The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.
EK2 Derivatives of Bacteriophage Lambda Useful in the Cloning of DNA from Higher Organisms: The λgt WES System
Abstract
A derivative of bacteriophage λ has been modified and tested together with an appropriate host system to meet the criteria of EK2 biologic containment for cloning DNA from higher organisms. In this report certain of the safety features are summarized and some of the tests carried out to confirm the containment properties of the vector are described. The cloning efficiency of this system, together with available gene purification and hybrid screening technology, indicate that it can be used to clone DNA fragments carrying specific, unique mammalian genes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Charon Phages: Safer Derivatives of Bacteriophage Lambda for DNA Cloning
Blattner, F. R., Williams, B. G., Blechl, A. E., Denniston-Thompson, K., Faber, H. E., Furlong, L.-A., Grunwald, D. J., Kiefer, D. O., Moore, D. D., Schumm, J. W., et al. (1977) · Science · doi:10.1126/science.847462 · Cited by 913
Replication of bacteriophage λ DNA dependent on the function of host and viral genes
Enquist, L. W., & Skalka, A. (1973) · Journal of Molecular Biology · doi:10.1016/0022-2836(73)90016-8 · Cited by 270
Self-citationViable Molecular Hybrids of Bacteriophage Lambda and Eukaryotic DNA
Thomas, M., Cameron, J. R., & Davis, R. W. (1974) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.71.11.4579 · Cited by 241
Fate of Bacteriophage Lambda in Non-immune Germ-free Mice
Geier, M. R., Trigg, M. E., & Merril, C. R. (1973) · Nature · doi:10.1038/246221a0 · Cited by 190
Cited by
A phylogenetic analysis of the mycoplasmas: basis for their classification
Weisburg, W. G., Tully, J. G., Rose, D. L., Petzel, J. P., Oyaizu, H., Yang, D., Mandelco, L., Sechrest, J., Lawrence, T. G., & Van Etten, J. (1989) · Journal of Bacteriology · doi:10.1128/jb.171.12.6455-6467.1989 · Cited by 747
Carter, D. B., Deibel, M. R., Dunn, C. J., Tomich, C.-S. C., Laborde, A. L., Slightom, J. L., Berger, A. E., Bienkowski, M. J., Sun, F. F., McEwan, R. N., et al. (1990) · Nature · doi:10.1038/344633a0 · Cited by 601
Gene Transfer and Molecular Cloning of the Human NGF Receptor
Chao, M. V., Bothwell, M. A., Ross, A. H., Koprowski, H., Lanahan, A. A., Buck, C. R., & Sehgal, A. (1986) · Science · doi:10.1126/science.3008331 · Cited by 449
Nakano, H., Yamamoto, F., Neville, C., Evans, D., Mizuno, T., & Perucho, M. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.1.71 · Cited by 133
Metadata
- Authors
- Leder, P., Tiemeier, D., & Enquist, L.
- Venue
- Science
- Published
- 1977-04-08
- Volume
- 196
- Issue
- 4286
- Pages
- 175-177
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2035520923
- Cited by
- 406
- References
- 4
- FWCI
- 29.47
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: EK2 Derivatives of Bacteriophage Lambda Useful in the Cloning of DNA from Higher Organisms: The λgt WES System. https://app.cochat.ai/papers/10.1126/science.322278
- The paper
- Leder, P., Tiemeier, D., & Enquist, L. (1977). EK2 Derivatives of Bacteriophage Lambda Useful in the Cloning of DNA from Higher Organisms: The λgt WES System. Science. https://doi.org/10.1126/science.322278
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.