The DOI matches its Crossref record.
In Vivo Endoscopic Optical Biopsy with Optical Coherence Tomography
Abstract
Current medical imaging technologies allow visualization of tissue anatomy in the human body at resolutions ranging from 100 micrometers to 1 millimeter. These technologies are generally not sensitive enough to detect early-stage tissue abnormalities associated with diseases such as cancer and atherosclerosis, which require micrometer-scale resolution. Here, optical coherence tomography was adapted to allow high-speed visualization of tissue in a living animal with a catheter-endoscope 1 millimeter in diameter. This method, referred to as “optical biopsy,” was used to obtain cross-sectional images of the rabbit gastrointestinal and respiratory tracts at 10-micrometer resolution.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Going deeper than microscopy: the optical imaging frontier in biology
Ntziachristos, V. (2010) · Nature Methods · doi:10.1038/nmeth.1483 · Cited by 1,896
Weissleder, R., & Mahmood, U. (2001) · Radiology · doi:10.1148/radiology.219.2.r01ma19316 · Cited by 1,315
Ultrahigh-resolution ophthalmic optical coherence tomography
Drexler, W., Morgner, U., Ghanta, R. K., Kärtner, F. X., Schuman, J. S., & Fujimoto, J. G. (2001) · Nature Medicine · doi:10.1038/86589 · Cited by 962
Self-citationAI in Medical Imaging Informatics: Current Challenges and Future Directions
Panayides, A. S., Amini, A., Filipovic, N. D., Sharma, A., Tsaftaris, S. A., Young, A., Foran, D., Do, N., Golemati, S., Kurc, T., et al. (2020) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2020.2991043 · Cited by 713
Simultaneous functional photoacoustic and ultrasonic endoscopy of internal organs in vivo
Yang, J.-M., Favazza, C., Chen, R., Yao, J., Cai, X., Maslov, K., Zhou, Q., Shung, K. K., & Wang, L. V. (2012) · Nature Medicine · doi:10.1038/nm.2823 · Cited by 429
Metadata
- Authors
- Tearney, G. J., Brezinski, M. E., Bouma, B. E., Boppart, S. A., Pitris, C., Southern, J. F., & Fujimoto, J. G.
- Venue
- Science
- Published
- 1997-06-27
- Volume
- 276
- Issue
- 5321
- Pages
- 2037-2039
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2036163000
- Cited by
- 1,364
- References
- 0
- FWCI
- 47.44
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: In Vivo Endoscopic Optical Biopsy with Optical Coherence Tomography. https://app.cochat.ai/papers/10.1126/science.276.5321.2037
- The paper
- Tearney, G. J., Brezinski, M. E., Bouma, B. E., Boppart, S. A., Pitris, C., Southern, J. F., & Fujimoto, J. G. (1997). In Vivo Endoscopic Optical Biopsy with Optical Coherence Tomography. Science. https://doi.org/10.1126/science.276.5321.2037
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
