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Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

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Fission yeast chkl protein kinase links the rad checkpoint pathway to cdc2

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Chk1 is a wee1 kinase in the G2 DNA damage checkpoint inhibiting cdc2 by Y15 phosphorylation

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Knockdown of human MCM10 activates G2 checkpoint pathway

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Chk1 signaling pathways that mediated G2M checkpoint in relation to the cellular resistance to the novel topoisomerase I poison BNP1350

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Role of Chk1 and Chk2 in Ara‐C‐induced differentiation of human leukemia K562 cells

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Pirarubicin inhibits multidrug-resistant osteosarcoma cell proliferation through induction of G2/M phase cell cycle arrest

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Gossypin Induces G2/M Arrest in Human Malignant Glioma U251 Cells by the Activation of Chk1/Cdc25C Pathway

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RasGAP-derived peptide 38GAP potentiates the cytotoxicity of cisplatin through inhibitions of Akt, ERK and NF-κB in colon carcinoma HCT116 cells

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Hypoxia‐induced alterations of G2 checkpoint regulators

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Challenging the recalcitrant disease—developing molecularly driven treatments for small cell lung cancer

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Morphological Study of Metaphase‐Specific Apoptosis in MRL Mouse Testis

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Essential role of Chk1 in S phase progression through regulation of RNR2 expression

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The mammalian mid-pachytene checkpoint: meiotic arrest in spermatocytes with a mutation in Atm alone or in combination with a Trp53 (p53) or Cdkn1a (p21/cip1) mutation

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Human antibody derivatives against the fibroblast activation protein for tumor stroma targeting of carcinomas

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hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation

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Mechanism of DNA replication fork breakage and PARP1 hyperactivation during replication catastrophe

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Simaomicin α, a polycyclic xanthone, induces G1 arrest with suppression of retinoblastoma protein phosphorylation

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Checkpoint recovery in cells: how a molecular understanding can help in the fight against cancer

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Deciphering the DNA Damage Response

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Boromycin Abrogates Bleomycin-induced G2 Checkpoint

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Cooperative effect of p21Cip1/WAF−1 and 14-3-3σ on cell cycle arrest and apoptosis induction by p14ARF

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Potentiation of Bleomycin in Jurkat Cells by Fungal Pycnidione

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Differential deletions in 3p are associated with the development of head and neck squamous cell carcinoma in Indian patients

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UVA-activated 8-methoxypsoralen (PUVA) causes G2/M cell cycle arrest in Karpas 299 T-lymphoma cells

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Frequent allelic imbalance at the ATM locus in DNA multiploid colorectal carcinomas

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Inactivation of p42 Mitogen-activated Protein Kinase Is Required for Exit from M-phase after Cyclin Destruction

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The effects of ionizing radiation on DNA synthesis in eukaryotic cells

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Analysis of Fission Yeast Primase Defines the Checkpoint Responses to Aberrant S Phase Initiation

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A wide-ranging cellular response to UV damage of DNA

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Genome wide copy number analyses of superficial esophageal squamous cell carcinoma with and without metastasis

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MUS81 Inhibition Increases the Sensitivity to Therapy Effect in Epithelial Ovarian Cancer via Regulating CyclinB Pathway

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CHK1‐CDC25A‐CDK1 regulate cell cycle progression and protect genome integrity in early mouse embryos

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Desmoplastic small round cell tumor: from genomics to targets, potential paths to future therapeutics

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The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cells

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Pectenotoxin-2 induces G2/M phase cell cycle arrest in human breast cancer cells via ATM and Chk1/2-mediated phosphorylation of cdc25C

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Inhibition of Chk1 with the small molecule inhibitor V158411 induces DNA damage and cell death in an unperturbed S-phase

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Combined AURKA and H3K9 Methyltransferase Targeting Inhibits Cell Growth By Inducing Mitotic Catastrophe

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Cdc25B as a Steroid Receptor Coactivator

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DNA-damage response in the basidiomycete fungus Ustilago maydis relies in a sole Chk1-like kinase

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Regulation of Cdc25A Half-life in Interphase by Cyclin-dependent Kinase 2 Activity

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The role of Cdc25 phosphatases in cell cycle checkpoints

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Prospects for functional genomics in Schizosaccharomyces pombe

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Negative Regulation of Mitotic Promoting Factor by the Checkpoint Kinase Chk1 in Simian Virus 40 Lytic Infection

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Identification of Protein Kinase A Catalytic Subunit β as a Novel Binding Partner of p73 and Regulation of p73 Function

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HTLV-I Tax Related Dysfunction of Cell Cycle Regulators and Oncogenesis of Adult T Cell Leukemia

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An Integration of Old and New Perspectives of Mammalian Meiotic Sterility

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Interference of cell cycle progression by zidovudine and lamivudine in NIH 3T3 cells

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ATM in focus: A damage sensor and cancer target

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Effects of a checkpoint kinase inhibitor, AZD7762, on tumor suppression and bone remodeling

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From yeast to humans: Understanding the biology of DNA Damage Response (DDR) kinases

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A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress

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In vitro and In vivo Antiproliferative Effect of a Combination of Ultraviolet‐A and Alkoxy Furocoumarins Isolated from Umbelliferae Medicinal Plants, in Melanoma Cells

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Superparamagnetic Copper Ferrite Nanoparticles Catalyzed One Step Regioselective Synthesis of Dibenzodiazepinones via Ligand and Base Free Ullmann Type Coupling Reaction

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Phosphorylation of Cdc25C by pp90Rsk Contributes to a G2 Cell Cycle Arrest in Xenopus Cycling Egg Extracts

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Cell cycle dependent subcellular distribution of Cdc25B subtypes

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Pattern Formation in the Absence of Cell Proliferation: Tissue-Specific Regulation of Cell Cycle Progression by string (stg) during Drosophila Eye Development

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p34Cdc2 Kinase Activity Is Excluded from the Nucleus during the Radiation-induced G2 Arrest in HeLa Cells

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Radiosensitization of Tumor Cells by Modulation of ATM Kinase

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Combined Aurora Kinase A and CHK1 Inhibition Enhances Radiosensitivity of Triple-Negative Breast Cancer Through Induction of Apoptosis and Mitotic Catastrophe Associated With Excessive DNA Damage

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Sire modulates developmental kinetics and transcriptome of the bovine embryo

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DNA Damage in HeLa Cells Induced Arrest at a Discrete Point in G2Phase as Defined by CENP-F Localization

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Tubulozole-induced G2/M cell cycle arrest in human colon cancer cells through formation of microtubule polymerization mediated by ERK1/2 and Chk1 kinase activation

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Mammalian DNA Damage Response Pathway

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High levels of Cdc7 and Dbf4 proteins can arrest cell-cycle progression

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Pocket proteins and cell cycle regulation in inner ear development

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The DNA damage effector Chk1 kinase regulates Cdc14B nucleolar shuttling during cell cycle progression

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S-phase Inhibition of Cell Cycle Progression by a Novel Class of Pyridopyrimidine Tyrosine Kinase Inhibitors

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Nicotine Overrides DNA Damage-Induced G1/S Restriction in Lung Cells

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Tailoring an intravenously injectable oncolytic virus for augmenting radiotherapy

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ATRMec1 Phosphorylation-independent Activation of Chk1 in Vivo

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Human Glioma Cells Acquire Temozolomide Resistance After Repeated Drug Exposure Via DNA Mismatch Repair Dysfunction

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Quantitative Profiling of DNA Damage and Apoptotic Pathways in UV Damaged Cells Using PTMScan Direct

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CDC25B Acts as a Potential Target of PRKACA in Fertilized Mouse Eggs1

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PI3K-Related Kinases: Roles in Cell-Cycle Regulation and DNA Damage Responses

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p53‐mediated downregulation of Chk1 abrogates the DNA damage‐induced G2M checkpoint in K562 cells, resulting in increased apoptosis

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Cloning and Characterization of Liver-specific Isoform of Chk1 Gene from Rat

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DNA Damage and Replication Checkpoints in the Fission Yeast, Schizosaccharomyces pombe

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DNA Damage Induces p53-dependent Down-regulation of hCHK1

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A Human and Mouse Homolog of theSchizosaccharomyces pombe rad1+Cell Cycle Checkpoint Control Gene

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Palladium-catalysed regioselective N -arylation of anthranilamides: a tandem route for dibenzodiazepinone synthesis

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Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates

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Androgens Upregulate Cdc25C Protein by Inhibiting Its Proteasomal and Lysosomal Degradation Pathways

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3D-QSAR study of Chk1 kinase inhibitors based on docking

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Polyphyllin G exhibits antimicrobial activity and exerts anticancer effects on human oral cancer OECM-1 cells by triggering G2/M cell cycle arrest by inactivating cdc25C-cdc2

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Cell Cycle Effects in Radiation Oncology

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Estimation of the ligand-binding free energy of checkpoint kinase 1 via non-equilibrium MD simulations

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