The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Regulation of the Mammalian Pineal by Non-rod, Non-cone, Ocular Photoreceptors
Abstract
In mammals, ocular photoreceptors mediate an acute inhibition of pineal melatonin by light. The effect of rod and cone loss on this response was assessed by combining the rd mutation with a transgenic ablation of cones ( cl ) to produce mice lacking both photoreceptor classes. Despite the loss of all known retinal photoreceptors, rd/rd cl mice showed normal suppression of pineal melatonin in response to monochromatic light of wavelength 509 nanometers. These data indicate that mammals have additional ocular photoreceptors that they use in the regulation of temporal physiology.
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Citations
Cites
Putative Human Blue-Light Photoreceptors hCRY1 and hCRY2 Are Flavoproteins
Hsu, D. S., Zhao, X., Zhao, S., Kazantsev, A., Wang, R.-P., Todo, T., Wei, Y.-F., & Sancar, A. (1996) · Biochemistry · doi:10.1021/bi962209o · Cited by 291
Cited by
Molecular analysis of mammalian circadian rhythms
Reppert, S. M., & Weaver, D. R. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.647 · Cited by 1,444
Thapan, K., Arendt, J., & Skene, D. J. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.t01-1-00261.x · Cited by 1,320
Measuring and using light in the melanopsin age
Lucas, R. J., Peirson, S. N., Berson, D. M., Brown, T. M., Cooper, H. M., Czeisler, C. A., Figueiro, M. G., Gamlin, P. D., Lockley, S. W., O’Hagan, J. B., et al. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2013.10.004 · Cited by 1,278
Self-citationA Novel Human Opsin in the Inner Retina
Provencio, I., Rodriguez, I. R., Jiang, G., Hayes, W. P., Moreira, E. F., & Rollag, M. D. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-02-00600.2000 · Cited by 1,290
Hattar, S., Lucas, R. J., Mrosovsky, N., Thompson, S., Douglas, R. H., Hankins, M. W., Lem, J., Biel, M., Hofmann, F., Foster, R. G., et al. (2003) · Nature · doi:10.1038/nature01761 · Cited by 1,245
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Metadata
- Authors
- Lucas, R. J., Freedman, M. S., Muñoz, M., Garcia-Fernández, J.-M., & Foster, R. G.
- Venue
- Science
- Published
- 1999-04-16
- Volume
- 284
- Issue
- 5413
- Pages
- 505-507
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1983875092
- Cited by
- 525
- References
- 1
- FWCI
- 9.88
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lucas, R. J., Freedman, M. S., Muñoz, M., Garcia-Fernández, J.-M., & Foster, R. G. (1999). Regulation of the Mammalian Pineal by Non-rod, Non-cone, Ocular Photoreceptors. Science. https://doi.org/10.1126/science.284.5413.505
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