Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

Sanchez, Yolanda, Wong, Calvin, Thoma, Richard S., Richman, Ron, Wu, Zhiqi, Piwnica-Worms, Helen, Elledge, Stephen J.·1997·Science
DOI 10.1126/science.277.5331.1497

Cited by (1,000)

Items 101–200 of 1,000

  1. A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase
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  2. Exploiting replicative stress to treat cancer
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  3. Caffeine inhibits the checkpoint kinase ATM
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  4. Nuclear Localization of Cyclin B1 Controls Mitotic Entry After DNA Damage
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  5. Phase I Trial of 72-Hour Continuous Infusion UCN-01 in Patients With Refractory Neoplasms
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  6. ATR: a master conductor of cellular responses to DNA replication stress
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  7. Positive Regulation of Wee1 by Chk1 and 14-3-3 Proteins
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  8. Control of the G2/M Transition
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  9. Caffeine Abolishes the Mammalian G2/M DNA Damage Checkpoint by Inhibiting Ataxia-Telangiectasia-mutated Kinase Activity
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  10. Phosphorylation‐dependent interactions between enzymes of plant metabolism and 14‐3‐3 proteins
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  11. ATM and ATR signaling at a glance
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  12. Cytoplasmic Localization of Human cdc25C during Interphase Requires an Intact 14-3-3 Binding Site
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  14. C-TAK1 Regulates Ras Signaling by Phosphorylating the MAPK Scaffold, KSR1
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  15. ATM: A mediator of multiple responses to genotoxic stress
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  16. Cell Cycle Control, Checkpoint Mechanisms, and Genotoxic Stress
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  17. DNA damage kinase signaling: checkpoint and repair at 30 years
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  18. A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage
    Alexandra L. Brown, Chang Hun Lee, Julie Kristina Schwarz, Nesanet Mitiku, Helen M. Piwnica-Worms, Jay H. Chung · 1999 · Proceedings of the National Academy of Sciences
  19. Identification of pathways regulating cell size and cell-cycle progression by RNAi
    Mikael Björklund, Minna Taipale, Markku T Varjosalo, Juha Saharinen, Juhani Lahdenperä, Jussi Taipale · 2006 · Nature
  20. Human Cyclin a Is Required for Mitosis until Mid Prophase
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  21. 14-3-3 Proteins—a focus on cancer and human disease
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  22. RNAi screen of the protein kinome identifies checkpoint kinase 1 (CHK1) as a therapeutic target in neuroblastoma
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  23. Functional interplay between ATM/ATR-mediated DNA damage response and DNA repair pathways in oxidative stress
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  24. Chk1 is haploinsufficient for multiple functions critical to tumor suppression
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  25. Involvement of the MKK6-p38γ Cascade in γ-Radiation-Induced Cell Cycle Arrest
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  26. Human Claspin Is Required for Replication Checkpoint Control
    Chini, Claudia Christiano Silva, Chen, Junjie · 2003 · Journal of Biological Chemistry
  27. Maintenance of G2 arrest in the Xenopus oocyte: a role for 14‐3‐3‐mediated inhibition of Cdc25 nuclear import
    Jing Yang, Katharine Winkler, Minoru Yoshida, Sally Kornbluth · 1999 · The EMBO Journal
  28. The Xenopus Chk1 Protein Kinase Mediates a Caffeine-sensitive Pathway of Checkpoint Control in Cell-free Extracts
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  29. Activated Polo-Like Kinase Plx1 Is Required at Multiple Points during Mitosis in Xenopus laevis
    Yuewei Qian, Eleanor ERIKSON, Chuan Li, James L. Maller · 1998 · Molecular and Cellular Biology
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  32. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Yuichi Hirose, Mitchel Stuart Berger, Russell O. Pieper · 2001 · PubMed
  33. DNA Damage Activates a Spatially Distinct Late Cytoplasmic Cell-Cycle Checkpoint Network Controlled by MK2-Mediated RNA Stabilization
    Hans Christian Reinhardt, Pia Hasskamp, Ingolf Schmedding, Sandra Morandell, Marcel A.T.M. van Vugt, XiaoZhe Wang, Rune Linding, Shao‐En Ong, David T. Weaver, Steven A. Carr et al. · 2010 · Molecular Cell
  34. An indolocarbazole inhibitor of human checkpoint kinase (Chk1) abrogates cell cycle arrest caused by DNA damage.
    Jeffrey R. Jackson, Aidan G. Gilmartin, Christina S. Imburgia, James D. Winkler, Lisa A. Marshall, Amy Roshak · 2000 · PubMed
  35. Plk3 Functionally Links DNA Damage to Cell Cycle Arrest and Apoptosis at Least in Part via the p53 Pathway
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  37. C-TAK1 protein kinase phosphorylates human Cdc25C on serine 216 and promotes 14-3-3 protein binding.
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  40. Temporal self-organization of the cyclin/Cdk network driving the mammalian cell cycle
    Claude Gérard, Albert Goldbeter · 2009 · Proceedings of the National Academy of Sciences
  41. Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1
    Alessandra Blasina, Jill F. Hallin, Enhong Chen, Maria E. Arango, Eugenia A. Kraynov, James Register, Stephan K. Grant, Sacha Ninkovic, Ping Chen, Tim Nichols et al. · 2008 · Molecular Cancer Therapeutics
  42. Redox Regulation of Cdc25C
    Pavel A. Savitsky, Toren Finkel · 2002 · Journal of Biological Chemistry
  43. Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways
    Nick Rhind, Paul R. Russell · 2000 · Journal of Cell Science
  44. Cdc25 Inhibited In Vivo and In Vitro by Checkpoint Kinases Cds1 and Chk1
    Beth A. Furnari, Alessandra Blasina, Michael Nicholas Boddy, Clare H. McGowan, Paul R. Russell · 1999 · Molecular Biology of the Cell
  45. ATR is a caffeine-sensitive, DNA-activated protein kinase with a substrate specificity distinct from DNA-PK
    Clare A Hall-Jackson, Darren A.E. Cross, Nick A. MORRICE, Carl Smythe · 1999 · Oncogene
  46. 14-3-3 Proteins Act as Negative Regulators of the Mitotic Inducer Cdc25 inXenopusEgg Extracts
    Akiko Kumagai, Peter S. Yakowec, William G. Dunphy · 1998 · Molecular Biology of the Cell
  47. G 2 arrest in Xenopus oocytes depends on phosphorylation of cdc25 by protein kinase A
    Brian C. Duckworth, Jennifer S. Weaver, JOAN V. RUDERMAN · 2002 · Proceedings of the National Academy of Sciences
  48. Radiosensitization of p53 mutant cells by PD0166285, a novel G(2) checkpoint abrogator.
    Yuli Wang, Jun Li, Robert N. Booher, Alan J. Kraker, Theodore Steven Lawrence, Wilbur R. Leopold, Yi Sun · 2001 · PubMed
  49. Involvement of the Interaction between p21 and Proliferating Cell Nuclear Antigen for the Maintenance of G2/M Arrest after DNA Damage
    Tomoaki Ando, Takumi Kawabe, Hirotaka Ohara, Bernard Ducommun, Makoto Itoh, Takashi Okamoto · 2001 · Journal of Biological Chemistry
  50. Checkpoint Pathways Come of Age
    Paul Nurse · 1997 · Cell
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    Melanie T. Hartsough, Deborah K. Morrison, Massimiliano Salerno, Diane Palmieri, Taoufik Ouatas, Michael Mair, J. Bosque Patrick, Patricia Schriver Steeg · 2002 · Journal of Biological Chemistry
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    Dong Xiao, Anna Herman-Antosiewicz, Jędrzej Antosiewicz, Hui Xiao, Marni Brisson, John Stephen Lazo, Shivendra Vikram Singh · 2005 · Oncogene
  53. Implications for Chk1 Regulation: The 1.7 Å Crystal Structure of Human Cell Cycle Checkpoint Kinase Chk1
    Ping Chen, Chun Luo, Yali Deng, Kevin Ryan, James Register, Stephen A. Margosiak, Anna Tempczyk-Russell, Binh Nguyen, Pamela Myers, Karen Lundgren et al. · 2000 · Cell
  54. Lats2, a putative tumor suppressor, inhibits G1/S transition
    Yunfang Li, Jing Pei, Xia Hong, Hengning Ke, Hongyan Wang, Wufan Tao · 2003 · Oncogene
  55. Human Homologs of Schizosaccharomyces pombe Rad1, Hus1, and Rad9 Form a DNA Damage-responsive Protein Complex
    Elias Volkmer, Larry M. Karnitz · 1999 · Journal of Biological Chemistry
  56. Cancer Risk and the ATM Gene: a Continuing Debate
    Kum Kum Khanna · 2000 · JNCI Journal of the National Cancer Institute
  57. Chk1 in the DNA damage response: conserved roles from yeasts to mammals
    Yinhuai Chen, Yolanda Sánchez · 2004 · DNA repair
  58. Cancer Drug Discovery and Development
    Jeffrey S. Humphrey, Karen Price, Elora Gupta, Andrew R. W. Baxter, John Bird, Daryl S. Sonnichsen, Joseph G. Naglich · 2003 · Humana Press eBooks
  59. GATA-1-Mediated Proliferation Arrest during Erythroid Maturation
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  60. Mechanisms of G2 Arrest in Response to Overexpression of p53
    William R. Taylor, Samuel E. DePrimo, Archana M. Agarwal, Munna L. Agarwal, Axel H. Schönthal, Karen S. Katula, George Robert Stark · 1999 · Molecular Biology of the Cell
  61. A Genome-wide CRISPR Screen Identifies CDC25A as a Determinant of Sensitivity to ATR Inhibitors
    Sergio Ruiz, Cristina Mayor‐Ruiz, Vanesa Lafarga, Matilde Murga, María Vega-Sendino, Sagrario Ortega, Óscar Fernández-Capetillo · 2016 · Molecular Cell
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  63. The checkpoint protein Chfr is a ligase that ubiquitinates Plk1 and inhibits Cdc2 at the G2 to M transition
    Dongmin Kang, James Chen, Jim Wong, G. Fang · 2002 · The Journal of Cell Biology
  64. Ultrasensitivity part II: multisite phosphorylation, stoichiometric inhibitors, and positive feedback
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  65. Utilization of Oriented Peptide Libraries to Identify Substrate Motifs Selected by ATM
    O'Neill, Ted, Dwyer, Alison J., Ziv, Yael, Chan, Doug W., Lees-Miller, Susan P., Abraham, Robert H., Lai, Jack H., Hill, David, Shiloh, Yossi, Cantley, Lewis C. et al. · 2000 · Journal of Biological Chemistry
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  67. Regulating the onset of mitosis
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  69. Role for the PP2A/B56δ Phosphatase in Regulating 14-3-3 Release from Cdc25 to Control Mitosis
    Seth S. Margolis, Jennifer A. Perry, Craig M. Forester, Leta K. Nutt, Yanxiang Guo, Melanie J. Jardim, Michael J. Thomenius, Christopher D. Freel, Rashid Darbandi, Jung‐Hyuck Ahn et al. · 2006 · Cell
  70. The mitotic peptidyl‐prolyl isomerase, Pin1, interacts with Cdc25 and Plx1
    Donna G. Crenshaw, Jing Yang, Anthony R. Means, Sally Kornbluth · 1998 · The EMBO Journal
  71. Claspin Operates Downstream of TopBP1 To Direct ATR Signaling towards Chk1 Activation
    Shizhou Liu, Simon Bekker‐Jensen, Niels Mailand, Claudia Lukas, Jiří Bártek, Jiri Lukas · 2006 · Molecular and Cellular Biology
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  74. Coupling of Homologous Recombination and the Checkpoint by ATR
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  75. The human decatenation checkpoint
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  76. A DNA Damage-Regulated BRCT-Containing Protein, TopBP1, Is Required for Cell Survival
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  77. Maintenance of genomic integrity by p53: complementary roles for activated and non-activated p53
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  79. Checkpoint control and cancer
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  80. Inhibition of Chk1-dependent G2 DNA damage checkpoint radiosensitizes p53 mutant human cells
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  82. Cdc25b and Cdc25c Differ Markedly in Their Properties as Initiators of Mitosis
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  83. The Drosophila ATM homologue Mei-41 has an essential checkpoint function at the midblastula transition
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  88. BRIT1/MCPH1 is a DNA damage responsive protein that regulates the Brca1–Chk1 pathway, implicating checkpoint dysfunction in microcephaly
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  89. Repeated phosphopeptide motifs in Claspin mediate the regulated binding of Chk1
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  90. Pin1 Acts Catalytically to Promote a Conformational Change in Cdc25
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  91. DNA damage response inhibitors: Mechanisms and potential applications in cancer therapy
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  95. INHIBITION OF LUNG CANCER CELL GROWTH BY QUERCETIN GLUCURONIDES VIA G2/M ARREST AND INDUCTION OF APOPTOSIS
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  98. Mitotic DNA damage and replication checkpoints in yeast
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  99. Evidence That the ATR/Chk1 Pathway Maintains Normal Replication Fork Progression during Unperturbed S Phase
    Eva Petermann, Keith W. Caldecott · 2006 · Cell Cycle
  100. Inhibition of Polo-like Kinase-1 by DNA Damage Occurs in an ATM- or ATR-dependent Fashion
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