The DOI matches its Crossref record; 10 of the 10 references it cites were found in a registry or an index.
Direct Polyclonal Activation of Human B Lymphocytes by the Acquired Immune Deficiency Syndrome Virus
Abstract
When B lymphocytes from normal human peripheral blood were incubated for 1 hour with the retrovirus that causes the acquired immune deficiency syndrome (AIDS), the B cells showed marked proliferation and differentiation. Proliferative responses to the virus peaked on day 4 and appeared to be independent of accessory cells. This finding was repeated with three separate viral isolates, one of which was from a patient from Zaire. The magnitude of the observed responses was comparable to that seen with standard polyclonal B-cell activators. This phenomenon may be at least partially responsible for the polyclonal B-cell activation seen in patients with AIDS.
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Cites
Barré-Sinoussi, F., Chermann, J. C., Rey, F., Nugeyre, M. T., Chamaret, S., Gruest, J., Dauguet, C., Axler-Blin, C., Vézinet-Brun, F., Rouzioux, C., et al. (1983) · Science · doi:10.1126/science.6189183 · Cited by 7,038
Gallo, R. C., Salahuddin, S. Z., Popovic, M., Shearer, G. M., Kaplan, M., Haynes, B. F., Palker, T. J., Redfield, R., Oleske, J., Safai, B., et al. (1984) · Science · doi:10.1126/science.6200936 · Cited by 3,641
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus
Dalgleish, A. G., Beverley, P. C. L., Clapham, P. R., Crawford, D. H., Greaves, M. F., & Weiss, R. A. (1984) · Nature · doi:10.1038/312763a0 · Cited by 3,533
The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration
Mogensen, C. E. (1968) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365516809076979 · Cited by 2,654
Lane, H. C., Masur, H., Edgar, L. C., Whalen, G., Rook, A. H., & Fauci, A. S. (1983) · New England Journal of Medicine · doi:10.1056/nejm198308253090803 · Cited by 1,600
Self-citationInfection of monocyte/macrophages by human T lymphotropic virus type III.
Ho, D. D., Rota, T. R., & Hirsch, M. S. (1986) · Journal of Clinical Investigation · doi:10.1172/jci112491 · Cited by 672
Herpesvirus Infections in the Acquired Immune Deficiency Syndrome
Quinnan, G. V. (1984) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1984.03350010038020 · Cited by 398
Montagnier, L., Gruest, J., Chamaret, S., Dauguet, C., Axler-Blin, C., Guétard, D., Nugeyre, M.-T., Barré‐Sinoussi, F., Chermann, J., Brunet, J., et al. (1984) · Science · doi:10.1126/science.6328661 · Cited by 349
Folks, T., Benn, S., Rabson, A., Theodore, T., Hoggan, M. D., Martin, M., Lightfoote, M., & Sell, K. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.13.4539 · Cited by 318
Self-citationBird, A. G., & Britton, S. (1979) · Immunological Reviews · doi:10.1111/j.1600-065x.1979.tb00272.x · Cited by 180
Cited by
Neuroleukin: A Lymphokine Product of Lectin-Stimulated T Cells
Gurney, M. E., Apatoff, B. R., Spear, G. T., Baumel, M. J., Antel, J. P., Bania, M. B., & Reder, A. T. (1986) · Science · doi:10.1126/science.3020690 · Cited by 195
Metadata
- Authors
- Schnittman, S. M., Lane, H. C., Higgins, S. E., Folks, T., & Fauci, A. S.
- Venue
- Science
- Published
- 1986-09-05
- Volume
- 233
- Issue
- 4768
- Pages
- 1084-1086
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1985143680
- Cited by
- 364
- References
- 10
- FWCI
- 6.53
- Type
- journal article
- Language
- en
- Open access
- closed
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- Schnittman, S. M., Lane, H. C., Higgins, S. E., Folks, T., & Fauci, A. S. (1986). Direct Polyclonal Activation of Human B Lymphocytes by the Acquired Immune Deficiency Syndrome Virus. Science. https://doi.org/10.1126/science.3016902
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
