The DOI matches its Crossref record.
Repair of Adult Rat Corticospinal Tract by Transplants of Olfactory Ensheathing Cells
Abstract
The upper cervical corticospinal tract was transected on one side in adult rats. A suspension of ensheathing cells cultured from adult rat olfactory bulb was injected into the lesion site. This induced unbranched, elongative growth of the cut corticospinal axons. The axons grew through the transplant and continued to regenerate into the denervated caudal host tract. Rats with complete transections and no transplanted cells did not use the forepaw on the lesioned side for directed reaching. Rats in which the transplanted cells had formed a continuous bridge across the lesion exhibited directed forepaw reaching on the lesioned side.*
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Citations
Cited by
Ramón-Cueto, A., Plant, G. W., Avila, J., & Bunge, M. B. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-10-03803.1998 · Cited by 710
Neuronal Intrinsic Mechanisms of Axon Regeneration
Liu, K., Tedeschi, A., Park, K. K., & He, Z. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113723 · Cited by 458
Vaynman, S., & Gomez-Pinilla, F. (2005) · Neurorehabilitation and Neural Repair · doi:10.1177/1545968305280753 · Cited by 420
Regulation of axonal regeneration after mammalian spinal cord injury
Zheng, B., & Tuszynski, M. H. (2023) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-022-00562-y · Cited by 328
Activating Transcription Factor 3 and the Nervous System
Hunt, D., Raivich, G., & Anderson, P. N. (2012) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2012.00007 · Cited by 162
“, 2002), and the implantation of olfactory glia (Li et al., 1997).”
Background
Metadata
- Authors
- Li, Y., Field, P. M., & Raisman, G.
- Venue
- Science
- Published
- 1997-09-26
- Volume
- 277
- Issue
- 5334
- Pages
- 2000-2002
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1990918954
- Cited by
- 869
- References
- 0
- FWCI
- 15.07
- Type
- journal article
- Language
- en
- Open access
- closed
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- Li, Y., Field, P. M., & Raisman, G. (1997). Repair of Adult Rat Corticospinal Tract by Transplants of Olfactory Ensheathing Cells. Science. https://doi.org/10.1126/science.277.5334.2000
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.