The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.
The Approaching Era of the Tumor Suppressor Genes
Abstract
Genes that can inhibit the expression of the tumorigenic phenotype have been detected by the fusion of normal and malignant cells, the phenotypic reversion of in vitro transformants, the induction of terminal differentiation of malignant cell lineages, the loss of "recessive cancer genes," the discovery of regulatory sequences in the immediate vicinity of certain oncogenes, and the inhibition of tumor growth by normal cell products. Such tumor suppressor genes will probably turn out to be as, if not more, diversified as the oncogenes. Consideration of both kinds of genes may reveal common or interrelated functional properties.
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Citations
Cites
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Cited by
G 1 Events and Regulation of Cell Proliferation
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Metadata
- Authors
- Klein, G.
- Venue
- Science
- Published
- 1987-12-11
- Volume
- 238
- Issue
- 4833
- Pages
- 1539-1545
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2039050546
- Cited by
- 461
- References
- 85
- FWCI
- 36.58
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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