The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Mitochondrial Evolution
Abstract
The serial endosymbiosis theory is a favored model for explaining the origin of mitochondria, a defining event in the evolution of eukaryotic cells. As usually described, this theory posits that mitochondria are the direct descendants of a bacterial endosymbiont that became established at an early stage in a nucleus-containing (but amitochondriate) host cell. Gene sequence data strongly support a monophyletic origin of the mitochondrion from a eubacterial ancestor shared with a subgroup of the α-Proteobacteria. However, recent studies of unicellular eukaryotes (protists), some of them little known, have provided insights that challenge the traditional serial endosymbiosis–based view of how the eukaryotic cell and its mitochondrion came to be. These data indicate that the mitochondrion arose in a common ancestor of all extant eukaryotes and raise the possibility that this organelle originated at essentially the same time as the nuclear component of the eukaryotic cell rather than in a separate, subsequent event.
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Cites
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The Hydrogen Hypothesis for the First Eukaryote
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An ancestral mitochondrial DNA resembling a eubacterial genome in miniature
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Self-citationThe Endosymbiont Hypothesis Revisited
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Self-citationHow good are deep phylogenetic trees?
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Linear mitochondrial genomes: 30 years down the line
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Cited by
Phylogenetic Classification and the Universal Tree
Doolittle, W. F. (1999) · Science · doi:10.1126/science.284.5423.2124 · Cited by 1,888
Redefining the invertebrate RNA virosphere
Shi, M., Lin, X.-D., Tian, J.-H., Chen, L.-J., Chen, X., Li, C.-X., Qin, X.-C., Li, J., Cao, J.-P., Eden, J.-S., et al. (2016) · Nature · doi:10.1038/nature20167 · Cited by 1,640
Extreme genome reduction in symbiotic bacteria
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Algae-bacteria interactions: Evolution, ecology and emerging applications
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Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network
Scarpulla, R. C. (2011) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2010.09.019 · Cited by 1,281
Metadata
- Authors
- Gray, M. W., Burger, G., & Lang, B. F.
- Venue
- Science
- Published
- 1999-03-05
- Volume
- 283
- Issue
- 5407
- Pages
- 1476-1481
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W4242123597
- Cited by
- 1,719
- References
- 7
- FWCI
- 20.44
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
