The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking
Abstract
Essential to the dendritic cell system of antigen-presenting cells are the veiled dendritic cells that traverse afferent lymph to enter lymph nodes, where they initiate immune responses. The origin of veiled cells, which were discovered 20 years ago, is unclear. Monocytes cultured with endothelium differentiated into dendritic cells within 2 days, particularly after phagocytosing particles in subendothelial collagen. These nascent dendritic cells migrated across the endothelium in the ablumenal-to-lumenal direction, as would occur during entry into lymphatics. Monocytes that remained in the subendothelial matrix became macrophages. Therefore, monocytes have two potential fates associated with distinct patterns of migration.
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Cites
Rabinowitz, S. S., & Gordon, S. (1991) · The Journal of experimental medicine · doi:10.1084/jem.174.4.827 · Cited by 233
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Geissmann, F., Jung, S., & Littman, D. R. (2003) · Immunity · doi:10.1016/s1074-7613(03)00174-2 · Cited by 3,391
Antigen Presentation and T Cell Stimulation by Dendritic Cells
Guermonprez, P., Valladeau, J., Zitvogel, L., Théry, C., & Amigorena, S. (2002) · Annual Review of Immunology · doi:10.1146/annurev.immunol.20.100301.064828 · Cited by 1,926
Monocyte-Mediated Defense Against Microbial Pathogens
Serbina, N. V., Jia, T., Hohl, T. M., & Pamer, E. G. (2008) · Annual Review of Immunology · doi:10.1146/annurev.immunol.26.021607.090326 · Cited by 1,123
Immunity, atherosclerosis and cardiovascular disease
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Metadata
- Authors
- Randolph, G. J., Beaulieu, S., Lebecque, S., Steinman, R. M., & Muller, W. A.
- Venue
- Science
- Published
- 1998-10-16
- Volume
- 282
- Issue
- 5388
- Pages
- 480-483
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2015954946
- Cited by
- 809
- References
- 1
- FWCI
- 19.35
- Type
- journal article
- Language
- en
- Open access
- closed
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- Randolph, G. J., Beaulieu, S., Lebecque, S., Steinman, R. M., & Muller, W. A. (1998). Differentiation of Monocytes into Dendritic Cells in a Model of Transendothelial Trafficking. Science. https://doi.org/10.1126/science.282.5388.480
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
