z. F. R. (2023) · Frontiers in Plant Science · doi:10.3389/fpls.2023.1276117 · Cited by 96 · see citing works

Direct Comparison of Manganese Detoxification/Efflux Proteins and Molecular Characterization of ZnT10 Protein as a Manganese Transporter

Nishito, Y., Tsuji, N., Fujishiro, H., Takeda, T.-A., Yamazaki, T., Teranishi, F., Okazaki, F., Matsunaga, A., Tuschl, K., Rao, R., et al. (2016) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.728014 · Cited by 94 · see citing works

Zinc stimulates glucose oxidation and glycemic control by modulating the insulin signaling pathway in human and mouse skeletal muscle cell lines

Norouzi, S., Adulcikas, J., Sohal, S. S., & Myers, S. (2018) · PLoS ONE · doi:10.1371/journal.pone.0191727 · Cited by 95 · see citing works

A highly sensitive and selective fluorescent “off-on-off” relay chemosensor based on a new bis(salamo)-type tetraoxime for detecting Zn2+ and CN−

Liu, L.-Z., Wang, L., Yu, M., Zhao, Q. H., Zhang, Y., Sun, Y., & Dong, W. (2019) · Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy · doi:10.1016/j.saa.2019.117209 · Cited by 94 · see citing works

Double-edged effects and mechanisms of Zn 2+ microenvironments on osteogenic activity of BMSCs: osteogenic differentiation or apoptosis

Yu, Y., Liu, K., Wen, Z., Liu, W., Zhang, L., & Su, J. (2020) · RSC Advances · doi:10.1039/d0ra01465f · Cited by 93 · see citing works

Zinc regulates Nox1 expression through a NF-κB and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells

Salazar, G., Huang, J., Feresin, R. G., Zhao, Y., & Griendling, K. K. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.03.032 · Cited by 92 · see citing works

Bone Scaffolds: An Incorporation of Biomaterials, Cells, and Biofactors

Bahraminasab, M., Janmohammadi, M., Arab, S., Talebi, A., Nooshabadi, V. T., Koohsarian, P., & Nourbakhsh, M. S. (2021) · ACS Biomaterials Science & Engineering · doi:10.1021/acsbiomaterials.1c00920 · Cited by 90 · see citing works

Zinc and Central Nervous System Disorders

Wang, B., Fang, T., & Chen, H. (2023) · Nutrients · doi:10.3390/nu15092140 · Cited by 93 · see citing works

The metal face of protein tyrosine phosphatase 1B

Bellomo, E. A., Singh, K. B., Massarotti, A., Högstrand, C., & Maret, W. (2016) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2016.07.002 · Cited by 91 · see citing works

Phosphorylation of zinc channel ZIP7 drives MAPK, PI3K and mTOR growth and proliferation signalling

Nimmanon, T., Ziliotto, S., Morris, S., Flanagan, L., & Taylor, K. M. (2017) · Metallomics · doi:10.1039/c6mt00286b · Cited by 91 · see citing works

Channels, transporters and receptors for cadmium and cadmium complexes in eukaryotic cells: myths and facts

Thévenod, F., Fels, J., Lee, W., & Zarbock, R. (2019) · BioMetals · doi:10.1007/s10534-019-00176-6 · Cited by 88 · see citing works

Zinc transporters as potential therapeutic targets: An updated review

Hara, T., Yoshigai, E., Ohashi, T., & Fukada, T. (2021) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2021.11.007 · Cited by 89 · see citing works

Developing drugs targeting transition metal homeostasis

Weekley, C. M., & He, C. (2016) · Current Opinion in Chemical Biology · doi:10.1016/j.cbpa.2016.12.011 · Cited by 87 · see citing works

Hepatic ZIP14-mediated zinc transport is required for adaptation to endoplasmic reticulum stress

Kim, M., Aydemir, T. B., Kim, J.-H., & Cousins, R. J. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1704012114 · Cited by 87 · see citing works

Beyond zinc coordination: Bioimaging applications of Zn(II)-complexes

Kumar, N., Roopa, Bhalla, V., & Kumar, M. (2020) · Coordination Chemistry Reviews · doi:10.1016/j.ccr.2020.213550 · Cited by 87 · see citing works

Hyperglycemia-Induced Changes in ZIP7 and ZnT7 Expression Cause Zn2+ Release From the Sarco(endo)plasmic Reticulum and Mediate ER Stress in the Heart

Tuncay, E., Bitirim, C. V., Durak, A. T., Carrat, G., Taylor, K. M., Rutter, G. A., & Turan, B. (2017) · Diabetes · doi:10.2337/db16-1099 · Cited by 86 · see citing works

Zinc signaling and epilepsy

Doboszewska, U., Młyniec, K., Wlaź, A., Poleszak, E., Nowak, G., & Wlaź, P. (2019) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2018.08.013 · Cited by 81 · see citing works

Deficiency in the manganese efflux transporter SLC30A10 induces severe hypothyroidism in mice

Hutchens, S., Liu, C., Jursa, T., Shawlot, W., Dray, B. K., Yin, W., Gore, A. C., Aschner, M., Smith, D. R., & Mukhopadhyay, S. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m117.783605 · Cited by 84 · see citing works

Zinc Homeostasis in Platelet-Related Diseases

Mammadova‐Bach, E., & Braun, A. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20215258 · Cited by 85 · see citing works

Review on The Role of Zn2+ Ions in Viral Pathogenesis and the Effect of Zn2+ Ions for Host Cell-Virus Growth Inhibition

Ishida, T. (2019) · American Journal of Biomedical Science & Research · doi:10.34297/ajbsr.2019.02.000566 · Cited by 83 · see citing works

Zinc Status Alters Alzheimer's Disease Progression through NLRP3-Dependent Inflammation

Rivers‐Auty, J., Tapia, V. S., White, C., Daniels, M. J. D., Drinkall, S., Kennedy, P. T., Spence, H. G., Yu, S., Green, J., Hoyle, C., et al. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.1980-20.2020 · Cited by 84 · see citing works

Multifunctional role of zinc in human health: an update

Kiouri, D. P., Tsoupra, E., Peana, M., Perlepes, S. P., Stefanidou, M. E., & Chasapis, C. T. (2023) · EXCLI journal · doi:10.17179/excli2023-6335 · Cited by 83 · see citing works

Exposure of metal toxicity in Alzheimer’s disease: An extensive review

Islam, F., Shohag, S., Akhter, S., Islam, M. R., Sultana, S., Mitra, S., Chandran, D., Khandaker, M. U., Ashraf, G. M., Idris, A. M., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.903099 · Cited by 83 · see citing works

Iron and zinc exploitation during bacterial pathogenesis

Ma, L. M., Terwilliger, A. L., & Maresso, A. W. (2015) · Metallomics · doi:10.1039/c5mt00170f · Cited by 83 · see citing works

Zinc Transporters in Health and Disease

Kambe, T., Nishito, Y., & Fukue, K. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802168-2.00023-3 · Cited by 7 · see citing works

ZIP transporters‐regulated Zn 2+ homeostasis: A novel determinant of human diseases

Liu, H., Li, L., & Lu, R. (2024) · Journal of Cellular Physiology · doi:10.1002/jcp.31223 · Cited by 15 · see citing works

Overview of and Update on the Physiological Functions of Mammalian Zinc Transporters

Kambe, T. (2013) · Nippon Eiseigaku Zasshi (Japanese Journal of Hygiene) · doi:10.1265/jjh.68.92 · Cited by 13 · see citing works

Molecular and genetic features of zinc transporters in physiology and pathogenesis

Fukada, T., & Kambe, T. (2011) · Metallomics · doi:10.1039/c1mt00011j · Cited by 295 · see citing works

A structural perspective of transmembrane transport of zinc by ZnT and ZIP transporters

Xie, Q., Ding, J., Fu, C., Chen, X., Sun, Z., & Zhou, X. (2025) · Journal of Structural Biology · doi:10.1016/j.jsb.2025.108235 · Cited by 3 · see citing works