Nuclear Accumulation of NFAT4 Opposed by the JNK Signal Transduction Pathway

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Pro-inflammatory Cytokines and Environmental Stress Cause p38 Mitogen-activated Protein Kinase Activation by Dual Phosphorylation on Tyrosine and Threonine

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Transcription Factor ATF2 Regulation by the JNK Signal Transduction Pathway

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JNK is involved in signal integration during costimulation of T lymphocytes

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Nuclear Export of NF-ATc Enhanced by Glycogen Synthase Kinase-3

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T CELL ANTIGEN RECEPTOR SIGNAL TRANSDUCTION PATHWAYS

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Targeting CaN/NFAT in Alzheimer’s brain degeneration

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Therapeutic modulation of transcription factor activity

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Oxytocin-Stimulated NFAT Transcriptional Activation in Human Myometrial Cells

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MicroRNA-350 induces pathological heart hypertrophy by repressing both p38 and JNK pathways

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Regulation of c-Jun N-Terminal Kinase by the ORL1Receptor through Multiple G Proteins

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SIRT6 Suppresses NFATc4 Expression and Activation in Cardiomyocyte Hypertrophy

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Active Protein Kinase B Regulates TCR Responsiveness by Modulating Cytoplasmic-Nuclear Localization of NFAT and NF-κB Proteins

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NF-AT5: The NF-AT Family of Transcription Factors Expands in a New DirectionPreprint

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Activity-dependent NFATc3 nuclear accumulation in pericytes from cortical parenchymal microvessels

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Inhibition of NFAT Specifically in T Cells Prevents Allergic Pulmonary Inflammation

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Bystander effects induced by chemicals and ionizing radiation: evaluation of changes in gene expression of downstream MAPK targets

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Elevated Afterload, Neuroendocrine Stimulation, and Human Heart Failure Increase BNP Levels and Inhibit Preload-Dependent SERCA Upregulation

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Activation of the Calcineurin/NFAT Signalling Cascade Starts Early in Human Hypertrophic Myocardium

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Requirement of Two NFATc4 Transactivation Domains for CBP Potentiation

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Multiomic profiling of chronically activated CD4+ T cells identifies drivers of exhaustion and metabolic reprogramming

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JNK2 negatively regulates CD8+ T cell effector function and anti‐tumor immune response

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Do T cells care about the mitogen‐activated protein kinase signalling pathways?

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Kinetic mechanism and ATP‐binding site reactivity of p38γ MAP kinase

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Anti-cancer potential of persimmon (Diospyros kaki) leaves via the PDGFR-Rac-JNK pathway

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Dual regulation of LIM kinase 1 expression by cyclic AMP and calcium determines cofilin phosphorylation states during neuritogenesis in NG108-15 cells

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Genetic Screening for Regulators of Prz1, a Transcriptional Factor Acting Downstream of Calcineurin in Fission Yeast

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Signaling through Calcium, Calcineurin, and NF-AT in Lymphocyte Activation and DevelopmentPreprint

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Involvement of hydrogen peroxide in asbestos-induced NFAT activation

Li, J., Huang, C., Huang, B., Shi, X., Castranova, V., & Vallyathan, V. (2002) · Springer eBooks · doi:10.1007/978-1-4615-1087-1_18 · Cited by 23

Repression of FasL expression by retinoic acid involves a novel mechanism of inhibition of transactivation function of the nuclear factors of activated T‐cells

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Induction of ligand-specific PrPCsignaling in human neuronal cells

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The protective effect of Hederagenin on pulmonary fibrosis by regulating the Ras/JNK/NFAT4 axis in rats

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Localization of Calcineurin in the Mature and Developing Retina

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Nuclear Factor of Activated T3 Is a Negative Regulator of Ras-JNK1/2-AP-1–Induced Cell Transformation

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Calcineurin–nuclear factor of activated t cells regulation of Krox‐20 expression in Schwann cells requires elevation of intracellular cyclic AMP

Kipanyula, M. J., Woodhoo, A., Rahman, M., Payne, D., Jessen, K. R., & Mirsky, R. (2012) · Journal of Neuroscience Research · doi:10.1002/jnr.23131 · Cited by 23

Cot/Tpl2 and PKCζ cooperate in the regulation of the transcriptional activity of NFATc2 through the phosphorylation of its amino-terminal domain☆

Gómez‐Casero, E., San-Antonio, B., Iñiguez, M. A., & Fresno, M. (2007) · Cellular Signalling · doi:10.1016/j.cellsig.2007.02.010 · Cited by 22

Transient outward potassium channel: a heart failure mediator

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A Constitutively Nuclear Form of NFATx Shows Efficient Transactivation Activity and Induces Differentiation of CD4+CD8+ T Cells

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NFATc3 inhibits hepatocarcinogenesis and HBV replication via positively regulating RIG-I-mediated interferon transcription

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An updated review of the pharmacological effects and potential mechanisms of hederagenin and its derivatives

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GnRH Regulation of Jun and Atf3 Requires Calcium, Calcineurin, and NFAT

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The azetidine derivative, KHG26792 protects against ATP-induced activation of NFAT and MAPK pathways through P2X7 receptor in microglia

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Synthesis and SAR of 2-Phenoxypyridines as novel c-Jun N-terminal kinase inhibitors

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Ppt1‐deficiency dysregulates lysosomal Ca++ homeostasis contributing to pathogenesis in a mouse model of CLN1 disease

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Direct evidence for the critical role of NFAT3 in benzo[a]pyrene diol-epoxide-induced cell transformation through mediation of inflammatory cytokine TNF induction in mouse epidermal Cl41 cells

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Downregulation of NFAT3 Due to Lack of T-Box Transcription Factor TBX5 Is Crucial for Cytokine Expression in T Cells

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Global DNA methylation pattern involved in the modulation of differentiation potential of adipogenic and myogenic precursors in skeletal muscle of pigs

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UR-1505, a New Salicylate, Blocks T Cell Activation through Nuclear Factor of Activated T Cells

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Involvement of hydrogen peroxide in asbestos-induced NFAT activation

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Role of Transcription Factor NFAT in the Immune Response

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Gene-regulating protein kinases as important anti-inflammatory targets

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Cloning of karyopherin-α3 from Drosophila Through Its Interaction with the Nuclear Localization Sequence of Germ Cell-Less Protein

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Calcineurin Mediates the Gonadotropin-Releasing Hormone Effect on Expression of Both Subunits of the Follicle-Stimulating Hormone through Distinct Mechanisms

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JNK-dependent NFATc1 pathway positively regulates IL-13 gene expression induced by (–)-epigallocatechin-3-gallate in human basophilic KU812 cells

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NFAT transcription factor regulation by urocortin II in cardiac myocytes and heart failure

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Targeting protein kinases benefits cancer immunotherapy

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TEC and MAPK Kinase Signalling Pathways in T helper (TH) cell Development, TH2 Differentiation and Allergic Asthma

Kannan, Y. (2013) · Journal of Clinical & Cellular Immunology · doi:10.4172/2155-9899.s12-011 · Cited by 16

Nuclear factor of activated T-cells

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Grb3-3 Is Up-regulated in HIV-1-infected T-cells and Can Potentiate Cell Activation through NFATc

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Activation of the Jun N-Terminal Kinase Pathway by Friend Spleen Focus-Forming Virus and Its Role in the Growth and Survival of Friend Virus-Induced Erythroleukemia Cells

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Human TAFII130 Is a Coactivator for NFATp

Kim, L. J., Seto, A. G., Nguyen, T. N., & Goodrich, J. A. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.10.3503-3513.2001 · Cited by 15

Aquaporin-2 Promoter Is Synergistically Regulated by Nitric Oxide and Nuclear Factor of Activated T Cells

Borghese, M. F. A., Bettini, L. M., Nitta, C. H., de Frutos, S., Majowicz, M. P., & Bosc, L. V. G. (2011) · Nephron Extra · doi:10.1159/000333066 · Cited by 14

Role of the CCAAT/Enhancer-binding Protein NFATc2 Transcription Factor Cascade in the Induction of Secretory Phospholipase A2

Yang, T. T. C., Ung, P. M. U., Rincón, M., & Chow, C.-W. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m511214200 · Cited by 14

Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition

Yang, X. Y., Yang, T. T. C., Schubert, W., Factor, S. M., & Chow, C.-W. (2006) · Developmental Biology · doi:10.1016/j.ydbio.2006.11.036 · Cited by 14

dnRas stimulates autocrine–paracrine growth of regenerating muscle via calcineurin–NFAT–IL-4 pathway

Zádor, E. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.08.024 · Cited by 13

Integrin linked kinase regulates the transcription of AQP2 by NFATC3

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Negative feedback regulation of calcineurin-dependent Prz1 transcription factor by the CaMKK-CaMK1 axis in fission yeast

Barroso, E. C., Yance-Chávez, T., Kito, A., Sugiura, R., Gómez-Hierro, A., Giménez-Zaragoza, D., & Aligué, R. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku684 · Cited by 12

Multiple cytokines sharing the common receptor γ chain can induce CD154/CD40 ligand expression by human CD4+ T lymphocytes via a cyclosporin A‐resistant pathway

Fayen, J. D. (2001) · Immunology · doi:10.1046/j.1365-2567.2001.01296.x · Cited by 12

Pim-1 kinase enhances NFATc activity and neuroendocrine functions in PC12 cells

Glazova, M. V., Aho, T. L. T., Palmetshofer, A., Murashov, A. K., Scheinin, M., & Koskinen, P. J. (2005) · Molecular Brain Research · doi:10.1016/j.molbrainres.2005.04.003 · Cited by 11

Photosensitization and Redox Signaling

Matroule, J., & Piette, J. G. (2000) · Antioxidants and Redox Signaling · doi:10.1089/ars.2000.2.2-301 · Cited by 11

Substituting c-Jun N-terminal kinase-3 (JNK3) ATP-binding site amino acid residues with their p38 counterparts affects binding of JNK- and p38-selective inhibitors

Fricker, M., LoGrasso, P. V., Ellis, S., Wilkie, N. M., Hunt, P. A., & Pollack, S. J. (2005) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2005.04.013 · Cited by 11

Expression of pokeweed antiviral protein in mammalian cells activates c-Jun NH2-terminal kinase without causing apoptosis

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Role of FAP48 in HIV‐associated lipodystrophy

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Design and synthesis of 1-aryl-5-anilinoindazoles as c-Jun N-terminal kinase inhibitors

Jiang, R., Frąckowiak, B., Shin, Y., Song, X., Chen, W., Li, L., Cameron, M. D., Duckett, D. R., & Kamenecka, T. M. (2013) · Bioorganic & Medicinal Chemistry Letters · doi:10.1016/j.bmcl.2013.02.082 · Cited by 10

Expression of Twist2 is controlled by T-cell receptor signaling and determines the survival and death of thymocytes

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Impaired NFAT Transcriptional Activity in Antigen-Stimulated CD8 T Cells Linked to Defective Phosphorylation of NFAT Transactivation Domain

Leung–Theung–Long, S., Mondor, I., Guiraud, M., Esquerré-Lamare, C., Nageleekar, V., Paulet, P.-E., Rincón, M., & Guerder, S. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803539 · Cited by 10

Expression of Signaling Molecules in Progressive Multifocal Leukoencephalopathy

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Altered Redox Balance in the Development of Chronic Hypoxia-induced Pulmonary Hypertension

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Mécanismes moléculaires de l’activité des immunosuppresseurs actuels en transplantation : rôles du pharmacien

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RACK-1, a Receptor for Activated C Kinase, Interacts with the Transcription Factor NFAT and Represses Its Transactivation

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Role of C-Jun N-Terminal Kinases on a Stressed Epithelium: Time for Testing Isoform Specificity

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Synthesis and SAR of 2,4-diaminopyrimidines as potent c-jun N-terminal kinase inhibitors

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Characterization of DNA binding, transcriptional activation, and regulated nuclear association of recombinant human NFATp

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