The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Cryptochromes: Blue Light Receptors for Plants and Animals
Abstract
Cryptochromes are blue, ultraviolet-A photoreceptors. They were first characterized for Arabidopsis and are also found in ferns and algae; they appear to be ubiquitous in the plant kingdom. They are flavoproteins similar in sequence to photolyases, their presumptive evolutionary ancestors. Cryptochromes mediate a variety of light responses, including entrainment of circadian rhythms in Arabidopsis , Drosophila , and mammals. Sequence comparison indicates that the plant and animal cryptochrome families have distinct evolutionary histories, with the plant cryptochromes being of ancient evolutionary origin and the animal cryptochromes having evolved relatively recently. This process of repeated evolution may have coincided with the origin in animals of a modified circadian clock based on the PERIOD, TIMELESS, CLOCK, and CYCLE proteins.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Molecular Bases for Circadian Clocks
Dunlap, J. C. (1999) · Cell · doi:10.1016/s0092-8674(00)80566-8 · Cited by 2,900
The cryb mutation identifies cryptochrome as a circadian photoreceptor in Drosophila
Stanewsky, R., Kaneko, M., Emery, P., Beretta, B., Wager-Smith, K., Kay, S. A., Rosbash, M., & Hall, J. C. (1998) · Cell · doi:10.1016/s0092-8674(00)81638-4 · Cited by 968
Putative Human Blue-Light Photoreceptors hCRY1 and hCRY2 Are Flavoproteins
Hsu, D. S., Zhao, X., Zhao, S., Kazantsev, A., Wang, R.-P., Todo, T., Wei, Y.-F., & Sancar, A. (1996) · Biochemistry · doi:10.1021/bi962209o · Cited by 291
Cited by
The PPARs: From Orphan Receptors to Drug Discovery
Willson, T. M., Brown, P. J., Sternbach, D. D., & Henke, B. R. (2000) · Journal of Medicinal Chemistry · doi:10.1021/jm990554g · Cited by 1,816
mCRY1 and mCRY2 are essential components of the negative limb of the circadian clock feedback loop
Kume, K., Zylka, M. J., Sriram, S., Shearman, L. P., Weaver, D. R., Jin, X., Maywood, E. S., Hastings, M. H., & Reppert, S. M. (1999) · Cell · doi:10.1016/s0092-8674(00)81014-4 · Cited by 1,617
Molecular analysis of mammalian circadian rhythms
Reppert, S. M., & Weaver, D. R. (2001) · Annual Review of Physiology · doi:10.1146/annurev.physiol.63.1.647 · Cited by 1,444
A Model for Photoreceptor-Based Magnetoreception in Birds
Ritz, T., Adem, S., & Schulten, K. (2000) · Biophysical Journal · doi:10.1016/s0006-3495(00)76629-x · Cited by 1,176
Franklin, K. A. (2008) · New Phytologist · doi:10.1111/j.1469-8137.2008.02507.x · Cited by 801
Metadata
- Authors
- Cashmore, A. R., Jarillo, J. A., Wu, Y.-J., & Liu, D.
- Venue
- Science
- Published
- 1999-04-30
- Volume
- 284
- Issue
- 5415
- Pages
- 760-765
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1989535139
- Cited by
- 1,022
- References
- 3
- FWCI
- 93.45
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Cryptochromes: Blue Light Receptors for Plants and Animals. https://app.cochat.ai/papers/10.1126/science.284.5415.760
- The paper
- Cashmore, A. R., Jarillo, J. A., Wu, Y.-J., & Liu, D. (1999). Cryptochromes: Blue Light Receptors for Plants and Animals. Science. https://doi.org/10.1126/science.284.5415.760
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
