The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Trafficking of Matrix Collagens Through Bone-Resorbing Osteoclasts
Abstract
An intracellular pathway for proteins liberated from mineralized matrix during resorption was identified in osteoclasts. Analysis by confocal microscopy of sites of active bone resorption showed that released matrix proteins, including degraded type I collagen, were endocytosed along the ruffled border within the resorption compartment and transcytosed through the osteoclast to the basolateral membrane. Intracellular trafficking of degraded collagen, as typified by the resorbing osteoclast, may provide the cell with a regulatory mechanism for the control of tissue degradation.
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Citations
Cites
Protein Sorting by Transport Vesicles
Rothman, J. E., & Wieland, F. T. (1996) · Science · doi:10.1126/science.272.5259.227 · Cited by 1,153
Cell Surface Polarity in Epithelia
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Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts
Drake, F. H., Dodds, R. A., James, I. E., Connor, J. R., Debouck, C., Richardson, S., Lee-Rykaczewski, E., Coleman, L., Rieman, D., Barthlow, R., et al. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.21.12511 · Cited by 720
Proteolytic Activity of Human Osteoclast Cathepsin K
Bossard, M. J., Tomaszek, T. A., Thompson, S. K., Amegadzie, B. Y., Hanning, C. R., Jones, C., Kurdyla, J. T., McNulty, D. E., Drake, F. H., Gowen, M., et al. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.21.12517 · Cited by 498
Resorption of bone by isolated rabbit osteoclasts
Chambers, T. J., Revell, P. A., Fuller, K., & Athanasou, N. A. (1984) · Journal of Cell Science · doi:10.1242/jcs.66.1.383 · Cited by 413
Davies, J., Warwick, J., Totty, N., Philp, R., Helfrich, M., & Horton, M. (1989) · The Journal of cell biology · doi:10.1083/jcb.109.4.1817 · Cited by 365
Self-citationImmunoassay for quantifying type I collagen degradation products in urine evaluated
Bonde, M., Qvist, P., Fledelius, C., Riis, B. J., & Christiansen, C. (1994) · Clinical Chemistry · doi:10.1093/clinchem/40.11.2022 · Cited by 325
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The Ultrastructure of the Osteoclast and its Functional Implications
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The osteoclast clear zone is a specialized cell-extracellular matrix adhesion structure
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Self-citation
Cited by
Bone Resorption by Osteoclasts
Teitelbaum, S. L. (2000) · Science · doi:10.1126/science.289.5484.1504 · Cited by 3,962
Loss of the ClC-7 Chloride Channel Leads to Osteopetrosis in Mice and Man
Kornak, U., Kasper, D., Bösl, M. R., Kaiser, E., Schweizer, M., Schulz, A., Friedrich, W., Delling, G., & Jentsch, T. J. (2001) · Cell · doi:10.1016/s0092-8674(01)00206-9 · Cited by 995
Osteoclast–osteoblast communication
Matsuo, K., & Irie, N. (2008) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2008.03.027 · Cited by 780
Transcytosis: Crossing Cellular Barriers
TUMA, P. L., & HUBBARD, A. L. (2003) · Physiological Reviews · doi:10.1152/physrev.00001.2003 · Cited by 681
The cell biology of bone metabolism
Datta, H. K., Ng, W. F., Walker, J. A., Tuck, S. P., & Varanasi, S. S. (2008) · Journal of Clinical Pathology · doi:10.1136/jcp.2007.048868 · Cited by 614
Metadata
- Authors
- Nesbitt, S. A., & Horton, M. A.
- Venue
- Science
- Published
- 1997-04-11
- Volume
- 276
- Issue
- 5310
- Pages
- 266-269
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2058774752
- Cited by
- 375
- References
- 16
- FWCI
- 4.84
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.