Source of New Hope Against Malaria is in Short Supply

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Synthetic biology and the development of tools for metabolic engineering

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Synthetic Biology for Synthetic Chemistry

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Artemisone—A Highly Active Antimalarial Drug of the Artemisinin Class

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Malaria Chemotherapeutics Part I: History of Antimalarial Drug Development, Currently Used Therapeutics, and Drugs in Clinical Development

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Effects of arbuscular mycorrhiza and phosphorus application on artemisinin concentration in Artemisia annua L.

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Induction of multiple pleiotropic drug resistance genes in yeast engineered to produce an increased level of anti-malarial drug precursor, artemisinic acid

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Insights into the Mechanism of Action of Ferroquine. Relationship between Physicochemical Properties and Antiplasmodial Activity

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Pathway engineering for functional isoprenoids

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Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products

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Compartmentalized Metabolic Engineering for Artemisinin Biosynthesis and Effective Malaria Treatment by Oral Delivery of Plant Cells

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Effectiveness of two arbuscular mycorrhizal fungi on concentrations of essential oil and artemisinin in three accessions of Artemisia annua L.

Chaudhary, V., Kapoor, R., & Bhatnagar, A. K. (2008) · Applied Soil Ecology · doi:10.1016/j.apsoil.2008.04.003 · Cited by 108 · see citing works

Water deficit effect on the accumulation of biomass and artemisinin in annual wormwood(Artemisia annua L., Asteraceae)

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A constructive debate

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Lessons from nosocomial viral haemorrhagic fever outbreaks

Fisher‐Hoch, S. P. (2005) · British Medical Bulletin · doi:10.1093/bmb/ldh054 · Cited by 89 · see citing works

Developing an industrial artemisinic acid fermentation process to support the cost‐effective production of antimalarial artemisinin‐based combination therapies

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Emerging Global Trends in Advanced Manufacturing

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Efficient synthesis of functional isoprenoids from acetoacetate through metabolic pathway-engineered Escherichia coli

Harada, H., Yu, F., Okamoto, S., Kuzuyama, T., Utsumi, R., & Misawa, N. (2008) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-008-1724-7 · Cited by 79 · see citing works

Microbial biosynthesis of medicinally important plant secondary metabolites

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Enhancing artemisinin content in and delivery from Artemisia annua: a review of alternative, classical, and transgenic approaches

Wani, K. I., Choudhary, S., Zehra, A., Naeem, M., Weathers, P., & Aftab, T. (2021) · Planta · doi:10.1007/s00425-021-03676-3 · Cited by 74 · see citing works

Salicylic acid and methyl jasmonate but not Rose Bengal enhance artemisinin production through invoking burst of endogenous singlet oxygen

Guo, X.-X., Yang, X., Yang, R., & Zeng, Q.-P. (2010) · Plant Science · doi:10.1016/j.plantsci.2010.01.014 · Cited by 66 · see citing works

Metabolic engineering strategies for sesquiterpene production in microorganism

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Novel approaches and achievements in biosynthesis of functional isoprenoids in Escherichia coli

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Synthetic chemistry fuels interdisciplinary approaches to the production of artemisinin

Corsello, M. A., & Garg, N. K. (2014) · Natural Product Reports · doi:10.1039/c4np00113c · Cited by 53 · see citing works

Opportunities for enzyme catalysis in natural product chemistry

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Synthetic Strategies for Peroxide Ring Construction in Artemisinin

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Synthesis of hybrid 4-anilinoquinoline triazines as potent antimalarial agents, their in silico modeling and bioevaluation as Plasmodium falciparumtransketolase and β-hematin inhibitors

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Techno-economic evaluation of artemisinin extraction from Artemisia annua L. using supercritical carbon dioxide

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The impact of synthetic biology on drug discovery

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Metabolic engineering of chloroplasts for artemisinic acid biosynthesis and impact on plant growth

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Assessment of Lethal, Sublethal, and Transgenerational Effects of Beauveria bassiana on the Demography of Aedes albopictus (Culicidae: Diptera)

Shoukat, R. F., Zafar, J., Shakeel, M., Zhang, Y., Freed, S., Xu, X., & Jin, F. (2020) · Insects · doi:10.3390/insects11030178 · Cited by 40 · see citing works

Synergistic re-channeling of mevalonate pathway for enhanced artemisinin production in transgenic Artemisia annua

Feng, L.-L., Yang, R.-Y., Yang, X.-Q., Zeng, X.-M., Lu, W.-J., & Zeng, Q.-P. (2009) · Plant Science · doi:10.1016/j.plantsci.2009.03.014 · Cited by 39 · see citing works

Supplying plant natural products by yeast cell factories

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Efeito alelopático de Artemisia annua L. na germinação e desenvolvimento inicial de plântulas de alface (Lactuca sativa L.) e leiteiro (Euphorbia heterophylla L.)

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Variation in the Volatile Constituents of Artemisia annua var. CIM-Arogya during Plant Ontogeny

Padalia, R. C., Verma, R. S., Chauhan, A., Chanotiya, C. S., & Yadav, A. K. (2011) · Natural Product Communications · doi:10.1177/1934578x1100600221 · Cited by 36 · see citing works

Nd and Pb isotope evolution of deep water masses in the eastern Indian Ocean during the past 33 Myr

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Perspectives on Using Physcomitrella Patens as an Alternative Production Platform for Thapsigargin and Other Terpenoid Drug Candidates

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Pathogenicity and Transgenerational Effects of Metarhizium anisopliae on the Demographic Parameters of Aedes albopictus (Culicidae: Diptera)

Shoukat, R. F., Hassan, B., Shakeel, M., Zafar, J., Li, S., Freed, S., Xu, X., & Jin, F. (2019) · Journal of Medical Entomology · doi:10.1093/jme/tjz236 · Cited by 34 · see citing works

Exogenous hydrogen sulphide alleviates copper stress impacts in Artemisia annua L.: Growth, antioxidant metabolism, glandular trichome development and artemisinin biosynthesis

Nomani, L., Zehra, A., Choudhary, S., Wani, K. I., Naeem, M., Siddiqui, M. H., Khan, M. M. A., & Aftab, T. (2021) · Plant Biology · doi:10.1111/plb.13242 · Cited by 33 · see citing works

Essential oils of petal, leaf and stem of the antimalarial plant Artemisia annua

Goel, D., Singh, V., Ali, M., Mallavarupu, G. R., & Kumar, S. (2007) · Journal of Natural Medicines · doi:10.1007/s11418-006-0112-9 · Cited by 32 · see citing works

Artemisone—A Highly Active Antimalarial Drug of the Artemisinin Class

Haynes, R. K., Fugmann, B., Stetter, J., Rieckmann, K. H., Heilmann, H., Chan, H., Cheung, M., Lam, W. W. ‐., Wong, H. N., Croft, S. L., et al. (2006) · Angewandte Chemie · doi:10.1002/ange.200503071 · Cited by 31 · see citing works

Engineered Production of Bioactive Natural Products from Medicinal Plants

Fidan, Ö., Zhan, J., & Ren, J. (2022) · World Journal of Traditional Chinese Medicine · doi:10.4103/wjtcm.wjtcm_66_21 · Cited by 25 · see citing works

Efficient functional analysis system for cyanobacterial or plant cytochromes P450 involved in sesquiterpene biosynthesis

Harada, H., Shindo, K., Iki, K., 寺岡亜佑子, Okamoto, S., Yu, F., Hattan, J., Utsumi, R., & Misawa, N. (2011) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-010-3062-9 · Cited by 23 · see citing works

The Synthetic Nature of Biology

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Enantiomeric Isopulegol as the Chiral Pool in the Total Synthesis of Bioactive Agents

Le, T. M., & Szakonyi, Z. (2021) · The Chemical Record · doi:10.1002/tcr.202100194 · Cited by 21 · see citing works

Building a golden triangle for the production and use of artemisinin derivatives against falciparum malaria in Africa

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Heme alkylation by artemisinin and trioxaquines

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Design and De Novo Synthesis of 6-Aza-artemisinins

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Total Synthesis as a Vehicle for Collaboration

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Kinetic analysis of cytochrome P450 reductase fromArtemisia annuareveals accelerated rates of NADPH-dependent flavin reduction

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Volatile Metabolite Compositions of the Essential Oil from Aerial Parts of Ornamental and Artemisinin Rich Cultivars of<i>Artemisia annua</i>

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Rapid and Systematic Exploration of Chemical Space Relevant to Artemisinins: Anti-malarial Activities of Skeletally Diversified Tetracyclic Peroxides and 6-Aza-artemisinins

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Enzymatic Total Synthesis of Gibberellin A4from Acetate

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Optimization of Ultrasound-Assisted Extraction of Artemisinin fromArtemisia annuaL. by Response Surface Methodology

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cDNA Cloning and Functional Analyses of Ashitaba (Angelica keiskei) Sesquiterpene Synthase Genes

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Bridging Omics Technologies with Synthetic Biology in Yeast Industrial Biotechnology

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Artemisia annua: A Miraculous Herb to Cure Malaria

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In vitro antibacterial and cytotoxic activity of zinc oxide, iron oxide and silver nanoparticles synthesised from Artemisia afra

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Foundation technologies in synthetic biology: tools for use in understanding plant immunity

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Refining Metabolic Mass Transfer for Efficient Biosynthesis of Plant Natural Products in Yeast

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Response of Sweet Wormwood (Artemisia annua L.) to Different Rates of Inorganic Nitrogen Fertilizer in Semi-Arid Zimbabwe

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Metabolic Engineering of Escherichia coli for the Production of a Precursor to Artemisinin, an Antimalarial Drug

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Biotechnological Strategies for Advanced Biofuel Production

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Investigating the heterologous expression of plant secondary metabolic enzymes to produce curcuminoids and curcuminoid derivatives

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Lead Generation for Infectious Diseases through Rapid Synthesis of Skeletally Diverse Small Molecules Inspired by Artemisinin

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Biosynthèse des composés odorants chez différents Pelargonium utilisés pour la production d'huile essentielle

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