Cited by 883

The DOI matches its Crossref record.

Control of EGF Receptor Signaling by Clathrin-Mediated Endocytosis

Vieira, Amandio V., Lamaze, Christophe, Schmid, Sandra L.·1996·Science

Abstract

Epidermal growth factor receptor (EGFR) signaling was analyzed in mammalian cells conditionally defective for receptor-mediated endocytosis. EGF-dependent cell proliferation was enhanced in endocytosis-defective cells. However, early EGF-dependent signaling events were not uniformly up-regulated. A subset of signal transducers required the normal endocytic trafficking of EGFR for full activation. Thus, endocytic trafficking of activated EGFR plays a critical role not only in attenuating EGFR signaling but also in establishing and controlling specific signaling pathways.

Overview

Integrity signals

Registry

Crossref · 10.1126/science.274.5295.2086

Cites

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Recomputing p-values needs the paper’s full text.

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Claims the paper makes

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Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The model suggests a role for Dab2 in mediating the endocytosis of signaling complexes and regulating signaling at the endosomes.

    “The model suggests a role for Dab2 in mediating the endocytosis of signaling complexes and regulating signaling at the endosomes”

    From Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice (2016) · cites this paper as Vieira et al., 1996

Citations

Cites

No references could be resolved yet.

Research works printed but not linked: 19

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  5. 10.1126/science.272.5270.1935 · DOI
  6. Lamaze C., Baba T., Redelmeier T. E., Schmid S. L., Mol. Biol. Cell 4, 715 (1993); · DOI
  7. 10.1083/jcb.129.1.47 · DOI
  8. 10.1126/science.272.5264.1008 · DOI · Paper page
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  11. 10.1083/jcb.127.4.915 · DOI
  12. Liu J.-P., Robinson P. J., Endocr. Rev. 16, 590 (1995);
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  14. 10.1016/S0021-9258(18)99131-3 · DOI
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  18. 10.1126/science.271.5255.1533 · DOI
  19. Lamaze C., Chuang T.-H., Terlecky L. J., Bokoch G. M., Schmid S. L., Nature 382, 177 (1996). · DOI

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Metadata

Authors
Vieira, A. V., Lamaze, C., & Schmid, S. L.
Affiliations
Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Venue
Science
Published
1996-12-20
Volume
274
Issue
5295
Pages
2086-2089
ISSN
  • 0036-8075
  • 1095-9203
Cited by
883
References
0
Language
en

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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