The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Detection of Minimal Residual Cells Carrying the t(14;18) by DNA Sequence Amplification
Abstract
By means of the polymerase chain reaction (PCR) technique, DNA sequences were amplified that flank the crossover sites of a characteristic chromosomal translocation for follicular lymphomas, t(14;18)(q32;q21). This technique permitted the detection of cells carrying the t(14;18) hybrid DNA sequences at a dilution of 1:100,000. The remission marrow and blood samples of a patient with follicular lymphoma and the t(14;18) failed to show any abnormality by morphological examination and conventional Southern blot analysis. However, the t(14;18) hybrid DNA sequences were detected by the PCR technique. Thus, this technique is a highly sensitive tool to detect minimal residual cells carrying the t(14;18) and has the potential to identify a subpopulation of patients with subclinical disease.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Saiki, R. K., Scharf, S., Faloona, F., Mullis, K. B., Horn, G. T., Erlich, H. A., & Arnheim, N. (1985) · Science · doi:10.1126/science.2999980 · Cited by 8,956
Cited by
Primer-Directed Enzymatic Amplification of DNA with a Thermostable DNA Polymerase
Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., Mullis, K. B., & Erlich, H. A. (1988) · Science · doi:10.1126/science.2448875 · Cited by 17,719
Gribben, J. G., Freedman, A. S., Neuberg, D., Roy, D. C., Blake, K. W., Woo, S. D., Grossbard, M. L., Rabinowe, S. N., Coral, F., Freeman, G. J., et al. (1991) · New England Journal of Medicine · doi:10.1056/nejm199111283252201 · Cited by 668
BCL2 translocation frequency rises with age in humans
Liu, Y., Hernandez, A. M., Shibata, D., & Cortopassi, G. A. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.19.8910 · Cited by 358
Downing, Jr., Head, D., Curcio-Brint, A., Hulshof, M., Motroni, T., Raimondi, S., Carroll, A., Drabkin, H., Willman, C., & Theil, K. (1993) · Blood · doi:10.1182/blood.v81.11.2860.2860 · Cited by 173
Metadata
- Authors
- Lee, M.-S., Chang, K.-S., Cabanillas, F., Freireich, E. J., Trujillo, J. M., & Stass, S. A.
- Venue
- Science
- Published
- 1987-07-10
- Volume
- 237
- Issue
- 4811
- Pages
- 175-178
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W1968087380
- Cited by
- 410
- References
- 1
- FWCI
- 34.69
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Detection of Minimal Residual Cells Carrying the t(14;18) by DNA Sequence Amplification. https://app.cochat.ai/papers/10.1126/science.3110950
- The paper
- Lee, M.-S., Chang, K.-S., Cabanillas, F., Freireich, E. J., Trujillo, J. M., & Stass, S. A. (1987). Detection of Minimal Residual Cells Carrying the t(14;18) by DNA Sequence Amplification. Science. https://doi.org/10.1126/science.3110950
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
