Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

Sanchez, Yolanda, Wong, Calvin, Thoma, Richard S., Richman, Ron, Wu, Zhiqi, Piwnica-Worms, Helen, Elledge, Stephen J.·1997·Science

DOI 10.1126/science.277.5331.1497

Cited by (1,000)

Items 701–800 of 1,000

Synthetic lethal approaches for assessing combinatorial efficacy of chemotherapeutic drugs
Rebecca A. Jackson, Ee Sin Chen · 2016 · Pharmacology & Therapeutics
Chk1 and 14‐3‐3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest
Ruixue Yuan, Harmjan R. Vos, Robert M. van Es, Jing Chen, Boudewijn M.T. Burgering, Bart Westendorp, Alain de Bruin · 2018 · The EMBO Journal
CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice
Hironori Abe, Kris G. Alavattam, Yasuko Kato, Diego H. Castrillón, Qishen Pang, Paul R. Andreassen, Satoshi H. Namekawa · 2018 · Human Molecular Genetics
Interaction of checkpoint kinase 1 and the X‐linked inhibitor of apoptosis during mitosis
Verónica Galván, Alexei V. Kurakin, Dale E. Bredesen · 2004 · FEBS Letters
Critical Role of the Phosphatidylinositol 3-Kinase/Akt/Glycogen Synthase Kinase-3β Signaling Pathway in Recovery from Anthrax Lethal Toxin-induced Cell Cycle Arrest and MEK Cleavage in Macrophages
Soon-Duck Ha, Dennis Ng, Steven Pelech, Sung Ouk Kim · 2007 · Journal of Biological Chemistry
G2 DNA Damage Checkpoint Inhibition and Antimitotic Activity of 13-Hydroxy-15-oxozoapatlin
Natalie T. Rundle, Lin Xu, Raymond J. Andersen, Michel Roberge · 2001 · Journal of Biological Chemistry
Identification and characterization of polymorphic variations of the ataxia telangiectasia mutated (ATM) gene in childhood Hodgkin disease
Masatoshi Takagi · 2003 · Blood
Phosphorylation ofXenopusRad1 and Hus1 Defines a Readout for ATR Activation That Is Independent of Claspin and the Rad9 Carboxy Terminus
Patrick J. Lupardus, Karlene A. Cimprich · 2006 · Molecular Biology of the Cell
Cell Cycle Control
Vivien J. Tannoch, Phil W. Hinds, Li‐Huei Tsai · 2002 · Advances in experimental medicine and biology
Phase I study of LY2603618, a CHK1 inhibitor, in combination with gemcitabine in Japanese patients with solid tumors
Toshihiko Doi, Takayuki Yoshino, Kohei Shitara, Nobuaki Matsubara, Nozomu Fuse, Yoichi Naito, Kazunori Uenaka, Takashi Nakamura, Scott M. Hynes, Aimee K. Bence · 2015 · Anti-Cancer Drugs
Targeting the wee1 kinase for treatment of pediatric Down syndrome acute myeloid leukemia
J. Timothy Caldwell, Holly J. Edwards, Steven A. Buck, Yubin Ge, Jeffrey Warren Taub · 2014 · Pediatric Blood & Cancer
Expression of PDZ-binding kinase (PBK) is regulated by cell cycle-specific transcription factors E2F and CREB/ATF
Asit K. Nandi, Aaron P. Rapoport · 2005 · Leukemia Research
Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer
Shih‐Hung Yang, Ting‐Chun Kuo, Hsu Wu, Jhe‐Cyuan Guo, Chiun Hsu, Chih‐Hung Hsu, Yu‐Wen Tien, Kun‐Huei Yeh, Ann‐Lii Cheng, Sung‐Hsin Kuo · 2016 · World Journal of Gastroenterology
Deciphering the Acute Cellular Phosphoproteome Response to Irradiation with X-rays, Protons and Carbon Ions
Martin Winter, Ivana Đokić, Julian Schlegel, Uwe H. Warnken, Jürgen Debus, Amir Abdollahi, Martina Schnölzer · 2017 · Molecular & Cellular Proteomics
Tissue-Specific and Ubiquitous Expression Patterns from Alternative Promoters of Human Genes
Edwin H. Jacox, Valer Gotea, Ivan Ovcharenko, Laura L. Elnitski · 2010 · PLoS ONE
Small interfering RNA targeting CDC25B inhibits liver tumor growth in vitro and in vivo
Xinrui Yan, Mei‐Sze Chua, Jing He, Samuel K. So · 2008 · Molecular Cancer
Arabidopsis T-DNA insertional lines for CDC25 are hypersensitive to hydroxyurea but not to zeocin or salt stress
Natasha Damiana Spadafora, John H. Doonan, Robert J. Herbert, Maria Beatrice Bitonti, Emily Wallace, Hilary Joan Rogers, Dennis A. Francis · 2010 · Annals of Botany
Schizosaccharomyces pombe Checkpoint Response to DNA Interstrand Cross-Links
Sarah Lambert, Sarah J. Mason, Louise J. Barber, John Anthony Hartley, Jackie A. Pearce, Antony M. Carr, Peter J. McHugh · 2003 · Molecular and Cellular Biology
Physapubescin B Exhibits Potent Activity against Human Prostate Cancer In Vitro and In Vivo
Wanjing Ding, Zhijuan Hu, Zhewen Zhang, Qiaoqiao Ma, Huifang Tang, Zhongjun Ma · 2015 · Journal of Agricultural and Food Chemistry
Role of p21Waf-1 in Regulating the G1 and G2/M Checkpoints in Ultraviolet-Irradiated Keratinocytes
Tomoko Maeda, Michelle T. Chong, Robin A. Espino, Prescillia Chua, Jefferey Q. Cao, Eugene G. Chomey, Le Luong, Victor A. Tron · 2002 · Journal of Investigative Dermatology
Altered cell cycle response of drug-resistant lung carcinoma cells to doxorubicin
Colette O’Loughlin, Mary Heenan, S Coyle, MARTIN M. CLYNES · 2000 · European Journal of Cancer
Polo‐like kinase 1 regulates mitotic arrest after UV irradiation through dephosphorylation of p53 and inducing p53 degradation
Jie Chen, Gu Dai, Yiqian Wang, Sheng Wang, Feiyan Pan, Bin Xue, Donghong Zhao, Chaojun Li · 2006 · FEBS Letters
Chk1 frameshift mutation in sporadic and hereditary non-polyposis colorectal cancers with microsatellite instability
C.J. Kim, J.H. Lee, Jae Whie Song, Y.G. Cho, Sin‐Young Kim, S.W. Nam, Nam Jin Yoo, Won Sang Park, J.Y. Lee · 2007 · European Journal of Surgical Oncology
Abrogation of Chk1-mediated S/G2 checkpoint by UCN-01 enhances ara-C-induced cytotoxicity in human colon cancer cells.
Rong-Guangshao, Chun-XiaCAO, YvesPOMMIER · 2004 · PubMed
Generation of an indestructible cyclin B1 by caspase-6-dependent cleavage during mitotic catastrophe
Ying Wai Chan, Y Chen, Randy Y.C. Poon · 2008 · Oncogene
Transcriptional Regulation Is a Major Controller of Cell Cycle Transition Dynamics
Alessandro Romanel, Lars Juhl Jensen, Luca Cardelli, Attila Csikász‐Nagy · 2012 · PLoS ONE
Phase I Studies of CBP501, a G2 Checkpoint Abrogator, as Monotherapy and in Combination with Cisplatin in Patients with Advanced Solid Tumors
Geoffrey Ira Shapiro, Raoul Tibes, Michael S. Gordon, Bryan Y. Wong, Joseph P. Eder, Mitesh J. Borad, David S. Mendelson, Nicholas J. Vogelzang, Bruno R. Bastos, Glen J. Weiss et al. · 2011 · Clinical Cancer Research
Regulation of Cell Division
Andreas Heim, Beata Rymarczyk, Thomas U. Mayer · 2016 · Advances in experimental medicine and biology
NF‐κB pathway is involved in griseofulvin‐induced G2/M arrest and apoptosis in HL‐60 cells
Yih‐Huei Uen, Der-Zen Liu, Meng‐Shih Weng, Yuan‐Soon Ho, Shyr‐Yi Lin · 2007 · Journal of Cellular Biochemistry
Induction of a caffeine-sensitive S-phase cell cycle checkpoint by psoralen plus ultraviolet A radiation
Christoph Joerges, Inge Kuntze, Thomas Herzinge · 2003 · Oncogene
DNA replication checkpoint control
Nevels Michael · 1999 · Frontiers in bioscience
Targeting CDKs in cancer therapy: advances in PROTACs and molecular glues
Hany E. S. Marei, Khaled Bedair, Anwarul Hasan, Layla Al-Mansoori, Alice Gaiba, Andrea Morrione, Carlo Cenciarelli, Antonio Giordano · 2025 · npj Precision Oncology
Phosphorylation of proliferating cell nuclear antigen promotes cancer progression by activating the ATM/Akt/GSK3β/Snail signaling pathway
Bo Peng, Janice Ortega, Liya Gu, Zhijie Chang, Guo‐Min Li · 2019 · Journal of Biological Chemistry
Targeting Non-Oncogene Addiction for Cancer Therapy
Hae Ryung Chang, Eunyoung Jung, Soobin Cho, Young-Jun Jeon, Yonghwan Kim · 2021 · Biomolecules
The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma
Hidenori Machino, Syuzo Kaneko, Masaaki Komatsu, Noriko Ikawa, Ken Asada, Ryuichiro Nakato, Kanto Shozu, Ai Dozen, Kenbun Sone, Hiroshi Yoshida et al. · 2022 · Communications Biology
Pectenotoxin-2 from Marine Sponges: A Potential Anti-Cancer Agent—A Review
Gi‐Young Kim, Wun‐Jae Kim, Yung Hyun Choi · 2011 · Marine Drugs
Radiation-induced Phosphorylation of Chk1 at S345 is Associated with p53-dependent Cell Cycle Arrest Pathways
Hui Tian, Alexander T. Faje, Siu Lan Lee, Timothy J. Jorgensen · 2002 · Neoplasia
Molecular switches that govern the balance between proliferation and apoptosis
B. Schütte, Frans C. S. Ramaekers · 2000 · Springer eBooks
Cooperative function of Chk1 and p38 pathways in activating G2 arrest following exposure to temozolomide
Yuichi Hirose, Makoto Katayama, Mitchel Stuart Berger, Russell O. Pieper · 2004 · Journal of neurosurgery
Different G2/M accumulation in M059J and M059K cells after exposure to DNA double-strand break–inducing agents
Åsa Holgersson, Thomas Heiden, Juan Castro, Margareta Edgren, Rolf Lewensohn, Annelie E. Meijer · 2005 · International Journal of Radiation Oncology*Biology*Physics
Reovirus-Induced Alterations in Gene Expression Related to Cell Cycle Regulation
George J. Poggioli, Roberta L. DeBiasi, Ryan J. Bickel, Robert M. Jotte, Aaron C. Spalding, Gary L. Johnson, Kenneth L. Tyler · 2002 · Journal of Virology
HIV-1 viral protein R (Vpr) & host cellular responses.
Yuqi Zhao, Michael Bukrinsky, Robert T. Elder · 2005 · PubMed
Diverse nuclear transport pathways regulate cell proliferation and oncogenesis
Jennifer K. Hood, Pamela A. Silver · 2000 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Interplay Between the Cell Cycle and Double-Strand Break Response in Mammalian Cells
Kate Beishline, Jane Azizkhan‐Clifford · 2014 · Methods in molecular biology
Genetic variants of CHEK1 , PRIM2 and CDK6 in the mitotic phase‐related pathway are associated with nonsmall cell lung cancer survival
Rui Mu, Hongliang Liu, Sheng Luo, Edward F. Patz, Carolyn Glass, Li Su, Mulong Du, David C. Christiani, Lei Jin, Qingyi Wei · 2021 · International Journal of Cancer
Inhibition of Chk2 promotes neuroprotection, axon regeneration, and functional recovery after CNS injury
Matthew J. Taylor, Adam M. Thompson, Sharif Alhajlah, Richard I. Tuxworth, Zubair Ahmed · 2022 · Science Advances
Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis
Andrea Lunardi, Shohreh Varmeh, Ming Chen, Riccardo Taulli, Jlenia Guarnerio, Ugo Ala, Nina Seitzer, Tomoki Ishikawa, Brett Stewart Carver, Robin M. Hobbs et al. · 2015 · Cancer Discovery
14-3-3σ and Its Modulators in Cancer
Ghazi Aljabal, Beow Keat Yap · 2020 · Pharmaceuticals
Increased expression of CHK2 in human gastric carcinomas harboring p53 mutations
Hideo Shigeishi, Hiroshi Yokozaki, Naohide Oue, Hiroki Kuniyasu, Tomohiro Kondo, Takenori Ishikawa, Wataru Yasui · 2002 · International Journal of Cancer
Negative Growth Regulation of SK-N-MC Cells by bFGF Defines a Growth Factor-sensitive Point in G2
Veronique A. J. Smits, Maartje A. van Peer, Marieke A. G. Essers, Rob Klompmaker, Gert Rijksen, René H. Medema · 2000 · Journal of Biological Chemistry
Human and Mouse Homologs of theSchizosaccharomyces pombe rad17Cell Cycle Checkpoint Control Gene
Hans A.R. Bluyssen, Nicole C. Naus, Roselinde I. van Ravestein-van Os, Iris Jaspers-Dekker, Jan H.J. Hoeijmakers, Annelies de Klein · 1999 · Genomics
Targeting lung cancer through inhibition of checkpoint kinases
Randi G. Syljuåsen, Grete Hasvold, Sissel Hauge, Åslaug Helland · 2015 · Frontiers in Genetics
Dominant mutations in CHK1 cause pronuclear fusion failure and zygote arrest that can be rescued by CHK1 inhibitor
Honghui Zhang, Tailai Chen, Keliang Wu, Zhenzhen Hou, Shigang Zhao, Chuanxin Zhang, Yuan Gao, Ming Jun Gao, Zi‐Jiang Chen, Han Zhao · 2021 · Cell Research
Improving the selectivity of cancer treatments by interfering with cell response pathways
Giovanna L.M. Damia, Massimo Broggini · 2004 · European Journal of Cancer
Gene- and genome-based analysis of significant codon patterns in yeast, rat and mice genomes with the CUT Codon UTilization tool
Francis Doyle, Andrea Leonardi, Lauren Endres, Scott A. Tenenbaum, Peter C. Dedon, Thomas J. Begley · 2016 · Methods
Hijacking oocyte DNA repair machinery in transgenesis?
Anthony C.F. Perry · 2000 · Molecular Reproduction and Development
Etoposide and Adriamycin but Not Genistein Can Activate the Checkpoint Kinase Chk2 Independently of ATM/ATR
Delphine Théard, Marjorie Coisy‐Quivy, Bernard Ducommun, PATRICK J. CONCANNON, Jean-Marie Darbon · 2001 · Biochemical and Biophysical Research Communications
Overexpression of Cyclin A Inhibits Augmentation of Recombinant Adeno-Associated Virus Transduction by the Adenovirus E4orf6 Protein
Mirta Grifman, Nancie N. Chen, Guangping Gao, Toni Cathomen, James M. Wilson, Matthew D. Weitzman · 1999 · Journal of Virology
UVB induced cell cycle checkpoints in an early stage human melanoma line, WM35
Teresa Petrocelli, Joyce M. Slingerland · 2000 · Oncogene
Protein phosphatases: Structure, regulation, and function
Sheng Luan · 2000 · Advances in botanical research
RAD1,a Human Structural Homolog of theSchizosaccharomyces pombe RAD1Cell Cycle Checkpoint Gene
Upendra K. Marathi, Maria Dahlén, Per Sunnerhagen, Alejandra V. Romero, Louis S. Ramagli, Michael J. Siciliano, Lei Li, Randy J. Legerski · 1998 · Genomics
Phosphorylation of CDC25C by AMP-activated protein kinase mediates a metabolic checkpoint during cell-cycle G2/M-phase transition
Yuqing Shen, John William Sherman, Xuyong Chen, Ruoning Wang · 2018 · Journal of Biological Chemistry
Gene 33/Mig6/ERRFI1, an Adapter Protein with Complex Functions in Cell Biology and Human Diseases
Dazhong Xu, Cen Li · 2021 · Cells
An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cells
Nathalie Cahuzac, Aurélie Studény, Kris S. Marshall, Isabella Versteege, Kate Wetenhall, Bruno Pfeiffer, Stéphane Léonce, John A. Hickman, Alain Pierré, Roy M. Golsteyn · 2009 · Cancer Letters
HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1
Niko Moses, Mu Zhang, Jheng-Yu Wu, Hu Chen, Shengyan Xiang, Agnes Malysa, Hyejeong Jang, Wei Chen, Wenlong Bai, Gerold Bepler et al. · 2020 · Cells
Inhibition of CDC2/Cyclin B1 in response to selenium-induced oxidative stress during spermatogenesis: potential role of Cdc25c and p21
Naveen Kaushal, M. P. Bansal · 2006 · Molecular and Cellular Biochemistry
Effects of ethanol on hepatic cellular replication and cell cycle progression
Dahn L. Clemens · 2007 · World Journal of Gastroenterology
The G2 checkpoint activated by DNA damage does not prevent genome instability in plant cells
Jesús A. Carballo, Juana Pincheira, Consuelo de la Torre · 2006 · Biological Research
Characterization of brain PCTAIRE‐1 kinase immunoreactivity and its interactions with p11 and 14‐3‐3 proteins
Françoise Le Bouffant, Joël Capdevielle, Jean-Claude Guillemot, Fritz A.J. Sladeczek · 1998 · European Journal of Biochemistry
Polo-like kinases in cell cycle checkpoint control
Wei Hao Dai · 2003 · Frontiers in bioscience
The SKP2 ‐p27 axis defines susceptibility to cell death upon CHK1 inhibition
Michael Lohmüller, Bernhard F. Roeck, Tamás Géza Szabó, Marina A. Schapfl, Fragka Pegka, Sebastian Herzog, Andreas Villunger, Fabian Schuler · 2022 · Molecular Oncology
Effect of neutron capture therapy on the cell cycle of human squamous cell carcinoma cells
Akitoshi Kamida, Yusei Fujita, Itsuro Kato, Soichi Iwai, Koji Ono, Minoru Suzuki, Yoshinori Sakurai, Yoshiaki Yura · 2008 · International Journal of Radiation Biology
Regulation of the Aurora-A gene following topoisomerase I inhibition: implication of the Myc transcription Factor
Sandy Courapied, Julia Cherier, Arnaud M. Vigneron, Marie‐Bérengère Troadec, Sandrine Giraud, Isabelle Valo, Claude Prigent, Erick C. Gamelin, Olivier Coqueret, Benjamin Barré · 2010 · Molecular Cancer
Antitumor Imidazolyl Disulfide IV-2 Causes Irreversible G2/M Cell Cycle Arrest without Hyperphosphorylation of Cyclin-Dependent Kinase Cdk1
Andreas Vogt, Kenji Tamura, Shawndra Watson, John Stephen Lazo · 2000 · Journal of Pharmacology and Experimental Therapeutics
Human parvovirus B19-induced cell cycle arrest and apoptosis
Eiji Morita, Kazuo Sugamura · 2002 · Springer Seminars in Immunopathology
Ensuring the Stability of the Genome: DNA Damage Checkpoints
Christine Latif, Susan H Harvey, Susan J. O'Connell · 2001 · The Scientific World JOURNAL
Mitotic catastrophe induced by exposure of V79 Chinese hamster cells to low-energy protons
R. CHERUBINI F. IANZINI · 1999 · International Journal of Radiation Biology
Inhibition of cell proliferation by lithium is associated with interference in cdc2 activation
Veronique A. J. Smits, Marieke A. G. Essers, Dominique S.E Loomans, Rob Klompmaker, Gert Rijksen, René H. Medema · 1999 · FEBS Letters
Differential Regulation of Growth and Checkpoint Control Mediated by a Cdc25 Mitotic Phosphatase from Pneumocystis carinii
Michael P. Gustafson, Charles F. Thomas, Frank M. Rusnak, ANDREW HAR LIMPER, Edward B. Leof · 2001 · Journal of Biological Chemistry
Functional localization of a melanoma tumor suppressor gene to a small (≤2 Mb) region on 11q23
Gavin P. Robertson, Eleonora K. Goldberg, TRACY GROSS LUGO, Jane W. Fountain · 1999 · Oncogene
The DNA Damage Checkpoint and Human Cancer
Linda Brooke Schultz, Nabil H. Chehab, Asra Malikzay, Richard A. DiTullio, Elena S. Stavridi, Thanos D. Halazonetis · 2000 · Cold Spring Harbor Symposia on Quantitative Biology
DNA Damage Checkpoint
Werner Dubitzky, Olaf Wolkenhauer A, Kwang‐Hyun Cho, Hiroki Yokota · 2013 · Springer eBooks
Induction of G2/M arrest by pseudolaric acid B is mediated by activation of the ATM signaling pathway
Aiguo Meng, Lingling Jiang · 2009 · Acta Pharmacologica Sinica
Hsp90-inhibitor geldanamycin abrogates G2 arrest in p53-negative leukemia cell lines through the depletion of Chk1
Koichi Sugimoto, Makoto Sasaki, Yasushi Isobe, M Tsutsui, Hiroko Suto, Jun Ando, Kenji Tamayose, Miki Ando, Kazuo Oshimi · 2007 · Oncogene
Exercising Restraints: Role of Chk1 in Regulating the Onset and Progression of Unperturbed Mitosis in Vertebrate Cells
George Zachos, David A. Gillespie · 2007 · Cell Cycle
Nuclear Receptor Corepressor 1 Expression and Output Declines with Prostate Cancer Progression
Sandra M. Lopez, Alexander I. Agoulnik, Manqi Zhang, Leif E. Peterson, Egla Suarez, Gregory A. Gandarillas, Anna Frolov, Rile Li, Kimal Rajapakshe, Christian Coarfa et al. · 2016 · Clinical Cancer Research
An account of fungal 14-3-3 proteins
Ravinder Kumar · 2017 · European Journal of Cell Biology
ATR signaling in mammalian meiosis: From upstream scaffolds to downstream signaling
Catalina Pereira, Marcus Bustamante Smolka, Robert S. Weiss, Miguel A. Brieño‐Enríquez · 2020 · Environmental and Molecular Mutagenesis
XRad17 Is Required for the Activation of XChk1 But Not XCds1 during Checkpoint Signaling inXenopus
Rhiannon E. Jones, J. Ross Chapman, Chandrakala Puligilla, Johanne M. Murray, Antony M. Car, Christopher C. Ford, Howard D. Lindsay · 2003 · Molecular Biology of the Cell
Phosphorylation of ATR-Interacting Protein on Ser239 Mediates an Interaction with Breast-Ovarian Cancer Susceptibility 1 and Checkpoint Function
Monica Venere, Andrew R. Snyder, Omar Zgheib, Thanos D. Halazonetis · 2007 · Cancer Research
Proteasome-dependent degradation of human CDC25B phosphatase
Christophe Cans, Bernard Ducommun, Véronique Baldin · 1999 · Molecular Biology Reports
The Aryl Hydrocarbon Receptor in the Pathogenesis of Environmentally-Induced Squamous Cell Carcinomas of the Skin
Christian Vogeley, Katharina Maria Rolfes, Jean Krutmann, Thomas Haarmann‐Stemmann · 2022 · Frontiers in Oncology
Two‐fold elevation of expression of FoxM1 transcription factor in mouse embryonic fibroblasts enhances cell cycle checkpoint activity by stimulating p21 and Chk1 transcription
Yongjun Tan, Y. Chen, L. Yu, Hong Zhu, Xiangbing Meng, X. Huang, Liping Meng, Miao Ding, Zhangchi Wang, Ling Shan · 2010 · Cell Proliferation
Pim‐1 kinase as activator of the cell cycle pathway in neuronal death induced by DNA damage
Yi Zhang, Mohammad Parsanejad, En Huang, Dianbo Qu, Hossein Aleyasin, Maxime W.C. Rousseaux, Yasmilde Rodríguez González, Sean P. Cregan, Ruth S. Slack, David S. Park · 2009 · Journal of Neurochemistry
Alteration of G2 Cell Cycle Regulators Occurs during Carcinogenesis of the Endometrium
Hiroshi Tsuda, Yasunori Hashiguchi, Takeshi Inoue, Kumio Yamamoto · 2003 · Oncology
Intramolecular autoinhibition of checkpoint kinase 1 is mediated by conserved basic motifs of the C-terminal kinase–associated 1 domain
Ryan P. Emptage, Megan J. Schoenberger, Kathryn M. Ferguson, Ronen Marmorstein · 2017 · Journal of Biological Chemistry
Replication stress: Driver and therapeutic target in genomically instable cancers
Pepijn M. Schoonen, Sergi Guerrero Llobet, Marcel A.T.M. van Vugt · 2018 · Advances in protein chemistry and structural biology
DNA Damage Mediated S and G2 Checkpoints in Human Embryonal Carcinoma Cells
Xiaoqi Wang, Vincent Chi Hang Lui, Ronnie T. P. Poon, Ping Lü, Randy Y.C. Poon · 2009 · Stem Cells
Human Immunodeficiency Virus Type 1 Vpr Induces Cell Cycle G 2 Arrest through Srk1/MK2-Mediated Phosphorylation of Cdc25
Sylvain Huard, Robert T. Elder, Dong Liang, Ge Li, Yuqi Zhao · 2007 · Journal of Virology
DNA-damage sensitizers: Potential new therapeutical tools to improve chemotherapy
David Michod, Christian Widmann · 2007 · Critical Reviews in Oncology/Hematology