The DOI matches its Crossref record; 62 of the 62 references it cites were found in a registry or an index.
Nucleic Acid-Based Methods for the Detection of Cancer
Abstract
Continued elucidation of the genetic changes that drive cancer progression is yielding new and potentially powerful nucleic acid–based markers of neoplastic disease. Pilot studies indicate that these markers can be used to detect cancer cells in a variety of clinical settings with unprecedented precision. Nucleic acid–based markers may prove to be valuable tools for early detection of cancer in asymptomatic individuals, for confirmation or exclusion of a cancer diagnosis that is based on suspicious but nondiagnostic clinical material, for assessment of tumor burden in cancer patients, and for assessment of response to preventive approaches applied to healthy individuals who are at high risk of developing cancer. Examples of these markers, their potential applications, and the current practical limitations on their clinical use are reviewed here.
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Cites
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Cited by
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Metadata
- Authors
- Sidransky, D.
- Venue
- Science
- Published
- 1997-11-07
- Volume
- 278
- Issue
- 5340
- Pages
- 1054-1058
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2040540105
- Cited by
- 405
- References
- 62
- FWCI
- 8.82
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
