The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
A Role for Flavin Monooxygenase-Like Enzymes in Auxin Biosynthesis
Abstract
Although auxin is known to regulate many processes in plant development and has been studied for over a century, the mechanisms whereby plants produce it have remained elusive. Here we report the characterization of a dominant Arabidopsis mutant, yucca , which contains elevated levels of free auxin. YUCCA encodes a flavin monooxygenase–like enzyme and belongs to a family that includes at least nine other homologous Arabidopsis genes, a subset of which appears to have redundant functions. Results from tryptophan analog feeding experiments and biochemical assays indicate that YUCCA catalyzes hydroxylation of the amino group of tryptamine, a rate-limiting step in tryptophan-dependent auxin biosynthesis.
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Romano, C. P., Hein, M. B., & Klee, H. J. (1991) · Genes & Development · doi:10.1101/gad.5.3.438 · Cited by 232
Cited by
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Spaepen, S., Vanderleyden, J., & Remans, R. (2007) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2007.00072.x · Cited by 1,954
Auxin-responsive gene expression: genes, promoters and regulatory factors
Hagen, G., & Guilfoyle, T. (2002) · Plant Molecular Biology · doi:10.1023/a:1015207114117 · Cited by 1,262
Auxin inhibits endocytosis and promotes its own efflux from cells
Paciorek, T., Zažímalová, E., Ruthardt, N., Petrášek, J., Stierhof, Y.-D., Kleine-Vehn, J., Morris, D. A., Emans, N., Jürgens, G., Geldner, N., et al. (2005) · Nature · doi:10.1038/nature03633 · Cited by 772
Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts
van Berkel, W. J. H., Kamerbeek, N. M., & Fraaije, M. W. (2006) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2006.03.044 · Cited by 671
Phillips, K. A., Skirpan, A. L., Liu, X., Christensen, A., Slewinski, T. L., Hudson, C., Barazesh, S., Cohen, J. D., Malcomber, S., & McSteen, P. (2011) · The Plant Cell · doi:10.1105/tpc.110.075267 · Cited by 286
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Metadata
- Authors
- Zhao, Y., Christensen, S. K., Fankhauser, C., Cashman, J. R., Cohen, J. D., Weigel, D., & Chory, J.
- Venue
- Science
- Published
- 2001-01-12
- Volume
- 291
- Issue
- 5502
- Pages
- 306-309
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2055323344
- Cited by
- 1,225
- References
- 1
- FWCI
- 36.64
- Type
- journal article
- Language
- en
- Open access
- closed
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