The DOI matches its Crossref record; 30 of the 30 references it cites were found in a registry or an index.
Positioning of the Mitotic Spindle by a Cortical-Microtubule Capture Mechanism
Abstract
Correct positioning of the mitotic spindle is critical for cell division and development. Spindle positioning involves a search-and-capture mechanism whereby dynamic microtubules find and then interact with specific sites on the submembrane cortex. Genetic, biochemical, and imaging experiments suggest a mechanism for cortical-microtubule capture. Bim1p, located at microtubule distal ends, bound Kar9p, a protein associated with the daughter cell cortex. Bim1p is the yeast ortholog of human EB1, a binding partner for the adenomatous polyposis coli tumor suppressor. EB1 family proteins may have a general role in linking the microtubule cytoskeleton to cortical polarity determinants.
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Cites
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Bni1p, a Yeast Formin Linking Cdc42p and the Actin Cytoskeleton During Polarized Morphogenesis
Evangelista, M., Blundell, K., Longtine, M. S., Chow, C. J., Adames, N., Pringle, J. R., Peter, M., & Boone, C. (1997) · Science · doi:10.1126/science.276.5309.118 · Cited by 647
Tau protein binds to microtubules through a flexible array of distributed weak sites.
Butner, K. A., & Kirschner, M. W. (1991) · The Journal of cell biology · doi:10.1083/jcb.115.3.717 · Cited by 550
Gönczy, P., Pichler, S., Kirkham, M., & Hyman, A. A. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.1.135 · Cited by 447
APC binds to the novel protein EB1.
Su, L.-K., Burrell, M., HILL, D. E., Gyuris, J., Brent, R., Wiltshire, R. N., Trent, J. M., Vogelstein, B., & Kinzler, K. W. (1995) · PubMed · Cited by 444
Microtubules and signal transduction
Gundersen, G. G., & Cook, T. A. (1999) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)80010-6 · Cited by 407
Imamura, H. (1997) · The EMBO Journal · doi:10.1093/emboj/16.10.2745 · Cited by 310
Kar9p Is a Novel Cortical Protein Required for Cytoplasmic Microtubule Orientation in Yeast
Miller, R. K., & Rose, M. D. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.140.2.377 · Cited by 264
Hyman, A. A. (1989) · The Journal of cell biology · doi:10.1083/jcb.109.3.1185 · Cited by 247
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Cited by
Yeast formins regulate cell polarity by controlling the assembly of actin cables
Sagot, I., Klee, S. K., & Pellman, D. (2002) · Nature Cell Biology · doi:10.1038/ncb719 · Cited by 408
Self-citationDrosophila EB1 is important for proper assembly, dynamics, and positioning of the mitotic spindle
Rogers, S. L., Rogers, G. C., Sharp, D. J., & Vale, R. D. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200202032 · Cited by 408
Beyond polymer polarity: how the cytoskeleton builds a polarized cell
Li, R., & Gundersen, G. G. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2522 · Cited by 379
MECHANISMS OF POLARIZED GROWTH AND ORGANELLE SEGREGATION IN YEAST
Pruyne, D., Legesse-Miller, A., Gao, L., Dong, Y., & Bretscher, A. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.103108 · Cited by 366
The Bub2p Spindle Checkpoint Links Nuclear Migration with Mitotic Exit
Pereira, G., Höfken, T., Grindlay, J., Manson, C. L., & Schiebel, E. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00002-2 · Cited by 324
Metadata
- Authors
- Lee, L., Tirnauer, J. S., Li, J., Schuyler, S. C., Liu, J. Y., & Pellman, D.
- Venue
- Science
- Published
- 2000-03-24
- Volume
- 287
- Issue
- 5461
- Pages
- 2260-2262
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1966828910
- Cited by
- 269
- References
- 30
- FWCI
- 12.56
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lee, L., Tirnauer, J. S., Li, J., Schuyler, S. C., Liu, J. Y., & Pellman, D. (2000). Positioning of the Mitotic Spindle by a Cortical-Microtubule Capture Mechanism. Science. https://doi.org/10.1126/science.287.5461.2260
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
