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Cited by 326

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Bimodal Interaction of Coatomer with the p24 Family of Putative Cargo Receptors

Fiedler, Klaus, Veit, Michael, Stamnes, Mark A., Rothman, James E.·1996·Science

Abstract

Cytoplasmic domains of members of the p24 family of putative cargo receptors were shown to bind to coatomer, the coat protein of COPI-coated transport vesicles. Domains that contained dilysine endoplasmic reticulum retrieval signals bound the α-, β′-, and ϵ-COP subunits of coatomer, whereas other p24 domains bound the β-, γ-, and ζ-COP subunits and required a phenylalanine-containing motif. Transit of a CD8-p24 chimera from the endoplasmic reticulum through the Golgi complex was slowed when the phenylalanine motif was mutated, suggesting that this motif may function as an anterograde transport signal. The either-or bimodal binding of coatomer to p24 tails suggests models for how coatomer can potentially package retrograde-directed and anterograde-directed cargo into distinct COPI-coated vesicles.

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Crossref · 10.1126/science.273.5280.1396

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Metadata

Authors
Fiedler, K., Veit, M., Stamnes, M. A., & Rothman, J. E.
Venue
Science
Published
1996-09-06
Volume
273
Issue
5280
Pages
1396-1399
ISSN
  • 0036-8075 (ISSN-L)
  • 1095-9203
OpenAlex
W2005672588
Cited by
326
References
1
FWCI
12.24
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Bimodal Interaction of Coatomer with the p24 Family of Putative Cargo Receptors. https://app.cochat.ai/papers/10.1126/science.273.5280.1396
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Fiedler, K., Veit, M., Stamnes, M. A., & Rothman, J. E. (1996). Bimodal Interaction of Coatomer with the p24 Family of Putative Cargo Receptors. Science. https://doi.org/10.1126/science.273.5280.1396

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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